Case Report: Infusion-Related Reactions to Intravenous Infliximab and Subcutaneous Ustekinumab in Pediatric Crohn's Disease

Review Gastroenterology & Hepatology

Immediate Infusion Reaction to Intravenous Ustekinumab in Three Crohn's Disease Patients: A Case Report and Review of the Literature

Pepijn W. A. Thomas et al.

Summary: This article reports on three therapy-refractory Crohn's disease patients who experienced immediate infusion reactions to intravenous administration of ustekinumab, with subsequent reactions to subcutaneous injections in two of the patients. Clinical features and pathophysiology are discussed.

JOURNAL OF CROHNS & COLITIS (2021)

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Article Gastroenterology & Hepatology

Ustekinumab for children and adolescents with inflammatory bowel disease at a tertiary children's hospital in Japan

Ichiro Takeuchi et al.

Summary: This study evaluated the clinical efficacy and safety of ustekinumab in children and adolescents with inflammatory bowel disease, showing that it may be an effective and safe treatment option for pediatric and adolescent patients with Crohn's disease or Crohn's disease-like inflammatory bowel disease who do not respond well to or have adverse reactions to anti-tumor necrosis factor agents.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Article Nutrition & Dietetics