4.4 Article

Encephalitis Caused by Jamestown Canyon Virus in a Liver Transplant Patient, North Carolina, USA, 2017

Journal

OPEN FORUM INFECTIOUS DISEASES
Volume 9, Issue 3, Pages -

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofac031

Keywords

arboviruses; encephalitis; immunocompromised host; emerging infectious diseases; vector-borne diseases

Funding

  1. National Heart, Lung, and Blood Institute within the National Institutes of Health (NIH) [T32HL007106]
  2. National Institute of Allergy and Infectious Diseases within the National Institutes of Health (NIH) [T32-AI007151]
  3. National Center for Advancing Translational Sciences within the National Institutes of Health (NIH) [TL1TR002491]

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This is the first documented case of JCV in North Carolina, where a liver transplant patient presented with acute symptoms including headache, aphasia, and confusion. Additionally, it is the first report of successful recovery from JCV encephalitis through treatment with intravenous immune globulin.
We describe the first documented case of Jamestown Canyon virus (JCV) in North Carolina, which occurred in a liver transplant patient who presented acutely with headache, aphasia, and confusion. This is also the first report of recovery from JCV encephalitis following treatment with intravenous immune globulin.

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