Journal
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
Volume 26, Issue 4, Pages 405-419Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/09603123.2015.1135311
Keywords
Hydroxynaphthalene; hydroxyphenanthrene; hydroxypyrene; hydroxyfluorene; gender
Ask authors/readers for more resources
The objective of this study was to evaluate the association between thyroid function and exposure to selected polycyclic aromatic hydrocarbons (PAH) among those aged 20years. Thyroid variables considered for evaluation were thyroid-stimulating hormone, free and total serum thyroxine (FT4, TT4), free and total triiodothyronine (FT3, TT3), and thyroglobulin. PAH metabolites in urine for which data were analyzed were 1-hydroxynaphthalene, 2-hydroxynaphthalene, 2-hydroxyfluorene, 3-hydroxyfluorene, 9-hydroxyfluorene, 1-hydroxyphenanthrene, 2-hydroxyphenanthrene, 3-hydroxyphenanthrene, and 1-hydroxypyrene. Using data from 2007 to 2008 National Health and Nutrition Examination Survey, regression models with logs of thyroid variables as dependent variables and PAH exposure, age, race/ethnicity, iodine sufficiency, smoking status, and others as independent variables were fitted. For females, increased levels of 2-hydroxynapthalene, 2-hydroxyphenanthrene, and 1-hydroxypyrene were associated with elevated levels of TT3. For males, increased levels of 1-hydroxyphenanthrene, 2-hydroxyphenanthrene, and 9-hydroxypyrene were associated with decreased levels of FT4.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available