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Application of Programmable Tetrahedral Framework Nucleic Acid-Based Nanomaterials in Neurological Disorders: Progress and Prospects

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Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fbioe.2021.782237

Keywords

tetrahedral framework nucleic acid; tFNA; neurological disorders; DNA nanomaterials; tetrahedral DNA nanomaterials

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Tetrahedral framework nucleic acid (tFNA), a special DNA nanodevice, shows promise for treating neurological disorders due to its high programmability, biocompatibility, tissue permeability, and capacity for cell proliferation and differentiation. This review evaluates recent studies on the use and progress of tFNA-based nanomaterials in neurological disorders.
Tetrahedral framework nucleic acid (tFNA), a special DNA nanodevice, is widely applied in diverse biomedical fields. Due to its high programmability, biocompatibility, tissue permeability as well as its capacity for cell proliferation and differentiation, tFNA presents a powerful tool that could overcome potential barriers in the treatment of neurological disorders. This review evaluates recent studies on the use and progress of tFNA-based nanomaterials in neurological disorders.

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