Journal
JOURNAL OF STOMATOLOGY ORAL AND MAXILLOFACIAL SURGERY
Volume 123, Issue 5, Pages E454-E457Publisher
ELSEVIER
DOI: 10.1016/j.jormas.2021.12.004
Keywords
Computerized surgical planning; Radiation; Fibula flap; Osteoradionecrosis
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Computerized surgical planning (CSP) is crucial in osseous reconstruction of head and neck cancer defects, but the impact of CSP-designed titanium plating systems on radiation therapy remains unclear, and there may be an underreported risk of osteoradionecrosis (ORN) and local recurrence.
Background: Computerized surgical planning (CSP) in osseous reconstruction of head and neck cancer defects has become a mainstay of treatment. However, the consequences of CSP-designed titanium plating systems on planning adjuvant radiation remains unclear. Methods: Two patients underwent head and neck cancer resection and maxillomandibular free fibula flap reconstruction with CSP-designed plates and immediate placement of osseointegrated dental implants. Surgical treatment was followed by adjuvant intensity modulated radiation therapy (IMRT). Results: Both patients developed osteoradionecrosis (ORN), and one patient had local recurrence. The locations of disease occurred at the areas of highest titanium plate burden, possibly attributed to IMRT dosing inaccuracy caused by the CSP-designed plating system. Conclusion: Despite proven benefits of CSP-designed plates in osseous free flap reconstruction, there may be an underreported risk to adjuvant IMRT treatment planning leading to ORN and/or local recurrence. Future study should investigate alternative plating methods and materials to mitigate this debilitating outcome. (c) 2021 Elsevier Masson SAS. All rights reserved.
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