4.6 Review

Research Progress of Gliomas in Machine Learning

Journal

CELLS
Volume 10, Issue 11, Pages -

Publisher

MDPI
DOI: 10.3390/cells10113169

Keywords

gliomas; machine learning; prediction; radiomics; gene expression

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Funding

  1. Key Projects in the Science & Technology Pillar Program of Tianjin [20YFZCSN00530]
  2. Independent Innovation Foundation of Tianjin University [2020XYF-0110, 2020XY-0058]

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This article reviews the current status, future trends, and challenges of machine learning in glioma research, highlighting the importance in precision cancer care. It discusses the key machine learning tools and algorithms in the literature, as well as the limitations in glioma prediction and diagnostics.
In the field of gliomas research, the broad availability of genetic and image information originated by computer technologies and the booming of biomedical publications has led to the advent of the big-data era. Machine learning methods were applied as possible approaches to speed up the data mining processes. In this article, we reviewed the present situation and future orientations of machine learning application in gliomas within the context of workflows to integrate analysis for precision cancer care. Publicly available tools or algorithms for key machine learning technologies in the literature mining for glioma clinical research were reviewed and compared. Further, the existing solutions of machine learning methods and their limitations in glioma prediction and diagnostics, such as overfitting and class imbalanced, were critically analyzed.

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