4.6 Review

Potential Approaches Versus Approved or Developing Chronic Myeloid Leukemia Therapy

Related references

Note: Only part of the references are listed.
Editorial Material Hematology

Novel BCR-ABL1 tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia

Sara Malik et al.

EXPERT REVIEW OF HEMATOLOGY (2021)

Review Biochemistry & Molecular Biology

Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds

Assunta Saide et al.

Summary: Microalgae can produce compounds with allelopathic, antimicrobial, antioxidant, anti-inflammatory, anticancer, and other beneficial biological activities, which have potential for human health applications in pharmaceutical and other industrial fields. Further research is needed to fully exploit their potential.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Oncology

Third-line therapy for chronic myeloid leukemia: current status and future directions

Jorge Cortes et al.

Summary: CML is driven by the BCR-ABL1 fusion protein, making the ATP binding site of ABL1 an optimal target for TKIs. Despite improvements in prognosis, patients often fail treatment and require new therapeutic options.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)

Article Hematology

A phase 3, open-label, randomized study of asciminib, a STAMP inhibitor, vs bosutinib in CML after 2 or more prior TKIs

Delphine Rea et al.

Summary: Asciminib demonstrated superior efficacy compared to bosutinib in treating patients with CML-CP who are resistant or intolerant to >= 2 prior TKIs, with a favorable safety profile.

BLOOD (2021)

Article Chemistry, Medicinal

Bioactivity Screening of Antarctic Sponges Reveals Anticancer Activity and Potential Cell Death via Ferroptosis by Mycalols

Gennaro Riccio et al.

Summary: This study identified the active compound mycalols in sponge extracts that trigger ferroptosis in hepatocellular carcinoma cells. Further investigation revealed down-regulation of ULK1 and GALNT5, and up-regulation of MAPK8, associated with ferroptosis, at both gene and protein levels in the cells.

MARINE DRUGS (2021)

Review Oncology

Oncolytic Viruses and Hematological Malignancies: A New Class of Immunotherapy Drugs

Vanessa Innao et al.

Summary: The use of oncolytic viruses for tumor treatment shows potential by not only directly destroying tumor cells, but also by operating through multiple systems to change the tumor environment towards an anti-tumoral state. Current research focuses on evaluating the effectiveness of using oncolytic viruses in treating hematologic malignancies and finding the most efficient virus or treatment combinations.

CURRENT ONCOLOGY (2021)

Review Oncology

The role of bosutinib in the treatment of chronic myeloid leukemia

Carlo Gambacorti-Passerini et al.

FUTURE ONCOLOGY (2020)

Article Biochemistry & Molecular Biology

DNA Damage and DNA Damage Response in Chronic Myeloid Leukemia

Henning D. Popp et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Oncology

Novel therapeutic approaches in chronic myeloid leukemia

Nurgul Ozgur Yurttas et al.

LEUKEMIA RESEARCH (2020)

Article Hematology

Chronic myeloid leukemia: 2020 update on diagnosis, therapy and monitoring

Elias Jabbour et al.

AMERICAN JOURNAL OF HEMATOLOGY (2020)

Review Biotechnology & Applied Microbiology

Recent advances of oncolytic virus in cancer therapy

Moumita Mondal et al.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2020)

Article Multidisciplinary Sciences

First evidence of anticancer and antimicrobial activity in Mediterranean mesopelagic species

Chiara Lauritano et al.

SCIENTIFIC REPORTS (2020)

Review Chemistry, Medicinal

Pheophorbide a: State of the Art

Assunta Saide et al.

MARINE DRUGS (2020)

Review Hematology

Tyrosine kinase inhibitors and pregnancy in chronic myeloid leukemia: opinion, evidence, and recommendations

Elisabetta Abruzzese et al.

THERAPEUTIC ADVANCES IN HEMATOLOGY (2020)

Review Oncology

Past, Present and Future of Oncolytic Reovirus

Louise Mueller et al.

CANCERS (2020)

Article Multidisciplinary Sciences

Novel mutations in the kinase domain of BCR-ABL gene causing imatinib resistance in chronic myeloid leukemia patients

Chodimella Chandrasekhar et al.

SCIENTIFIC REPORTS (2019)

Review Oncology

Tyrosine Kinase Inhibitors Available for Chronic Myeloid Leukemia: Efficacy and Safety

Valentin Garcia-Gutierrez et al.

FRONTIERS IN ONCOLOGY (2019)

Review Oncology

BCR-ABL Independent Mechanisms of Resistance in Chronic Myeloid Leukemia

Federica Loscocco et al.

FRONTIERS IN ONCOLOGY (2019)

Review Oncology

Management of Chronic Myeloid Leukemia in Advanced Phase

Massimiliano Bonifacio et al.

FRONTIERS IN ONCOLOGY (2019)

Article Oncology

Caprine herpesvirus 1 (CpHV-1) as a potential candidate for oncolytic virotherapy

Serena Montagnaro et al.

CANCER BIOLOGY & THERAPY (2019)

Article Oncology

Nilotinib in the treatment of chronic myeloid leukemia

Tomasz Sacha et al.

FUTURE ONCOLOGY (2019)

Article Medicine, General & Internal

Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure

T. P. Hughes et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Biotechnology & Applied Microbiology

Ponatinib: a novel multi-tyrosine kinase inhibitor against human malignancies

Fiona H. Tan et al.

ONCOTARGETS AND THERAPY (2019)

Letter Pharmacology & Pharmacy

Low-Dose Ponatinib in Intolerant Chronic Myeloid Leukemia Patients: A Safe and Effective Option

Alessandra Iurlo et al.

CLINICAL DRUG INVESTIGATION (2018)

Article Biochemistry & Molecular Biology

Effects of antioxidants on apoptosis induced by dasatinib and nilotinib in K562 cells

Sara Damiano et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2018)

Review Chemistry, Medicinal

Marine Microalgae with Anti-Cancer Properties

Kevin A. Martinez Andrade et al.

MARINE DRUGS (2018)

Review Biochemistry & Molecular Biology

Non ABL-directed inhibitors as alternative treatment strategies for chronic myeloid leukemia

Michele Massimino et al.

MOLECULAR CANCER (2018)

Review Cell & Tissue Engineering

Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment

Elena Arrigoni et al.

STEM CELLS TRANSLATIONAL MEDICINE (2018)

Review Oncology

Ponatinib: A Review of Efficacy and Safety

Fulvio Massaro et al.

CURRENT CANCER DRUG TARGETS (2018)

Article Environmental Sciences

Marine microorganisms as a promising and sustainable source of bioactive molecules

G. Romano et al.

MARINE ENVIRONMENTAL RESEARCH (2017)

Article Multidisciplinary Sciences

The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1

Andrew A. Wylie et al.

NATURE (2017)

Article Medicine, Research & Experimental

Interleukin 3-receptor targeted exosomes inhibit in vitro and in vivo Chronic Myelogenous Leukemia cell growth

Daniele Bellavia et al.

THERANOSTICS (2017)

Review Hematology

Radotinib and its clinical potential in chronic-phase chronic myeloid leukemia patients: an update

Ahmet Emre Eskazan et al.

THERAPEUTIC ADVANCES IN HEMATOLOGY (2017)

Article Cell Biology

Comparison of Dasatinib, Nilotinib, and Imatinib in the Treatment of Chronic Myeloid Leukemia

Roberto Ciarcia et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2016)

Article Marine & Freshwater Biology

The marine biodiscovery pipeline and ocean medicines of tomorrow

Marcel Jaspars et al.

JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM (2016)

Article Cell Biology

Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells

Bing Z. Carter et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Virology

Recent advances in oncolytic adenovirus therapies for cancer

Amanda Rosewell Shaw et al.

CURRENT OPINION IN VIROLOGY (2016)

Review Hematology

Epidemiology of chronic myeloid leukaemia: an update

Martin Hoglund et al.

ANNALS OF HEMATOLOGY (2015)

Review Oncology

Reactive oxygen species in redox cancer therapy

Lingying Tong et al.

CANCER LETTERS (2015)

Article Virology

Oncolytic parvoviruses: from basic virology to clinical applications

Antonio Marchini et al.

VIROLOGY JOURNAL (2015)

Editorial Material Hematology

Targeting the JAK2-STAT5 pathway in CML

Peter Valent

BLOOD (2014)

Article Plant Sciences

Suvanine Sesterterpenes and Deacyl Irciniasulfonic Acids from a Tropical Coscinoderma sp Sponge

Chang-Kwon Kim et al.

JOURNAL OF NATURAL PRODUCTS (2014)

Article Chemistry, Medicinal

New Cyclic Cystine Bridged Peptides from the Sponge Suberites waedoensis

Jinhaeng Song et al.

MARINE DRUGS (2014)

Editorial Material Cell Biology

Adding a new facet to STAT5 in CML Multitasking for leukemic cells

Wolfgang Warsch et al.

CELL CYCLE (2013)

Review Cell Biology

Extracellular vesicles: Exosomes, microvesicles, and friends

Graca Raposo et al.

JOURNAL OF CELL BIOLOGY (2013)

Article Plant Sciences

Gombamide A, a Cyclic Thiopeptide from the Sponge Clathria gombawuiensis

Jung-Kyun Woo et al.

JOURNAL OF NATURAL PRODUCTS (2013)

Article Oncology

Signal Transduction in the Chronic Leukemias: Implications for Targeted Therapies

Wesam Ahmed et al.

CURRENT HEMATOLOGIC MALIGNANCY REPORTS (2013)

Article Cell Biology

Biology and significance of the JAK/STAT signalling pathways

Hiu Kiu et al.

GROWTH FACTORS (2012)

Review Cell Biology

Impact of BCR-ABL mutations on patients with chronic myeloid leukemia

Andreas Hochhaus et al.

CELL CYCLE (2011)

Article Biochemistry & Molecular Biology

Antiproliferative Effect of Aaptamine on Human Chronic Myeloid Leukemia K562 Cells

Meihua Jin et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2011)

Review Genetics & Heredity

Epigenomics of leukemia: from mechanisms to therapeutic applications

Cristina Florean et al.

EPIGENOMICS (2011)

Article Oncology

Effect of imatinib therapy with and without turmeric powder on nitric oxide levels in chronic myeloid leukemia

Veena S Ghalaut et al.

JOURNAL OF ONCOLOGY PHARMACY PRACTICE (2011)

Article Biotechnology & Applied Microbiology

Bovine herpesvirus type 1 as a novel oncolytic virus

R. Rodrigues et al.

CANCER GENE THERAPY (2010)

Article Cell Biology

Dysregulated Calcium Homeostasis and Oxidative Stress in Chronic Myeloid Leukemia (CML) Cells

Roberto Ciarcia et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2010)

Article Medicine, Research & Experimental

Chronic myeloid leukemia: mechanisms of blastic transformation

Danilo Perrotti et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Medicine, General & Internal

Dasatinib versus Imatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia

Hagop Kantarjian et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Medicine, General & Internal

Nilotinib versus Imatinib for Newly Diagnosed Chronic Myeloid Leukemia

Giuseppe Saglio et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Plant Sciences

Photosynthetic marine organisms as a source of anticancer compounds

F. Folmer et al.

PHYTOCHEMISTRY REVIEWS (2010)

Review Biotechnology & Applied Microbiology

Armed replicating adenoviruses for cancer virotherapy

J. J. Cody et al.

CANCER GENE THERAPY (2009)

Article Biochemistry & Molecular Biology

OXIDATIVE STRESS AND ANTIOXIDANT STATUS IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA

Rizwan Ahmad et al.

INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Resveratrol as an antioxidant and pro-oxidant agent: mechanisms and clinical implications

C. Alarcn de la Lastral et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2007)

Review Biotechnology & Applied Microbiology

Herpes simplex virus 1 (HSV-1) for cancer treatment

Y. Shen et al.

CANCER GENE THERAPY (2006)

Article Biochemistry & Molecular Biology

Effect of resveratrol on high glucose-induced stress in human leukemia K562 cells

WH Chan

JOURNAL OF CELLULAR BIOCHEMISTRY (2005)

Review Oncology

Development of farnesyl transferase inhibitors: A review

NMGM Appels et al.

ONCOLOGIST (2005)

Article Multidisciplinary Sciences

Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop

S Roumiantsev et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)