4.7 Review

Current and Emerging Medical Therapies in Pituitary Tumors

Journal

JOURNAL OF CLINICAL MEDICINE
Volume 11, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/jcm11040955

Keywords

pituitary tumors; acromegaly; cushing's disease; prolactinoma; dopamine agonist; somatostatin

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This article reviews the current medical therapies used in the field of pituitary tumors, discusses the advantages and limitations of each treatment method, and specifies their positioning in the treatment algorithm for each phenotype. Furthermore, it provides insight into the future of medical therapies for pituitary tumors based on recent studies.
Pituitary tumors (PT) represent in, the majority of cases, benign tumors for which surgical treatment still remains, except for prolactin-secreting PT, the first-line therapeutic option. Nonetheless, the role played by medical therapies for the management of such tumors, before or after surgery, has evolved considerably, due in part to the recent development of well-tolerated and highly efficient molecules. In this review, our aim was to present a state-of-the-art of the current medical therapies used in the field of PT and the benefits and caveats for each of them, and further specify their positioning in the therapeutic algorithm of each phenotype. Finally, we discuss the future of PT medical therapies, based on the most recent studies published in this field.

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