4.4 Review

A Prospective Diversity of Antibacterial Small Peptidomimetic and Quorum Sensing Mediated Drug: A Review

Related references

Note: Only part of the references are listed.
Review Chemistry, Medicinal

Therapeutic Strategies To Counteract Antibiotic Resistance in MRSA Biofilm-Associated Infections

Stella Cascioferro et al.

Summary: Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of persistent human infections, with the ability to colonize asymptomatically and cause moderate to severe infections. It is considered a superbug due to its high morbidity and mortality rates, as well as its resistance to most antibiotics on the market. Its formation of biofilms on various surfaces is believed to be the primary means of its antibiotic resistance and widespread presence. Development of new anti-virulence strategies is crucial in combating MRSA infections associated with biofilms.

CHEMMEDCHEM (2021)

Editorial Material Chemistry, Medicinal

Novel strategies in the war against antibiotic resistance

Stella Cascioferro et al.

FUTURE MEDICINAL CHEMISTRY (2021)

Article Chemistry, Medicinal

Synthesis and biological evaluation of indole-based peptidomimetics as antibacterial agents against Gram-positive bacteria

Yongzhi Chen et al.

Summary: The emergence of bacterial multidrug resistance and the lack of new antimicrobial agents have led to the urgent need for the discovery and development of novel antibacterials. Antimicrobial peptidomimetics have shown promise in overcoming antibiotic resistance and are effective in rapidly killing bacteria without inducing resistance. Specific compounds have demonstrated potent activity against Gram-positive bacteria, low toxicity to mammalian cells, good stability, and high efficacy in treating bacterial infections.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Peptidomimetic Polyurethanes Inhibit Bacterial Biofilm Formation and Disrupt Surface Established Biofilms

Apoorva Vishwakarma et al.

Summary: Over 80% of chronic bacterial infections in humans are linked to biofilms, which provide significant resistance to antibiotics and host immune responses. Water-soluble synthetic peptidomimetic polyurethanes have shown potential in disrupting established biofilms and inhibiting biofilm formation without toxicity to mammalian cells.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Biochemistry & Molecular Biology

Membrane activity of two short Trp-rich amphipathic peptides

Jose C. Bozelli et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2020)

Article Chemistry, Multidisciplinary

Cyclam-based antibacterial molecules eradicate Gram-negative superbugs with potent efficacy against human corneal infection

Mohini Mohan Konai et al.

CHEMICAL COMMUNICATIONS (2020)

Article Chemistry, Medicinal

Synthesis and antimicrobial activity of novel 1,2,3-triazole-conjugates of quinazolin-4-ones

Iwona E. Glowacka et al.

ARCHIV DER PHARMAZIE (2019)

Article Multidisciplinary Sciences

Cationic Amphipathic Triazines with Potent Anti-bacterial, Anti-inflammatory and Anti-atopic Dermatitis Properties

Pethaiah Gunasekaran et al.

SCIENTIFIC REPORTS (2019)

Article Chemistry, Organic

Synthesis of novel sulfide-based cyclic peptidomimetic analogues to solonamides

Jose Brango Vanegas et al.

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY (2019)

Article Chemistry, Medicinal

Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents

Joanna Fedorowicz et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)

Article Multidisciplinary Sciences

A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier

Elizabeth M. Hart et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Chemistry, Medicinal

Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance

Barbara Parrino et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)

Review Infectious Diseases

Short Cationic Peptidomimetic Antimicrobials

Rajesh Kuppusamy et al.

ANTIBIOTICS-BASEL (2019)

Article Chemistry, Multidisciplinary

Selectively targeting bacteria by tuning the molecular design of membrane-active peptidomimetic amphiphiles

Mohini M. Konai et al.

CHEMICAL COMMUNICATIONS (2018)

Article Chemistry, Medicinal

Synthesis and antibacterial evaluation of novel cationic chalcone derivatives possessing broad spectrum antibacterial activity

Wen-Chao Chu et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)

Review Biochemistry & Molecular Biology

Current understanding of the human microbiome

Jack A. Gilbert et al.

NATURE MEDICINE (2018)

Article Multidisciplinary Sciences

Linear peptidomimetics as potent antagonists of Staphylococcus aureus agr quorum sensing

Georgia Karathanasi et al.

SCIENTIFIC REPORTS (2018)

Review Engineering, Biomedical

From Antimicrobial Peptides to Antimicrobial Poly(alpha-amino acid)s

Wei Shen et al.

ADVANCED HEALTHCARE MATERIALS (2018)

Article Environmental Sciences

Study of the In Vitro Antagonistic Activity of Various Single-Strain and Multi-Strain Probiotics against Escherichia coli

Sabina Fijan et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2018)

Review Biotechnology & Applied Microbiology

Quorum sensing intervened bacterial signaling: Pursuit of its cognizance and repression

Kayeen Vadakkan et al.

JOURNAL OF GENETIC ENGINEERING AND BIOTECHNOLOGY (2018)

Review Biochemistry & Molecular Biology

Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs

Natalia Molchanova et al.

MOLECULES (2017)

Article Chemistry, Organic

Amphipathic guanidine-embedded glyoxamide-based peptidomimetics as novel antibacterial agents and biofilm disruptors

Shashidhar Nizalapur et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2017)

Article Multidisciplinary Sciences

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

Michiru Nishita et al.

SCIENTIFIC REPORTS (2017)

Article Biochemistry & Molecular Biology

Development of a novel series of non-natural triaryl agonists and antagonists of the Pseudomonas aeruginosa LasR quorum sensing receptor

Joseph N. Capilato et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2017)

Article Biochemistry & Molecular Biology

Long-Chain 4-Aminoquinolines as Quorum Sensing Inhibitors in Serratia marcescens and Pseudomonas aeruginosa

Ivana Aleksic et al.

ACS CHEMICAL BIOLOGY (2017)

Review Microbiology

Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria

Clayton W. Hall et al.

FEMS MICROBIOLOGY REVIEWS (2017)

Review Biochemistry & Molecular Biology

Phage therapy: an alternative or adjunct to antibiotics?

Shawna McCallin et al.

EMERGING TOPICS IN LIFE SCIENCES (2017)

Article Engineering, Biomedical

Design and surface immobilization of short anti-biofilm peptides

Biswajit Mishra et al.

ACTA BIOMATERIALIA (2017)

Article Biochemistry & Molecular Biology

Antimicrobial activity of GN peptides and their mode of action

Troels Godballe et al.

BIOPOLYMERS (2016)

Editorial Material Biochemistry & Molecular Biology

Antimicrobial peptides

Ling-juan Zhang et al.

CURRENT BIOLOGY (2016)

Article Biochemistry & Molecular Biology

b Synergistic Antipseudomonal Effects of Synthetic Peptide AMP38 and Carbapenems

Hector Rudilla et al.

MOLECULES (2016)

Article Chemistry, Organic

Design, synthesis and evaluation of N-aryl-glyoxamide derivatives as structurally novel bacterial quorum sensing inhibitors

Shashidhar Nizalapur et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2016)

Review Immunology

The immunology of host defence peptides: beyond antimicrobial activity

Robert E. W. Hancock et al.

NATURE REVIEWS IMMUNOLOGY (2016)

Article Chemistry, Medicinal

Helical Antimicrobial Sulfono-γ-AApeptides

Yaqiong Li et al.

JOURNAL OF MEDICINAL CHEMISTRY (2015)

Article Chemistry, Medicinal

Potent Irreversible Inhibitors of LasR Quorum Sensing in Pseudomonas aeruginosa

Kevin T. O'Brien et al.

ACS MEDICINAL CHEMISTRY LETTERS (2015)

Article Biochemistry & Molecular Biology

Transformation of Human Cathelicidin LL-37 into Selective, Stable, and Potent Antimicrobial Compounds

Guangshun Wang et al.

ACS CHEMICAL BIOLOGY (2014)

Article Microbiology

Comparative Mechanistic Studies of Brilacidin, Daptomycin, and the Antimicrobial Peptide LL16

Bruk Mensa et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)

Article Biochemistry & Molecular Biology

In Vitro Antibacterial Screening of Six Proline-Based Cyclic Dipeptides in Combination with β-Lactam Antibiotics Against Medically Important Bacteria

S. Nishanth Kumar et al.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2014)

Review Infectious Diseases

Peptidomimetics as a new generation of antimicrobial agents: current progress

Patricia Mendez-Samperio

INFECTION AND DRUG RESISTANCE (2014)

Article Multidisciplinary Sciences

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

Jon A. Hagar et al.

SCIENCE (2013)

Review Chemistry, Medicinal

Antioxidant and Antimicrobial Activities of Cinnamic Acid Derivatives

M. Sova

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2012)

Article Chemistry, Physical

The antimicrobial peptide aurein 1.2 disrupts model membranes via the carpet mechanism

David I. Fernandez et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2012)

Article Biochemistry & Molecular Biology

Inhibition of LuxS by S-ribosylhomocysteine analogues containing a [4-aza]ribose ring

Venkata L. A. Malladi et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Substituted lactam and cyclic azahemiacetals modulate Pseudomonas aeruginosa quorum sensing

Venkata L. A. Malladi et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2011)

Review Biochemistry & Molecular Biology

Beyond natural antimicrobial peptides: multimeric peptides and other peptidomimetic approaches

Andrea Giuliani et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2011)

Review Biotechnology & Applied Microbiology

The expanding scope of antimicrobial peptide structures and their modes of action

Leonard T. Nguyen et al.

TRENDS IN BIOTECHNOLOGY (2011)

Review Genetics & Heredity

Gut microbiome-host interactions in health and disease

James M. Kinross et al.

GENOME MEDICINE (2011)

Article Chemistry, Multidisciplinary

Binaphthyl-Based Dicationic Peptoids with Therapeutic Potential

John B. Bremner et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Article Chemistry, Medicinal

Synthesis of novel sulfanilamide-derived 1,2,3-triazoles and their evaluation for antibacterial and antifungal activities

Xian-Long Wang et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)

Article Chemistry, Multidisciplinary

Covalent Inhibition of Bacterial Quorum Sensing

Neri Amara et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Article Chemistry, Medicinal

Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators

Grant D. Geske et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)

Review Biochemistry & Molecular Biology

Peptidomimetics, a synthetic tool of drug discovery

Josef Vagner et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2008)

Article Dentistry, Oral Surgery & Medicine

Identification of microbial biofilms in osteonecrosis of the jaws secondary to bisphosphonate therapy

Parish P. Sedghizadeh et al.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY (2008)

Article Microbiology

Novel Pseudomonas aeruginosa quorum-sensing inhibitors identified in an ultra-high-throughput screen

Ute Muh et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)

Review Microbiology

Penicillin binding proteins: key players in bacterial cell cycle and drug resistance processes

Pauline Macheboeuf et al.

FEMS MICROBIOLOGY REVIEWS (2006)

Review Microbiology

Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria?

KA Brogden

NATURE REVIEWS MICROBIOLOGY (2005)

Article Biochemistry & Molecular Biology

A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones

MW Vetting et al.

CHEMISTRY & BIOLOGY (2004)

Review Biochemistry & Molecular Biology

Resistance to β-lactam antibiotics

K Poole

CELLULAR AND MOLECULAR LIFE SCIENCES (2004)

Article Biochemistry & Molecular Biology

Interaction of cationic antimicrobial peptides with model membranes

LJ Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biophysics

Barrel-stave model or toroidal model? A case study on melittin pores

L Yang et al.

BIOPHYSICAL JOURNAL (2001)