☆ 4.6 Review

COVID-19-Related Mortality Risk in People With Severe Mental Illness: A Systematic and Critical Review

FRONTIERS IN PSYCHIATRY (2022)

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Review Pharmacology & Pharmacy

Vitamin D in the time of the coronavirus (COVID-19) pandemic - a clinical review from a public health and public mental health perspective

Ursula Werneke et al.

Summary: This review highlights the potential association between vitamin D deficiency and serious mental disorders as well as COVID-19 infection. While there is some evidence suggesting a link between vitamin D deficiency and depression or schizophrenia, the results from intervention studies are conflicting. Vitamin D supplementation may have a mitigating effect on the clinical course of COVID-19 infection, but further research is needed to understand its full impact.

THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY (2021)

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Review Psychiatry

Mental disorders and risk of COVID-19-related mortality, hospitalisation, and intensive care unit admission: a systematic review and meta-analysis

Benedetta Vai et al.

Summary: This systematic review and meta-analysis found that pre-existing mental disorders, specifically psychotic and mood disorders, and exposure to antipsychotics and anxiolytics were associated with an increased risk of COVID-19 mortality. The study highlighted the need for targeted approaches to manage and prevent COVID-19 in at-risk patient groups identified in this study. Further research is needed to determine the underlying mechanisms of these associations.

LANCET PSYCHIATRY (2021)

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Article Psychiatry

Mental health services during the first wave of the COVID-19 pandemic in Europe: Results from the EPA Ambassadors Survey and implications for clinical practice

Martina Rojnic Kuzman et al.

Summary: The COVID-19 pandemic has significantly impacted the treatment of psychiatric patients in Europe, with differences in service delivery between countries. It is important to strengthen communication and cooperation among healthcare providers to ensure effective mental health care during crises.

EUROPEAN PSYCHIATRY (2021)

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Article Medicine, Research & Experimental

Cross-National Variations in COVID-19 Mortality: The Role of Diet, Obesity and Depression

Ravi Philip Rajkumar

Summary: The study discovered that COVID-19 mortality rates were positively correlated with sugar consumption, obesity, and depression prevalence, while negatively correlated with seafood consumption. Obesity and depression, possibly related to inflammatory dysregulation, may contribute to cross-national variations in COVID-19 mortality, whereas seafood consumption could potentially have a protective effect.

DISEASES (2021)

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Review Pharmacology & Pharmacy

The Potential Role of Lithium as an Antiviral Agent against SARS-CoV-2 via Membrane Depolarization: Review and Hypothesis

Abdallah Barjas Qaswal et al.

Summary: This review proposes lithium as a potential drug to treat COVID-19 by suppressing NLRP3 inflammasome activity, inhibiting cell death, and modulating the immune system. Urgent preclinical and clinical studies are needed to prove the efficacy and safety of lithium in improving the condition of COVID-19 patients.

SCIENTIA PHARMACEUTICA (2021)

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Article Psychiatry

6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records

Maxime Taquet et al.

Summary: Our study provides evidence of significant neurological and psychiatric morbidity in the 6 months following COVID-19 infection. The risks were highest in patients with severe COVID-19. This information could assist in service planning and research priority identification.

LANCET PSYCHIATRY (2021)

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Article Public, Environmental & Occupational Health

Population-Level Disparities in COVID-19: Measuring the Independent Association of the Proportion of Black Population on COVID-19 Cases and Deaths in US Counties

Anne H. Gaglioti et al.

Summary: An ecological analysis of US counties found a positive association between the proportion of non-Hispanic Black (NHB) population and COVID-19 case and death rates, indicating higher risks in Black communities. This association remained unchanged even after adjusting for other factors, highlighting the disproportionate impact of COVID-19 on racial and ethnic minorities.

JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE (2021)

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Review Biochemistry & Molecular Biology

Is there a link between vitamin D status, SARS-CoV-2 infection risk and COVID-19 severity?

Davide Ferrari et al.

Summary: COVID-19, which emerged in December 2019, rapidly spread globally affecting individuals of different genders and ages, with severe cases more common among elderly males with comorbidities. Vitamin D has been suggested to potentially enhance immunity, reduce inflammation, and be associated with diseases affecting COVID-19 outcomes.

CELL BIOCHEMISTRY AND FUNCTION (2021)

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Article Biochemistry & Molecular Biology

Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells

Alexander Carpinteiro et al.

Summary: The acid sphingomyelinase/ceramide system plays a crucial role in cellular infection with some viruses, including SARS-CoV-2. Ambroxol has the potential to inhibit acid sphingomyelinase and prevent SARS-CoV-2 infection, making it a candidate for clinical studies in preventing COVID-19.

JOURNAL OF BIOLOGICAL CHEMISTRY (2021)

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Review Virology

Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?

Marc Desforges et al.

VIRUSES-BASEL (2020)

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Editorial Material Immunology

Using psychoneuroimmunity against COVID-19

Sung-Wan Kim et al.

BRAIN BEHAVIOR AND IMMUNITY (2020)

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Article Neurosciences

Repurposing chlorpromazine to treat COVID-19: The reCoVery study

M. Plaze et al.

ENCEPHALE-REVUE DE PSYCHIATRIE CLINIQUE BIOLOGIQUE ET THERAPEUTIQUE (2020)

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Review Multidisciplinary Sciences

Prevalence, Severity and Mortality associated with COPD and Smoking in patients with COVID-19: A Rapid Systematic Review and Meta-Analysis

Jaber S. Alqahtani et al.

PLOS ONE (2020)

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Review Psychiatry

The potential impact of COVID-19 on psychosis: A rapid review of contemporary epidemic and pandemic research

Ellie Brown et al.

SCHIZOPHRENIA RESEARCH (2020)

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Review Nutrition & Dietetics

Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths

William B. Grant et al.

NUTRIENTS (2020)

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Editorial Material Medicine, General & Internal

Covid-19: risk factors for severe disease and death

Rachel E. Jordan et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

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Article Public, Environmental & Occupational Health

Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 2019-United States, February 12-March 28, 2020

Nancy Chow et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2020)

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Article Multidisciplinary Sciences

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

David E. Gordon et al.

NATURE (2020)

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Review Psychiatry

Lithium's antiviral effects: a potential drug for CoViD-19 disease?

Andrea Murru et al.

INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS (2020)

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Review Psychiatry

Neuropsychiatric aspects of COVID-19 pandemic: A selective review

Damodharan Dinakaran et al.

ASIAN JOURNAL OF PSYCHIATRY (2020)

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Editorial Material Chemistry, Medicinal

Lithium as a candidate treatment forCOVID-19: Promises and pitfalls

Ravi Philip Rajkumar

DRUG DEVELOPMENT RESEARCH (2020)

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Article Biochemistry & Molecular Biology

Nicotine and the nicotinic cholinergic system in COVID-19

Yousef Tizabi et al.

FEBS JOURNAL (2020)

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Review Immunology

Flattening the COVID-19 Curve With Natural Killer Cell Based Immunotherapies

Marisa Market et al.

FRONTIERS IN IMMUNOLOGY (2020)

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Article Virology

Prognostic value of interleukin-6, C -reactive protein, patients with COVID-19 and procalcitonin in

Fang Liu et al.

JOURNAL OF CLINICAL VIROLOGY (2020)

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Review Infectious Diseases

The pathogenesis and treatment of the 'Cytokine Storm' in COVID-19

Qing Ye et al.

JOURNAL OF INFECTION (2020)

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Article Environmental Sciences

Baseline Chronic Comorbidity and Mortality in Laboratory-Confirmed COVID-19 Cases: Results from the PRECOVID Study in Spain

Beatriz Poblador-Plou et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020)

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Article Public, Environmental & Occupational Health

Characteristics and predictors of hospitalization and death in the first 11 122 cases with a positive RT-PCR test for SARS-CoV-2 in Denmark: a nationwide cohort

Mette Reilev et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2020)

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Article Multidisciplinary Sciences

Multimorbidity, polypharmacy, and COVID-19 infection within the UK Biobank cohort

Ross McQueenie et al.

PLOS ONE (2020)

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Letter Psychiatry

Psychotropics drugs with cationic amphiphilic properties may afford some protection against SARS- CoV-2: A mechanistic hypothesis

Jean-Marie Vaugeois

PSYCHIATRY RESEARCH (2020)

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Article Psychiatry

A COVID-19 testing and triage algorithm for psychiatric units: One hospital's response to the New York region's pandemic

Benjamin D. Brody et al.

PSYCHIATRY RESEARCH (2020)

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Article Public, Environmental & Occupational Health

Socio-economic status and COVID-19-related cases and fatalities

R. B. Hawkins et al.

PUBLIC HEALTH (2020)

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Review Psychiatry

Mortality risk from long-term treatment with antipsychotic polypharmacy vs monotherapy among adults with serious mental illness: A systematic review and meta-analysis of observational studies

Kurt Buhagiar et al.

SCHIZOPHRENIA RESEARCH (2020)

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Review Microbiology

Friends or foes? The knowns and unknowns of natural killer cell biology in COVID-19 and other coronaviruses in July 2020

Cordelia Manickam et al.

PLOS PATHOGENS (2020)

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Letter Psychiatry

Mental illnesses among COVID-19 patients: Possible immunological underpinnings

Sujita Kumar Kar et al.

ASIAN JOURNAL OF PSYCHIATRY (2020)

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Article Medicine, General & Internal

Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19 A Randomized Clinical Trial

Eric J. Lenze et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

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Article Medicine, General & Internal

Bipolar disorders

Roger S McIntyre et al.

LANCET (2020)

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Article Medicine, General & Internal

Risk Factors Associated With In-Hospital Mortality in a US National Sample of Patients With COVID-19

Ning Rosenthal et al.

JAMA NETWORK OPEN (2020)

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Review Biochemistry & Molecular Biology

Cytokine release syndrome: inhibition of pro-inflammatory cytokines as a solution for reducing COVID-19 mortality

Negar Moradian et al.

EUROPEAN CYTOKINE NETWORK (2020)

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Article Cell Biology

Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells

Alexander Carpinteiro et al.

CELL REPORTS MEDICINE (2020)

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Article Geriatrics & Gerontology

Pre-pandemic psychiatric disorders and risk of COVID-19: a UK Biobank cohort analysis

Huazhen Yang et al.

LANCET HEALTHY LONGEVITY (2020)

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Article Infectious Diseases

Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study

Bernadette Schurink et al.

LANCET MICROBE (2020)

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Article Immunology

Antipsychotic-induced immune dysfunction: A consideration for COVID-19 risk

Meghan May et al.

BRAIN, BEHAVIOR, & IMMUNITY - HEALTH (2020)

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Review Critical Care Medicine

Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19

Wentao Ni et al.

CRITICAL CARE (2020)

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Review Psychiatry

Causes of premature mortality in schizophrenia: a review of literature published in 2018

Thomas M. Laursen

CURRENT OPINION IN PSYCHIATRY (2019)

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Article Neurosciences

Physical Health Literacy and Health-related Behaviors in Patients with Psychosis

Sung-Wan Kim et al.

CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE (2019)

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Review Geriatrics & Gerontology

Benzodiazepines or related drugs and risk of pneumonia: A systematic review and meta-analysis

Guo-qing Sun et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2019)

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Review Psychiatry

Cytokine Alterations in Schizophrenia: An Updated Review

Sara Momtazmanesh et al.

FRONTIERS IN PSYCHIATRY (2019)

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Review Oncology

Race, Socioeconomic Status, and Health-Care Access Disparities in Ovarian Cancer Treatment and Mortality: Systematic Review and Meta-Analysis

Shama Karanth et al.

JNCI CANCER SPECTRUM (2019)

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Article Psychiatry

Long-term antipsychotic polypharmacy prescribing in secondary mental health care and the risk of mortality

G. Kadra et al.

ACTA PSYCHIATRICA SCANDINAVICA (2018)

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Review Psychiatry

Overview and systematic review of studies of microbiome in schizophrenia and bipolar disorder

Tanya T. Nguyen et al.

JOURNAL OF PSYCHIATRIC RESEARCH (2018)

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Editorial Material Psychiatry

Aging of the body and the brain in schizophrenia

Lisa T. Eyler et al.

SCHIZOPHRENIA RESEARCH (2018)

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Review Medicine, General & Internal

Depression

Gin S. Malhi et al.

LANCET (2018)

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Review Psychology, Clinical

Cognitive Deficits in Psychotic Disorders: A Lifespan Perspective

Julia M. Sheffield et al.

NEUROPSYCHOLOGY REVIEW (2018)

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Article Psychology, Clinical

Educational achievement in psychiatric patients and their siblings: a register-based study in 30 000 individuals in The Netherlands

W. M. Tempelaar et al.

PSYCHOLOGICAL MEDICINE (2017)

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Editorial Material Psychiatry

Reversing the downward spiral for people with severe mental illness through educational innovations

Marc de Hert et al.

WORLD PSYCHIATRY (2017)

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Article Psychiatry

Excess mortality in persons with severe mental disorders: a multilevel intervention framework and priorities for clinical practice, policy and research agendas

Nancy H. Liu et al.

WORLD PSYCHIATRY (2017)

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Article Medicine, General & Internal

Risk of pneumonia associated with incident benzodiazepine use among community-dwelling adults with Alzheimer disease

Heidi Taipale et al.

CANADIAN MEDICAL ASSOCIATION JOURNAL (2017)

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Article Psychiatry

Mortality and Cumulative Exposure to Antipsychotics, Antidepressants, and Benzodiazepines in Patients With Schizophrenia: An Observational Follow-Up Study

Jari Tiihonen et al.

AMERICAN JOURNAL OF PSYCHIATRY (2016)

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Review Public, Environmental & Occupational Health

The Relationship Between Sedatives, Sedative Strategy, and Healthcare-Associated Infection: A Systematic Review

Daniel A. Caroff et al.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2016)

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Review Clinical Neurology

Mortality and life expectancy in persons with severe unipolar depression

Thomas Munk Laursen et al.

JOURNAL OF AFFECTIVE DISORDERS (2016)

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Review Medicine, General & Internal

Schizophrenia

Michael J. Owen et al.

LANCET (2016)

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Article Psychiatry

A systematic review and meta-analysis of premature mortality in bipolar affective disorder

J. F. Hayes et al.

ACTA PSYCHIATRICA SCANDINAVICA (2015)

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Review Biochemistry & Molecular Biology

Secretory sphingomyelinase in health and disease

Johannes Kornhuber et al.

BIOLOGICAL CHEMISTRY (2015)

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Article Psychiatry

Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder

Christoph U. Correll et al.

WORLD PSYCHIATRY (2015)

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Article Psychiatry

Mortality in Mental Disorders and Global Disease Burden Implications A Systematic Review and Meta-analysis

Elizabeth Reisinger Walker et al.

JAMA PSYCHIATRY (2015)

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Article Psychiatry

Physical illness in patients with severe mental disorders. II. Barriers to care, monitoring and treatment guidelines, plus recommendations at the system and individual level

MARC DE HERT et al.

World Psychiatry (2015)

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Article Pharmacology & Pharmacy

Concomitant use of two or more antipsychotic drugs is common in Sweden

Annica Bergendal et al.

THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY (2015)

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Article Psychology, Clinical

Antipsychotic Drugs, Mood Stabilizers, and Risk of Pneumonia in Bipolar Disorder: A Nationwide Case-Control Study

Shu-Yu Yang et al.

JOURNAL OF CLINICAL PSYCHIATRY (2013)

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Article Psychiatry

Second-Generation Antipsychotic Medications and Risk of Pneumonia in Schizophrenia

Chian-Jue Kuo et al.

SCHIZOPHRENIA BULLETIN (2013)

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Article Psychiatry

Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care

Marc De Hert et al.

WORLD PSYCHIATRY (2011)

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Letter Psychology, Clinical

A 5-Year Follow-Up of Diabetes Knowledge in Persons With Serious Mental Illness and Type 2 Diabetes

Faith B. Dickerson et al.

JOURNAL OF CLINICAL PSYCHIATRY (2009)

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