Journal
WORLD JOURNAL OF MENS HEALTH
Volume 40, Issue 1, Pages 52-65Publisher
KOREAN SOC SEXUAL MEDICINE & ANDROLOGY
DOI: 10.5534/wjmh.210022
Keywords
Semen analysis; Standardization; Quality assurance; Quality control
Funding
- American Center for Reproductive Medicine
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Semen analysis is a crucial test for evaluating male fertility potential and guiding infertility treatment. Both manual and automated semen analysis are important, and quality control and assurance play a vital role in ensuring reproducible results. Regular evaluation of laboratory technicians' performance is necessary for accuracy and precision.
Semen analysis is a basic test for evaluating male fertility potential, as it plays an essential role in driving the future management and treatment of infertility in couples. Manual semen analysis includes the evaluation of both macroscopic and microscopic parameters, whereas automated semen analysis is conducted through a computer-aided sperm analysis system and can include additional parameters that are not evaluated by manual analysis. Both quality control (QC) and quality assurance (QA) are important to ensure reproducible results for semen analysis, and represent fundamental checks and balances of all stages (pre-analytical, analytical, and post-analytical) of semen analysis. To ensure accuracy and precision, the laboratory technicians' performance should be evaluated biannually. This narrative review aims to describe standardized laboratory procedures for an accurate assessment of semen parameters that incorporate both QC and QA practices.
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