The Challenge of Estimating Treatment Effects in Cardiac Surgery

Article Health Care Sciences & Services

No inexplicable disagreements between real-world data-based nonrandomized controlled studies and randomized controlled trials were found

Tim Mathes et al.

Summary: The study compared treatment effect estimates between nonrandomized controlled studies based on real-world data and randomized controlled trials, finding that in most cases there was overlap, with disagreements mainly attributed to bias risk in NRCS-RWDs.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2021)

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Review Medicine, General & Internal

Characteristics of Randomized Clinical Trials in Surgery From 2008 to 2020 A Systematic Review

N. Bryce Robinson et al.

Summary: A systematic review of contemporary surgical trials found that the trials were small in size and mainly focused on minor clinical events. Trial registration was suboptimal with frequent discrepancies between published protocol and reporting bias. Few trials controlled for surgeon experience or assessed intervention quality.

JAMA NETWORK OPEN (2021)

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Review Cardiac & Cardiovascular Systems

Randomized Trials in Cardiac Surgery JACC Review Topic of the Week

Mario Gaudino et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

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Editorial Material Surgery

The Evidence on the Ten Most Common Surgical Interventions in the United States From 1970 to 2018

Matthew Henry et al.

ANNALS OF SURGERY (2019)

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Article Cardiac & Cardiovascular Systems

Meta-Analysis Comparing Mitral Valve Repair Versus Replacement for Degenerative Mitral Regurgitation Across All Ages

Joon Chul Jung et al.

AMERICAN JOURNAL OF CARDIOLOGY (2019)

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Article Cardiac & Cardiovascular Systems

Long-term and short-term outcomes of using bilateral internal mammary artery grafting versus left internal mammary artery grafting: a meta-analysis

Sana N. Buttar et al.

HEART (2017)

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Article Cardiac & Cardiovascular Systems

Searching for the second best graft for coronary artery bypass surgery: a network meta-analysis of randomized controlled trials

Umberto Benedetto et al.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2015)

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The Challenge of Estimating Treatment Effects in Cardiac Surgery

Related references

No inexplicable disagreements between real-world data-based nonrandomized controlled studies and randomized controlled trials were found

Characteristics of Randomized Clinical Trials in Surgery From 2008 to 2020 A Systematic Review

Randomized Trials in Cardiac Surgery JACC Review Topic of the Week

The Evidence on the Ten Most Common Surgical Interventions in the United States From 1970 to 2018

Meta-Analysis Comparing Mitral Valve Repair Versus Replacement for Degenerative Mitral Regurgitation Across All Ages

Long-term and short-term outcomes of using bilateral internal mammary artery grafting versus left internal mammary artery grafting: a meta-analysis

Searching for the second best graft for coronary artery bypass surgery: a network meta-analysis of randomized controlled trials

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