Endothelial progenitor cells and coronary artery disease: Current concepts and future research directions

Vascular injury is a frequent pathology in coronary artery disease. To repair the vasculature, scientists have found that endothelial progenitor cells (EPCs) have excellent properties associated with angiogenesis. Over time, research on EPCs has made encouraging progress regardless of pathology or clinical technology. This review focuses on the origins and cell markers of EPCs, and the connection between EPCs and coronary artery disease. In addition, we summarized various studies of EPC-capturing stents and EPC infusion therapy, and aim to learn from past technology to predict the future.

Automated summary

Vascular injury is a common issue in coronary artery disease, and scientists have discovered that endothelial progenitor cells (EPCs) play a crucial role in angiogenesis. Research on EPCs has shown promising progress regardless of pathology or clinical technology. This review focuses on the origins and cell markers of EPCs, the connection with coronary artery disease, and past studies on EPC-capturing stents and EPC infusion therapy to inform future developments.