Journal
WORLD JOURNAL OF MENS HEALTH
Volume 40, Issue 1, Pages 30-37Publisher
KOREAN SOC SEXUAL MEDICINE & ANDROLOGY
DOI: 10.5534/wjmh.210056
Keywords
DNA fragmentation; Male infertility; Oxidative stress; Practice guidelines as topic; Reproductive techniques; assisted
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This article evaluates and compares two clinical practice guidelines on sperm DNA fragmentation, finding similar recommendations and highlighting differences between them. The best practice recommendations from both guidelines are summarized and combined.
Sperm DNA fragmentation (SDF) is implicated in male infertility and adverse reproductive outcomes. With the publication of many studies regarding the etiologies and contributors to SDF, as well as the effects of SDF, guidelines are necessary to aid clinicians in the application of SDF for male fertility evaluation. Two recent clinical practice guidelines were published by Agarwal et al and Esteves et al. In this article, we have evaluated and compared both guidelines. We have found fairly similar recommendations between the two guidelines and have also highlighted the differences between them. Finally, we have summarized and combined the best practice recommendations from both guidelines.
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