4.7 Article

Differential localization and limited cytotoxic potential of duodenal CD8+Tcells

Related references

Note: Only part of the references are listed.
Article Cell Biology

Human intestinal tissue-resident memory T cells comprise transcriptionally and functionally distinct subsets

Michael E. B. FitzPatrick et al.

Summary: This study investigates the transcriptional, phenotypic, and functional heterogeneity of human intestinal CD4(+) and CD8(+) T-RM cells using donor-derived T-RM cells from intestinal transplant recipients. Single-cell transcriptional profiling identifies two transcriptional states of CD8(+) T-RM cells, delineated by ITGAE and ITGB2 expression. The results describe the differential expression of cytotoxicity- and residency-associated genes in these populations, highlighting the complexity of T-RM cell diversity in the human intestine.

CELL REPORTS (2021)

Article Medicine, Research & Experimental

SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues

Carly E. Starke et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Biochemistry & Molecular Biology

The Identity of Human Tissue-Emigrant CD8+ T Cells

Marcus Buggert et al.

Article Immunology

Tissue-Resident T Cells and Other Resident Leukocytes

David Masopust et al.

Annual Review of Immunology (2019)

Article Immunology

Resident memory CD8 T cells persist for years in human small intestine

Raquel Bartolome-Casado et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2019)

Review Immunology

Location, location, location: Tissue resident memory T cells in mice and humans

Peter A. Szabo et al.

SCIENCE IMMUNOLOGY (2019)

Article Medicine, Research & Experimental

HIV-Specific T Cell Responses Are Highly Stable on Antiretroviral Therapy

Yinyan Xu et al.

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2019)

Article Biochemistry & Molecular Biology

Defining total-body AIDS-virus burden with implications for curative strategies

Jacob D. Estes et al.

NATURE MEDICINE (2017)

Article Immunology

Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies

Amanda M. Crooks et al.

JOURNAL OF INFECTIOUS DISEASES (2015)

Article Biochemistry & Molecular Biology

Spatial Map of Human T Cell Compartmentalization and Maintenance over Decades of Life

Joseph J. C. Thome et al.

Review Immunology

CD8+T-cell effector function and transcriptional regulation during HIV pathogenesis

Korey R. Demers et al.

IMMUNOLOGICAL REVIEWS (2013)

Article Medicine, General & Internal

Antiretroviral therapy and management of HIV infection

Paul A. Volberding et al.

LANCET (2010)

Article Immunology

Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy

Tae-Wook Chun et al.

JOURNAL OF INFECTIOUS DISEASES (2008)

Article Multidisciplinary Sciences

Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin

Andrew M. Intlekofer et al.

SCIENCE (2008)

Article Immunology

CTL fail to accumulate at sites of HIV-1 replication in lymphoid tissue

Elizabeth Connick et al.

JOURNAL OF IMMUNOLOGY (2007)

Article Immunology

Lack of decay of HIV-1 in gut-associated lymphoid tissue reservoirs in maximally suppressed individuals

Michael A. Poles et al.

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2006)

Article Biochemical Research Methods

Optimization of methods to assess human mucosal T-cell responses to HIV infection

BL Shacklett et al.

JOURNAL OF IMMUNOLOGICAL METHODS (2003)

Article Biochemistry & Molecular Biology

Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells

JD Siliciano et al.

NATURE MEDICINE (2003)