Journal
CANCERS
Volume 13, Issue 19, Pages -Publisher
MDPI
DOI: 10.3390/cancers13194802
Keywords
cancer; sinonasal/nasal cavity/paranasal/sinus; surgery; endoscopic; radiotherapy
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This review provides an overview of the available radiotherapy techniques for sinonasal malignant tumors, emphasizing on its role as an adjuvant treatment after surgical resection and discussing the potential limitations and opportunities brought by the recent developments in endonasal endoscopic surgery.
Radiotherapy plays an important role in the treatment of sinonasal cancer, mainly in the adjuvant setting after surgical resection. Many technological approaches have been described, including intensity-modulated radiotherapy, concomitant chemoradiotherapy, charged particle therapy or combined approaches. The choice is based on general criteria related to the oncological results and morbidity of each technique and their availability, as well as specific criteria related to the tumor (tumor extensions, pathology and quality of margins). The aims of this review are: (i) to provide an overview of the radiotherapy techniques available for the management of sinonasal malignant tumors and (ii) to describe the constraints and opportunities of radiotherapy owing to the recent developments of endonasal endoscopic surgery. The indication and morbidity of the different techniques will be discussed based on a critical literature review.
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