4.7 Review

Collagen and Discoidin Domain Receptor 1 Partnership: A Multifaceted Role in the Regulation of Breast Carcinoma Cell Phenotype

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Probing invadosomes: technologies for the analysis of invadosomes

Shan-Shan Lin et al.

Summary: Invadosomes are critical actin structures for cell migration, invasion, and extracellular matrix remodeling, with their dynamic, proteolytic, and protrusive nature attracting scientists to develop new technologies for analysis. Through exciting methodologies, researchers have well characterized the biochemical and biophysical properties of invadosomes, elegantly explaining their biological and pathological effects on human health and diseases. The opposite regulatory mechanisms between invadosomes and focal adhesions have been explored, with speculation on a potential rule for their switching mechanism.

FEBS JOURNAL (2022)

Review Oncology

The Yin and Yang of Discoidin Domain Receptors (DDRs): Implications in Tumor Growth and Metastasis Development

Sandra Majo et al.

Summary: This study explores the role of collagens in the tumor microenvironment, as well as the different functions of DDRs in various cancers. It also discusses the complexity of anti-DDR therapies in cancer treatment, as well as the key factors in tumor development and metastasis.

CANCERS (2021)

Article Cell Biology

Tyrosine kinase-independent actions of DDR2 in tumor cells and cancer-associated fibroblasts influence tumor invasion, migration and metastasis

Craig E. Barcus et al.

Summary: Both tumor cell-intrinsic signals and tumor cell-extrinsic signals from cells within the tumor microenvironment influence tumor cell dissemination and metastasis. DDR2 may play a crucial role in breast cancer metastasis and treatment failures with tyrosine kinase inhibitors may be due to its kinase-independent functions.

JOURNAL OF CELL SCIENCE (2021)

Review Cell Biology

Guidelines and definitions for research on epithelial-mesenchymal transition

Jing Yang et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)

Article Cell Biology

LRP-1 Promotes Colon Cancer Cell Proliferation in 3D Collagen Matrices by Mediating DDR1 Endocytosis

Cao Cuong Le et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Aging-associated modifications of collagen affect its degradation by matrix metalloproteinases

Preety Panwar et al.

MATRIX BIOLOGY (2018)

Editorial Material Cell Biology

Multitasking discoidin domain receptors are involved in several and specific hallmarks of cancer

Elodie Henriet et al.

CELL ADHESION & MIGRATION (2018)

Article Multidisciplinary Sciences

Inhibition of tumor-microenvironment interaction and tumor invasion by small-molecule allosteric inhibitor of DDR2 extracellular domain

Whitney R. Grither et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Oncology

Collagen Alignment as a Predictor of Recurrence after Ductal Carcinoma In Situ

Matthew W. Conklin et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2018)

Review Pharmacology & Pharmacy

The extracellular matrix in breast cancer

Jacob Insua-Rodriguez et al.

ADVANCED DRUG DELIVERY REVIEWS (2016)

Review Biochemistry & Molecular Biology

EMT: 2016

M. Angela Nieto et al.

Article Geriatrics & Gerontology

Protein glycation - Between tissue aging and protection

Andreas Simm et al.

EXPERIMENTAL GERONTOLOGY (2015)

Article Biochemistry & Molecular Biology

Changes in Structural-Mechanical Properties and Degradability of Collagen during Aging-associated Modifications

Preety Panwar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Review Biochemistry & Molecular Biology

Breast Tumor Heterogeneity: Source of Fitness, Hurdle for Therapy

Shany Koren et al.

MOLECULAR CELL (2015)

Article Cell Biology

Hyaluronan in aged collagen matrix increases prostate epithelial cell proliferation

Mamatha Damodarasamy et al.

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2015)

Article Biophysics

3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence

Kristin M. Riching et al.

BIOPHYSICAL JOURNAL (2014)

Article Cell Biology

Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway

Amelie Juin et al.

JOURNAL OF CELL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Shedding of Discoidin Domain Receptor 1 by Membrane-type Matrix Metalloproteinases

Hsueh-Liang Fu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

MT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis

E. Maquoi et al.

ONCOGENE (2012)

Article Pathology

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

Matthew W. Conklin et al.

AMERICAN JOURNAL OF PATHOLOGY (2011)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Article Biochemistry & Molecular Biology

Migration inhibition of mammary epithelial cells by Syk is blocked in the presence of DDR1 receptors

Brit Neuhaus et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2011)

Article Multidisciplinary Sciences

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

Joseph H. Taube et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

Kandice R. Levental et al.

Article Biochemistry & Molecular Biology

Age-associated changes of extracellular matrix collagen impair lung cancer cell migration

Babett Bartling et al.

FASEB JOURNAL (2009)

Article Medicine, General & Internal

Collagen density promotes mammary tumor initiation and progression

Paolo P. Provenzano et al.

BMC MEDICINE (2008)

Review Oncology

Fibroblasts in cancer

R Kalluri et al.

NATURE REVIEWS CANCER (2006)

Article Multidisciplinary Sciences

The microenvironment of the tumour-host interface

LA Liotta et al.

NATURE (2001)