Synthesis of 1-(3-(1-substituted-1,2,3-triazol-4-yl)-1,2,4-triazol-5-yl)-tetrazoles by Sequential Assembly of Azole Fragments

Only few efficient methods for the preparation of polyazoles containing three or four nitrogen atoms in each azole cycle exist. We have developed a novel synthetic strategy that allows the sequential assembly of 1,2,3-triazole, 1,2,4-triazole, and tetrazole fragments into a new stable polyazole. Along the novel strategy, some known procedures have been optimized to achieve better conversion, selectivity, and, in general, overall efficiency.

Automated summary

This research introduces a novel synthetic strategy for the preparation of polyazoles containing three or four nitrogen atoms in each azole cycle. Known procedures have been optimized to enhance conversion, selectivity, and overall efficiency.