Related references
Note: Only part of the references are listed.MYC Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma
Ravikanth Maddipati et al.
CANCER DISCOVERY (2022)
Krasmutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer
Kanchan Singh et al.
LABORATORY INVESTIGATION (2021)
Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Hyuna Sung et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2021)
Targeting MYC: From understanding its biology to drug discovery
Julie Ross et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
The pancreatic cancer genome revisited
Akimasa Hayashi et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)
Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing
Amrendra Mishra et al.
CARCINOGENESIS (2020)
Kras and Lkb1 mutations synergistically induce intraductal papillary mucinous neoplasm derived from pancreatic duct cells
Louis Collet et al.
GUT (2020)
The 2019 WHO classification of tumours of the digestive system
Iris D. Nagtegaal et al.
HISTOPATHOLOGY (2020)
Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution
Michelle Chan-Seng-Yue et al.
NATURE GENETICS (2020)
GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer
Grainne M. O'Kane et al.
CLINICAL CANCER RESEARCH (2020)
The Evolutionary Origins of Recurrent Pancreatic Cancer
Hitomi Sakamoto et al.
CANCER DISCOVERY (2020)
NCCN: Continuing Education
Mary B. Daly et al.
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2020)
TGF-β Signaling
Kalliopi Tzavlaki et al.
BIOMOLECULES (2020)
Update on GNA Alterations in Cancer: Implications for Uveal Melanoma Treatment
Lionel Larribere et al.
CANCERS (2020)
The biological basis and function ofGNASmutation in pseudomyxoma peritonei: a review
Yu-Lin Lin et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2020)
Mammalian SWI/SNF Chromatin Remodeling Complexes: Emerging Mechanisms and Therapeutic Strategies
Richard C. Centore et al.
TRENDS IN GENETICS (2020)
Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma
Alex Y. L. Lee et al.
GUT (2019)
ARID1A, a SWI/SNF subunit, is critical to acinar cell homeostasis and regeneration and is a barrier to transformation and epithelial-mesenchymal transition in the pancreas
Wenjia Wang et al.
GUT (2019)
PIN1 Maintains Redox Balance via the c-Myc/NRF2 Axis to Counteract Kras-Induced Mitochondrial Respiratory Injury in Pancreatic Cancer Cells
Chen Liang et al.
CANCER RESEARCH (2019)
Loss of Pten and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice
Janel L. Kopp et al.
GASTROENTEROLOGY (2018)
ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice
Yoshito Kimura et al.
GASTROENTEROLOGY (2018)
Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism
Krushna C. Patra et al.
NATURE CELL BIOLOGY (2018)
Mutations in BRCA1, BRCA2, and PALB2, and a panel of 50 cancer-associated genes in pancreatic ductal adenocarcinoma
Shoko Takeuchi et al.
SCIENTIFIC REPORTS (2018)
Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma
Koji Shindo et al.
JOURNAL OF CLINICAL ONCOLOGY (2017)
Pancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma
Olca Basturk et al.
MODERN PATHOLOGY (2017)
Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele
Jinghai Wu et al.
PLOS ONE (2017)
Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers
Nirakar Rajbhandari et al.
CELL REPORTS (2017)
ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer
Yiannis Drosos et al.
SCIENTIFIC REPORTS (2017)
The acinar regulator Gata6 suppresses KrasG12V-driven pancreatic tumorigenesis in mice
Paola Martinelli et al.
GUT (2016)
GNASR201H and KrasG12D cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm
K. Taki et al.
ONCOGENE (2016)
Physiologic Expression of Sf3b1K700E Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation
Esther A. Obeng et al.
CANCER CELL (2016)
Germline mutations in Japanese familial pancreatic cancer patients
Erina Takai et al.
ONCOTARGET (2016)
A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics
Ozhan Ocal et al.
DISEASE MODELS & MECHANISMS (2015)
GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma
Marcus C. Tan et al.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS (2015)
Whole genomes redefine the mutational landscape of pancreatic cancer
Nicola Waddell et al.
NATURE (2015)
Molecular Biomarkers for Progression of Intraductal Papillary Mucinous Neoplasm of the Pancreas
Yuko Kuboki et al.
PANCREAS (2015)
Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets
Agnieszka K. Witkiewicz et al.
NATURE COMMUNICATIONS (2015)
Pancreatic Cancer Metastases Harbor Evidence of Polyclonality
Ravikanth Maddipati et al.
CANCER DISCOVERY (2015)
PIK3CA mutations can initiate pancreatic tumorigenesis and are targetable with PI3K inhibitors
S. N. Payne et al.
ONCOGENESIS (2015)
GNAS Spectrum of Disorders
Serap Turan et al.
CURRENT OSTEOPOROSIS REPORTS (2015)
Clinicopathological significance of somatic RNF43 mutation and aberrant expression of ring finger protein 43 in intraductal papillary mucinous neoplasms of the pancreas
Hitomi Sakamoto et al.
MODERN PATHOLOGY (2015)
Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
Lola Rahib et al.
CANCER RESEARCH (2014)
A modular and flexible ESC-based mouse model of pancreatic cancer
Michael Saborowski et al.
GENES & DEVELOPMENT (2014)
Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas
Eliana Amato et al.
JOURNAL OF PATHOLOGY (2014)
The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma
Guido von Figura et al.
NATURE CELL BIOLOGY (2014)
RNF43 is frequently mutated in colorectal and endometrial cancers
Marios Giannakis et al.
NATURE GENETICS (2014)
A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer
Nina Schoenhuber et al.
NATURE MEDICINE (2014)
PTEN function: the long and the short of it
Benjamin D. Hopkins et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Acinar cell carcinomas of the pancreas: a molecular analysis in a series of 57 cases
Frank Bergmann et al.
VIRCHOWS ARCHIV (2014)
London Pancreas Workshop 2014 Edited by Hemanth Kocher Volume 14, Issue 2, Supplement 1, Pages e1-e6 (March-April 2014) Abstracts
[Anonymous]
PANCREATOLOGY (2014)
Frequent GNAS mutations in low-grade appendiceal mucinous neoplasms
G. Nishikawa et al.
BRITISH JOURNAL OF CANCER (2013)
Dormant Cancer Cells Contribute to Residual Disease in a Model of Reversible Pancreatic Cancer
Wan-chi Lin et al.
CANCER RESEARCH (2013)
The discrete nature and distinguishing molecular features of pancreatic intraductal tubulopapillary neoplasms and intraductal papillary mucinous neoplasms of the gastric type, pyloric gland variant
Hiroshi Yamaguchi et al.
JOURNAL OF PATHOLOGY (2013)
The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer
Morgan O'Hayre et al.
NATURE REVIEWS CANCER (2013)
Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
Haoqiang Ying et al.
CELL (2012)
EMT and Dissemination Precede Pancreatic Tumor Formation
Andrew D. Rhim et al.
CELL (2012)
Somatic Mutations in the Chromatin Remodeling Gene ARID1A Occur in Several Tumor Types
Sian Jones et al.
HUMAN MUTATION (2012)
Loss of expression of the SWI/SNF chromatin remodeling subunit BRG1/SMARCA4 is frequently observed in intraductal papillary mucinous neoplasms of the pancreas
Marco Dal Molin et al.
HUMAN PATHOLOGY (2012)
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
Bon-Kyoung Koo et al.
NATURE (2012)
Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer
A. Hunter Shain et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma
Karen M. Mann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A Central Role for RAF→MEK→ERK Signaling in the Genesis of Pancreatic Ductal Adenocarcinoma
Eric A. Collisson et al.
CANCER DISCOVERY (2012)
Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas
Janel L. Kopp et al.
DEVELOPMENT (2011)
Molecular characteristics and biological behaviours of the oncocytic and pancreatobiliary subtypes of intraductal papillary mucinous neoplasms
Hong D. Xiao et al.
JOURNAL OF PATHOLOGY (2011)
GATA6 Activates Wnt Signaling in Pancreatic Cancer by Negatively Regulating the Wnt Antagonist Dickkopf-1
Yi Zhong et al.
PLOS ONE (2011)
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways
Jian Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development
Jian Wu et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas
Toru Furukawa et al.
SCIENTIFIC REPORTS (2011)
High Cancer Risk in Peutz-Jeghers Syndrome: A Systematic Review and Surveillance Recommendations
M. G. F. van Lier et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2010)
Hot-spot mutations in p110α of phosphatidylinositol 3-kinase (PI3K) Differential interactions with the regulatory subunit p85 and with RAS
Li Zhao et al.
CELL CYCLE (2010)
Intraductal Tubulopapillary Neoplasms of the Pancreas Distinct From Pancreatic Intraepithelial Neoplasia and Intraductal Papillary Mucinous Neoplasms
Hiroshi Yamaguchi et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2009)
A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95
Takeyuki Sugiura et al.
EXPERIMENTAL CELL RESEARCH (2008)
Role of the GATA family of transcription factors in endocrine development, function, and disease
Robert S. Viger et al.
MOLECULAR ENDOCRINOLOGY (2008)
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
Sian Jones et al.
SCIENCE (2008)
LKB1 and AMPK in cell polarity and division
Tyisha Williams et al.
TRENDS IN CELL BIOLOGY (2008)
Mucinous cystic neoplasms of the pancreas: pathology and molecular genetics
Noriyoshi Fukushima et al.
JOURNAL OF HEPATO-BILIARY-PANCREATIC SURGERY (2007)
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinorna by k-Ras Oncogenes in adult mice
Carmen Guerra et al.
CANCER CELL (2007)
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer
Nabeel Bardeesy et al.
GENES & DEVELOPMENT (2006)
TGFβ:: the molecular Jekyll and Hyde of cancer
Brian Bierie et al.
NATURE REVIEWS CANCER (2006)
Frequency and spectrum of cancers in the Peutz-Jeghers syndrome
Nicholas Hearle et al.
CLINICAL CANCER RESEARCH (2006)
Back to the roots: the remarkable RAF oncogene story
A. Zebisch et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2006)
Classification of types of intraductal papillary-mucinous neoplasm of the pancreas:: a consensus study
T Furukawa et al.
VIRCHOWS ARCHIV (2005)
TGF-β and epithelial-to-mesenchymal transitions
J Zavadil et al.
ONCOGENE (2005)
Trp53R172H and KraSG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
SR Hingorani et al.
CANCER CELL (2005)
High frequency of mutations of the PIK3CA gene in human cancers
Y Samuels et al.
SCIENCE (2004)
An illustrated consensus on the classification of pancreatic Intraepithelial neoplasia and intraductal papillary mucinous neoplasms
RH Hruban et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2004)
Two related ARID family proteins are alternative subunits of human SWI/SNF complexes
XM Wang et al.
BIOCHEMICAL JOURNAL (2004)
Mouse models of pancreatic cancer: The fur is finally flying!
SD Leach
CANCER CELL (2004)
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma
AJ Aguirre et al.
GENES & DEVELOPMENT (2003)
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
SR Hingorani et al.
CANCER CELL (2003)
Mutations of the BRAF gene in human cancer
H Davies et al.
NATURE (2002)
Aberrant methylation of preproenkephalin and p16 genes in pancreatic Intraepithelial neoplasia and pancreatic ductal adenocarcinoma
N Fukushima et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
c-MYC activation in primary and metastatic ductal adenocarcinoma of the pancreas: Incidence, mechanisms, and clinical significance
C Schleger et al.
MODERN PATHOLOGY (2002)
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
EL Jackson et al.
GENES & DEVELOPMENT (2001)
STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas
N Sato et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
NE Sharpless et al.
NATURE (2001)
Exclusion of SMAD4 mutation as an early genetic change in human pancreatic ductal tumorigenesis
H Inoue et al.
GENES CHROMOSOMES & CANCER (2001)
Pancreatic intraepithelial neoplasia -: A new nomenclature and classification system for pancreatic duct lesions
RH Hruban et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2001)
Dpc4 protein in mucinous cystic neoplasms of the pancreas - Frequent loss of expression in invasive carcinomas suggests a role in genetic progression
CA Iacobuzio-Donahue et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2000)