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CANCER IMMUNOLOGY IMMUNOTHERAPY (2012)
Phase II trial of hu14.18-IL2 for patients with metastatic melanoma
Mark R. Albertini et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2012)
Enhancement of metastatic ability by ectopic expression of ST6GalNAcI on a gastric cancer cell line in a mouse model
Hidenori Ozaki et al.
CLINICAL & EXPERIMENTAL METASTASIS (2012)
Analysis of Tn antigenicity with a panel of new IgM and IgG1 monoclonal antibodies raised against leukemic cells
Ola Blixt et al.
GLYCOBIOLOGY (2012)
Control of mucin-type O-glycosylation: A classification of the polypeptide GalNAc-transferase gene family
Eric P. Bennett et al.
GLYCOBIOLOGY (2012)
Epigenetic Silencing of the Chaperone Cosmc in Human Leukocytes Expressing Tn Antigen
Rongjuan Mi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Murine Anti-GD2 Monoclonal Antibody 3F8 Combined With Granulocyte-Macrophage Colony-Stimulating Factor and 13-Cis-Retinoic Acid in High-Risk Patients With Stage 4 Neuroblastoma in First Remission
Nai-Kong V. Cheung et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo
Nai-Kong V. Cheung et al.
ONCOIMMUNOLOGY (2012)
Effect of vaccination with N-glycolyl GM3/VSSP vaccine by subcutaneous injection in patients with advanced cutaneous melanoma
Marta Osorio et al.
Cancer Management and Research (2012)
Sialyl-Tn in Cancer: (How) Did We Miss the Target?
Sylvain Julien et al.
BIOMOLECULES (2012)
Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma
Chrystal U. Louis et al.
BLOOD (2011)
Antibody-Dependent Cell Cytotoxicity Synapses Form in Mice during Tumor-Specific Antibody Immunotherapy
Pascale Hubert et al.
CANCER RESEARCH (2011)
Human Monoclonal Antibodies to Sialyl-Lewisa (CA19.9) with Potent CDC, ADCC, and Antitumor Activity
Ritsuko Sawada et al.
CLINICAL CANCER RESEARCH (2011)
Occurrence of the human tumor-specific antigen structure Galβ1-3GalNAcα- (Thomsen-Friedenreich) and related structures on gut bacteria: Prevalence, immunochemical analysis and structural confirmation
Gemma Henderson et al.
GLYCOBIOLOGY (2011)
A new murine IgG1 anti-Tn monoclonal antibody with in vivo anti-tumor activity
Charlotte Welinder et al.
GLYCOBIOLOGY (2011)
A cytotoxic humanized anti-ganglioside antibody produced in a murine cell line defective of N-glycolylated-glycoconjugates
Yuniel Fernandez-Marrero et al.
IMMUNOBIOLOGY (2011)
Cimetidine inhibits the adhesion of gastric cancer cells expressing high levels of sialyl Lewis x in human vascular endothelial cells by blocking E-selectin expression
Fu-Rong Liu et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2011)
A pilot study of vaccination with sialyl Lewisa (sLea)-keyhole limpet hemocyanin (KLH) conjugate plus the immunologic adjuvant QS-21 in metastatic breast cancer patients (pts).
A. Diab et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Phase III Multicenter Clinical Trial of the Sialyl-TN (STn)-Keyhole Limpet Hemocyanin (KLH) Vaccine for Metastatic Breast Cancer
David Miles et al.
ONCOLOGIST (2011)
Immunology and immunotherapy of neuroblastoma
Robert C. Seeger
SEMINARS IN CANCER BIOLOGY (2011)
NGcGM3 Ganglioside: A Privileged Target for Cancer Vaccines
Luis E. Fernandez et al.
CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2010)
Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility
Sen-itiroh Hakomori
FEBS LETTERS (2010)
Immunogenicity and safety of a NeuGcGM3 based cancer vaccine Results from a controlled study in metastatic breast cancer patients
Vladimir Mulens et al.
HUMAN VACCINES (2010)
Ganglioside GD3 Enhances Adhesion Signals and Augments Malignant Properties of Melanoma Cells by Recruiting Integrins to Glycolipid-enriched Microdomains
Yuki Ohkawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Regulation of O-glycosylation through Golgi-to-ER relocation of initiation enzymes
David J. Gill et al.
JOURNAL OF CELL BIOLOGY (2010)
Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma.
Alice L. Yu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Sialyl-Tn vaccine induces antibody-mediated tumour protection in a relevant murine model
S. Julien et al.
BRITISH JOURNAL OF CANCER (2009)
Synthesis of sialyl Lewisa (sLea, CA19-9) and construction of an immunogenic sLea vaccine
Govind Ragupathi et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2009)
De-N-acetyl GM3 Promotes Melanoma Cell Migration and Invasion through Urokinase Plasminogen Activator Receptor Signaling-Dependent MMP-2 Activation
Ji-Wei Liu et al.
CANCER RESEARCH (2009)
The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
Martin A. Cheever et al.
CLINICAL CANCER RESEARCH (2009)
A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interaction
Carla Danussi et al.
GLYCOBIOLOGY (2009)
Structure and function of glycosphingolipids and sphingolipids: Recollections and future trends
Sen-Itiroh Hakomori
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2008)
Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains
Adriane Regina Todeschini et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2008)
Mouse-human chimeric anti-Tn IgG1 induced anti-tumor activity against Jurkat cells in vitro and in vivo
Hiroshi Ando et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2008)
Targeted gene therapy of LS174T human colon carcinoma by anti-TAG-72 immunoliposomes
K. S. Kim et al.
CANCER GENE THERAPY (2008)
Human tumor antigens to and sialyl Tn arise from mutations in Cosmc
Tongzhong Ju et al.
CANCER RESEARCH (2008)
Symptom and quality of life results of an international randomised phase III study of adjuvant vaccination with Bec2/BCG in responding patients with limited disease small-cell lung cancer
Andrew Bottomley et al.
EUROPEAN JOURNAL OF CANCER (2008)
Polysialylated NCAM represses E-cadherin-mediated cell-cell adhesion in pancreatic tumor cells
Susanne C. Schreiber et al.
GASTROENTEROLOGY (2008)
Mucin-type O-glycosylation in Mesocestoides vogae (syn. corti)
Andrea Medeiros et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY (2008)
Retargeting of human T cells to tumor-associated MUC1: The evolution of a chimeric antigen receptor
Scott Wilkie et al.
JOURNAL OF IMMUNOLOGY (2008)
Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
Martin A. Pule et al.
NATURE MEDICINE (2008)
Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells
Yuchao Gu et al.
BREAST CANCER RESEARCH (2008)
A polyvalent vaccine for high-risk prostate patients: are more antigens better?
Susan F. Slovin et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2007)
Targeting lewis y (Ley) in small cell lung cancer with a humanized monoclonal antibody, hu3S193:: A pilot trial testing two dose levels
Lee M. Krug et al.
JOURNAL OF THORACIC ONCOLOGY (2007)
The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma
Eirikur Saeland et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2007)
Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer
Paul J. Sabbatini et al.
CLINICAL CANCER RESEARCH (2007)
JAA-F11: extending the life of mice with breast cancer
Kate Rittenhouse-Olson
EXPERT OPINION ON BIOLOGICAL THERAPY (2007)
Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans
Guangyu An et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
A phase I biodistribution and pharmacokinetic trial of humanized monoclonal antibody Hu3s193 in patients with advanced epithelial cancers that express the Lewis-Y antigen
Andrew M. Scott et al.
CLINICAL CANCER RESEARCH (2007)
Biological significance of cancer-associated sialyl-Tn antigen: Modulation of malignant phenotype in gastric carcinoma cells
Sandra Pinho et al.
CANCER LETTERS (2007)
Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat
Mads A. Tarp et al.
GLYCOBIOLOGY (2007)
Expression of cancer-associated simple mucin-type O-glycosylated antigens in parasites
Eduardo Osinaga
IUBMB LIFE (2007)
A phase I study of an anti-GD3 monoclonal antibody, KW-2871, in patients with metastatic melanoma
Andres Forero et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2006)
Inhibition of spontaneous breast cancer metastasis by anti-Thomsen-Friedenreich antigen monoclonal antibody JAA-F11
Jamie Heimburg et al.
NEOPLASIA (2006)
PankoMab:: a potent new generation anti-tumour MUC1 antibody
Antje Danielczyk et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2006)
A mutant chaperone converts a wild-type protein into a tumor-specific antigen
Andrea Schietinger et al.
SCIENCE (2006)
A randomized, multicenter study to determine the safety and efficacy of the immunoconjugate SGN-15 plus docetaxel for the treatment of non-small cell lung carcinoma
Helen J. Ross et al.
LUNG CANCER (2006)
Glycosylation in cellular mechanisms of health and disease
Kazuaki Ohtsubo et al.
CELL (2006)
Preparation and evaluation of unimolecular pentavalent and hexavalent antigenic constructs targeting prostate and breast cancer: A synthetic route to anticancer vaccine candidates
G Ragupathi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Clinical evidences of GM3 (NeuGc) ganglioside expression in human breast cancer using the 14F7 monoclonal antibody labelled with 99mTc
Juan P. Oliva et al.
BREAST CANCER RESEARCH AND TREATMENT (2006)
Cellular and humoral immune response to N-glycolyl-GM3 elicited by prolonged immunotherapy with an anti-idiotypic vaccine in high-risk and metastatic breast cancer patients
MD Guthmann et al.
JOURNAL OF IMMUNOTHERAPY (2006)
ST6GalNAc I expression in MDA-MB-231 breast cancer cells greatly modifies their O-glycosylation pattern and enhances their tumourigenicity
S Julien et al.
GLYCOBIOLOGY (2006)
Carbohydrate array analysis of anti-Tn antibodies and lectins reveals unexpected specificities: Implications for diagnostic and vaccine development
JC Manimala et al.
CHEMBIOCHEM (2005)
Intraperitoneal radioimmunotherapy with a humanized anti-TAG-72 (CC49) antibody with a deleted CH2 region
BE Rogers et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2005)
Phase III study of adjuvant vaccination with Bec2/bacille Calmette-Guerin in responding patients with limited-disease small-cell lung cancer (European Organisation for Research and Treatment of Cancer 08971-0897113; Silva Study)
G Giaccone et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
High-dose radioimmunotherapy combined with fixed, low-dose paclitaxel in metastatic prostate and breast cancer by using a MUC-1 monoclonal antibody, m170, linked to indium-111/yttrium-90 via a cathepsin cleavable linker with cyclosporine to prevent human anti-mouse antibody
CM Richman et al.
CLINICAL CANCER RESEARCH (2005)
Thomsen-Friedenreich (TF) antigen as a target for prostate cancer vaccine: clinical trial results with TF cluster (c)-KLH plus QS21 conjugate vaccine in patients with biochemically relapsed prostate cancer
SF Slovin et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2005)
The sweet and sour of cancer: Glycans as novel therapeutic targets
MM Fuster et al.
NATURE REVIEWS CANCER (2005)
Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity
G Ragupathi et al.
JOURNAL OF IMMUNOLOGY (2005)
Vaccination of patients with small-cell lung cancer with synthetic fucosyl GM-1 conjugated to keyhole limpet hemocyanin
LM Krug et al.
CLINICAL CANCER RESEARCH (2004)
The discovery, biology, and drug development of sialyl Lea and sialyl Lex
JL Magnani
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
Sialyl-Tn antigen expression and O-linked GalNAc-Thr synthesis by Trypanosoma cruzi
T Freire et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Immunotherapy of advanced breast cancer with a heterophilic ganglioside (NeuGcGM3) cancer vaccine
A Carr et al.
JOURNAL OF CLINICAL ONCOLOGY (2003)
Fully synthetic carbohydrate-based vaccines in biochemically relapsed prostate cancer: Clinical trial results with alpha-N-acetylgalactosamine-O-serine/threonine conjugate vaccine
SF Slovin et al.
JOURNAL OF CLINICAL ONCOLOGY (2003)
Mucin-type O-glycosylation in Fasciola hepatica: characterisation of carcinoma-associated Tn and sialyl-Tn antigens and evaluation of UDP-GalNAc : polypeptide N-acetylgalactosaminyltransferase activity
T Freire et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY (2003)
The epitope recognized by the unique anti-MUC1 monoclonal antibody MY.1E12 involves sialylα2-3galactosylβ1-3N-acetylgalactosaminide linked to a distinct threonine residue in the MUC1 tandem repeat
H Takeuchi et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2002)
On the power of chemical synthesis: Immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines
G Ragupathi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Effect of glycosylation on MUC1 humoral immune recognition: NMR studies of MUC1 glycopeptide-antibody interactions
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BIOCHEMISTRY (2002)
Gangliosides with O-acetylated sialic acids in tumors of neuroectodermal origin
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NEUROCHEMICAL RESEARCH (2002)
An anti-GD2 monoclonal antibody enhances apoptotic effects of anti-cancer drugs against small cell lung cancer cells via JNK (c-jun terminal kinase) activation
S Yoshida et al.
JAPANESE JOURNAL OF CANCER RESEARCH (2002)
Cimetidine increases survival of colorectal cancer patients with high levels of sialyl Lewis-X and sialyl Lewis-A epitope expression on tumour cells
S Matsumoto et al.
BRITISH JOURNAL OF CANCER (2002)
NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3
H Moller et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
Targeting of GD2-positive tumor cells by human T lymphocytes engineered to express chimeric T-cell receptor genes
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INTERNATIONAL JOURNAL OF CANCER (2001)
Specific targeting, biodistribution, and lack of immunogenicity of chimeric anti-GD3 monoclonal antibody KM871 in patients with metastatic melanoma: Results of a phase I trial
AM Scott et al.
JOURNAL OF CLINICAL ONCOLOGY (2001)
Intraperitoneal radioimmunochemotherapy of ovarian cancer: A phase I study
RF Meredith et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2001)
Immunization of metastatic breast cancer patients with a fully synthetic globe H conjugate: A phase I trial
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Anti-tumor immunity provided by a synthetic multiple antigenic glycopeptide displaying a tri-Tn glycotope
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JOURNAL OF IMMUNOLOGY (2001)
Functional assessment in vitro of human-complement-dependent antibody-induced cytotoxicity of neoplastic cells
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CANCER IMMUNOLOGY IMMUNOTHERAPY (2000)
Production and functional characterization of two mouse/human chimeric antibodies with specificity for the tumor-associated Tn-antigen
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HYBRIDOMA (2000)
A mouse IgG1 monoclonal antibody specific for N-glycolyl GM3 ganglioside recognized breast and melanoma tumors
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HYBRIDOMA (2000)
Analysis of the fine specificity of Tn-binding proteins using synthetic glycopeptide epitopes and a biosensor based on surface plasmon resonance spectroscopy
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FEBS LETTERS (2000)
Clinical and immune responses in advanced melanoma patients immunized with an anti-idiotype antibody mimicking disialoganglioside GD2
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JOURNAL OF CLINICAL ONCOLOGY (2000)
Biochemical and functional characterization of the Tn-specific lectin from Salvia sclarea seeds
A Medeiros et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
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