Journal
PHARMACEUTICS
Volume 13, Issue 12, Pages -Publisher
MDPI
DOI: 10.3390/pharmaceutics13122034
Keywords
silver nanoparticles; viral infection; antiviral activity; virus
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Nanotechnology has opened up new horizons in medicine, with silver nanoparticles showing potential to combat viruses. However, developing safe and effective antiviral drugs is challenging due to the complexity of virus replication and the need to avoid harming host cells.
Since the early 1990s, nanotechnology has led to new horizons in nanomedicine, which encompasses all spheres of science including chemistry, material science, biology, and biotechnology. Emerging viral infections are creating severe hazards to public health worldwide, recently, COVID-19 has caused mass human casualties with significant economic impacts. Interestingly, silver nanoparticles (AgNPs) exhibited the potential to destroy viruses, bacteria, and fungi using various methods. However, developing safe and effective antiviral drugs is challenging, as viruses use host cells for replication. Designing drugs that do not harm host cells while targeting viruses is complicated. In recent years, the impact of AgNPs on viruses has been evaluated. Here, we discuss the potential role of silver nanoparticles as antiviral agents. In this review, we focus on the properties of AgNPs such as their characterization methods, antiviral activity, mechanisms, applications, and toxicity.
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