4.7 Review

The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms

Journal

BIOMOLECULES
Volume 11, Issue 10, Pages -

Publisher

MDPI
DOI: 10.3390/biom11101544

Keywords

therapy; early diagnosis; theranostics; targeted delivery; medicinal chemistry

Funding

  1. Ministry of Science and Higher Education of the Russian Federation [075-15-2020-800]

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This review presents the main patterns of synthesis for theranostics platforms and examines various chemical methods and modern solutions applied in the field of medicine, as well as analyzing modern trends and development areas.
This review presents the main patterns of synthesis for theranostics platforms. We examine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of nanoparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine.

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