Journal
CHEMISTRYSELECT
Volume 7, Issue 2, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/slct.202103829
Keywords
Base catalysis; 4-Cyano-3-arylquinolines; Cyclization; Heterocycles; o-Alkenylaryl isocyanides
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Funding
- National Natural Science Foundation of China [21702087, 21801105]
- LiaoNing Revitalization Talents Program [XLYC1907010, XLYC1902085]
- Research Project Fund of Liaoning Provincial Department of Education [L2020033, LJKZ0375]
- talent Scientific Research Fund of Liaoning Petrochemical University [2016XJJ-078, 2016XJJ-079]
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A novel base-catalyzed intramolecular self-cyclization reaction has been developed for the synthesis of 4-cyano-3-arylquinolines. This method offers a general, efficient, and atom-economic approach with a wide range of substrates and excellent functional group compatibilities.
A novel base-catalyzed intramolecular self-cyclization reaction of o-alkenylaryl isocyanides has been successfully developed. This reaction provides a general, efficient and atom-economic method to access 4-cyano-3-arylquinolines with broad scope of substrates and excellent functional group compatibilities.
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