Related references
Note: Only part of the references are listed.The Prognostic Impact of HER2 Genetic and Protein Expression in Pancreatic Carcinoma-HER2 Protein and Gene in Pancreatic Cancer
Song-Hee Han et al.
DIAGNOSTICS (2021)
The EGF domains of MUC4 oncomucin interact with ErbB2 and mediate with ErbB2 and mediate tumorigenic activity of cancer cells tumorigenic activity of cancer cells represent new potential therapeutic represent new potential therapeutic targets
Nicolas Stoup et al.
FASEB JOURNAL (2021)
HER2-targeted therapies - a role beyond breast cancer
Do-Youn Oh et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2020)
EGF-Containing Membrane-Bound Mucins: A Hidden ErbB2 Targeting Pathway?
Maxime Liberelle et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis (vol 9, 16678 , 2019)
Maxime Liberelle et al.
SCIENTIFIC REPORTS (2020)
Unraveling mucin domains in cancer and metastasis: when protectors become predators
Koelina Ganguly et al.
CANCER AND METASTASIS REVIEWS (2020)
Unsupervised Hierarchical Clustering of Pancreatic Adenocarcinoma Dataset from TCGA Defines a Mucin Expression Profile that Impacts Overall Survival
Nicolas Jonckheere et al.
CANCERS (2020)
Gemcitabine-induced epithelial-mesenchymal transition-like changes sustain chemoresistance of pancreatic cancer cells of mesenchymal-like phenotype
Mehdi El Amrani et al.
MOLECULAR CARCINOGENESIS (2019)
Advances in HER2-Targeted Therapy: Novel Agents and Opportunities Beyond Breast and Gastric Cancer
Funda Meric-Bernstam et al.
CLINICAL CANCER RESEARCH (2019)
Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas
Nicolas Jonckheere et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2018)
TGF-βRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727
Vincent Drubay et al.
CANCERS (2018)
MUC13 interaction with receptor tyrosine kinase HER2 drives pancreatic ductal adenocarcinoma progression
S. Khan et al.
ONCOGENE (2017)
Cell membrane-anchored MUC4 promotes tumorigenicity in epithelial carcinomas
Pengpeng Xia et al.
ONCOTARGET (2017)
MUC4 mucin- a therapeutic target for pancreatic ductal adenocarcinoma
Shailendra K. Gautam et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2017)
A Comprehensive Outline of Trastuzumab Resistance Biomarkers in HER2 Overexpressing Breast Cancer
Otilia Menyhart et al.
CURRENT CANCER DRUG TARGETS (2015)
Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the THERAPY phase 1-2 trial
Eric Assenat et al.
ONCOTARGET (2015)
Computational close up on protein-protein interactions: how to unravel the invisible using molecular dynamics simulations?
Christin Rakers et al.
WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE (2015)
HER2-family signalling mechanisms, clinical implications and targeting in breast cancer
N. Elster et al.
BREAST CANCER RESEARCH AND TREATMENT (2015)
MUC4-induced nuclear translocation of β-catenin: A novel mechanism for growth, metastasis and angiogenesis in pancreatic cancer
Xiaofei Zhi et al.
CANCER LETTERS (2014)
Resistance to human epidermal growth factor receptor type 2-targeted therapies
Jean-Christophe Thery et al.
EUROPEAN JOURNAL OF CANCER (2014)
Membrane-bound mucin modular domains: From structure to function
Nicolas Jonckheere et al.
BIOCHIMIE (2013)
Investigational therapies targeting the ErbB (EGFR, HER2, HER3, HER4) family in GI cancers
Monica Dandona Desai et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2013)
The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family
N. Skrypek et al.
ONCOGENE (2013)
Targeting protein-protein interactions as an anticancer strategy
Andrei A. Ivanov et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2013)
Mesothelin Binding to CA125/MUC16 Promotes Pancreatic Cancer Cell Motility and Invasion via MMP-7 Activation
Shih-Hsun Chen et al.
SCIENTIFIC REPORTS (2013)
Protein Purification-free Method of Binding Affinity Determination by Microscale Thermophoresis
Lyuba Khavrutskii et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2013)
Mucin-based Targeted Pancreatic Cancer Therapy
Maria P. Torres et al.
CURRENT PHARMACEUTICAL DESIGN (2012)
Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone φ, ψ and Side-Chain χ1 and χ2 Dihedral Angles
Robert B. Best et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2012)
The Mucin MUC4 and Its Membrane Partner ErbB2 Regulate Biological Properties of Human CAPAN-2 Pancreatic Cancer Cells via Different Signalling Pathways
Nicolas Jonckheere et al.
PLOS ONE (2012)
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
Fabian Sievers et al.
MOLECULAR SYSTEMS BIOLOGY (2011)
Activity of recombinant cysteine-rich domain proteins derived from the membrane-bound MUC17/Muc3 family mucins
Samuel B. Ho et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2010)
The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers
Nicolas Jonckheere et al.
BIOCHIMIE (2010)
Muc4/MUC4 functions and regulation in cancer
Kermit L. Carraway et al.
FUTURE ONCOLOGY (2009)
ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor
Diego Alvarado et al.
NATURE (2009)
Protein structure homology modeling using SWISS-MODEL workspace
Lorenza Bordoli et al.
NATURE PROTOCOLS (2009)
Mucins in cancer: function, prognosis and therapy
Donald W. Kufe
NATURE REVIEWS CANCER (2009)
Restricted mobility of conserved residues in protein-protein interfaces in molecular simulations
Osman N. Yogurtcu et al.
BIOPHYSICAL JOURNAL (2008)
P-LINCS: A parallel linear constraint solver for molecular simulation
Berk Hess
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2008)
Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1α
Guillaume Piessen et al.
BIOCHEMICAL JOURNAL (2007)
The mucin muc4 potentiates neuregulin signaling by increasing the cell-surface populations of ErbB2 and ErbB3
Melanie Funes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer
Rita Nahta et al.
NATURE CLINICAL PRACTICE ONCOLOGY (2006)
Computational analysis of molecular basis of 1:1 interactions of NRG-1β wild-type and variants with ErbB3 and ErbB4
C Luo et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2005)
Regulating the dynamics of EGF receptor signaling in space and time
BZ Shilo
DEVELOPMENT (2005)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Biologic and therapeutic role of HER2 in cancer
S Ménard et al.
ONCOGENE (2003)
Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
HS Cho et al.
NATURE (2003)
Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor α
TPJ Garrett et al.
CELL (2002)
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains
H Ogiso et al.
CELL (2002)