☆ 4.6 Review

Psychedelic Therapy's Transdiagnostic Effects: A Research Domain Criteria (RDoC) Perspective

FRONTIERS IN PSYCHIATRY (2021)

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects

Anna M. Becker et al.

Summary: The study examined the interaction between escitalopram and psilocybin in the treatment of depression and anxiety. Escitalopram pretreatment was found to reduce certain negative effects of psilocybin, but further research is needed to fully understand the interactions between antidepressants and psilocybin in patients with psychiatric disorders.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2022)

Add to Collection
Article Neurosciences

Low-dose LSD and the stream of thought: Increased Discontinuity of Mind, Deep Thoughts and abstract flow

Isabel Wiessner et al.

Summary: The study aimed to investigate the effects of LSD on the stream of thought, revealing that LSD impacts chaos, meaning, sensation, and abstract flow, indicating a potential therapeutic window for psycholytic therapy.

PSYCHOPHARMACOLOGY (2022)

Add to Collection
Article Psychology, Clinical

Preventing substance use among Latino youth: Initial results from a multistate family-based program focused on youth academic success

Ronald B. Cox et al.

Summary: The study assessed the effects of a family-based intervention on substance use among Latino early adolescents, finding that strengthening family involvement in youths' schooling and promoting youth personal agency can prevent or reduce substance use.

AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE (2022)

Add to Collection
Article Clinical Neurology

Can pragmatic research, real-world data and digital technologies aid the development of psychedelic medicine?

Robin L. Carhart-Harris et al.

Summary: Psychedelic therapy is experiencing a major comeback, with positive regulatory assessments and substantial commercial investment. However, current confirmatory trials may not be sufficient for advancing our understanding of safety and best practice. It is suggested to supplement traditional trials with new research methods and digital solutions to support the discovery of optimal and personalized treatment protocols.

JOURNAL OF PSYCHOPHARMACOLOGY (2022)

Add to Collection
Article Medicine, General & Internal

Psychedelic perceptions: mental health service user attitudes to psilocybin therapy

Kate Corrigan et al.

Summary: The majority of mental health service users support further research into psilocybin therapy. Younger individuals, those with previous recreational psychedelic experience, and those with non-religious beliefs are more likely to have favorable attitudes towards psilocybin therapy. A minority of participants believe psychedelics are addictive and unsafe even under medical supervision.

IRISH JOURNAL OF MEDICAL SCIENCE (2022)

Add to Collection
Article Clinical Neurology

Lasting effects of a single psilocybin dose on resting-state functional connectivity in healthy individuals

Drummond E-Wen McCulloch et al.

Summary: This study evaluated the long-term effects of psilocybin on resting-state functional connectivity in healthy psychedelic-naive volunteers. The results showed that psilocybin decreased executive control network connectivity at 1 week, which predicted increased mindfulness at 3 months. This suggests that psilocybin may have lasting effects on brain connectivity and mindfulness.

JOURNAL OF PSYCHOPHARMACOLOGY (2022)

Add to Collection
Review Clinical Neurology

Psychedelics and health behaviour change

Pedro J. Teixeira et al.

Summary: Healthy behaviors have a significant impact on reducing the risk of serious diseases, leading to increased interest in interventions promoting such behaviors. The potential role of psychedelic substances like psilocybin in facilitating positive lifestyle changes is being explored, along with their mechanisms of action and research findings in health behavior change science.

JOURNAL OF PSYCHOPHARMACOLOGY (2022)

Add to Collection
Article Neurosciences

Neural Responsivity to Reward Versus Punishment Shortly After Trauma Predicts Long-Term Development of Posttraumatic Stress Symptoms

Ziv Ben-Zion et al.

Summary: This study found that PTSD severity following trauma is associated with neural functioning and risky behavior. Specifically, biased neural responsivity to positive as compared to negative motivational outcomes plays a crucial role in the development of PTSD.

BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING (2022)

Add to Collection
Article Psychiatry

The role of the gut microbiome in the development of schizophrenia

John R. Kelly et al.

Summary: Schizophrenia is a complex neurodevelopmental disorder influenced by both genetic and environmental factors. Precise regulation of neural circuitry development and microbiota-gut-brain axis signaling play crucial roles in cognitive and emotional functions. Understanding these mechanisms may lead to potential translational interventions in managing schizophrenia.

SCHIZOPHRENIA RESEARCH (2021)

Add to Collection
Editorial Material Psychiatry

The Current Status of Psychedelics in Psychiatry

David Nutt et al.

JAMA PSYCHIATRY (2021)

Add to Collection
Review Psychology, Clinical

Linking RDoC and HiTOP: A new interface for advancing psychiatric nosology and neuroscience

Giorgia Michelini et al.

Summary: The Research Domain Criteria (RDoC) and the Hierarchical Taxonomy of Psychopathology (HiTOP) are two major dimensional frameworks proposing alternative approaches to accelerate progress in studying and treating psychopathology. Their complementary strengths can be leveraged to provide more informative clinical targets and ultimately advance clinical neuroscience and psychiatric nosology.

CLINICAL PSYCHOLOGY REVIEW (2021)

Add to Collection
Article Clinical Neurology

Brain serotonin 2A receptor binding predicts subjective temporal and mystical effects of psilocybin in healthy humans

Dea Siggaard Stenbaek et al.

Summary: This study found associations between brain 5-HT2AR binding and the intensity and duration of psilocybin effects, as well as mystical experiences. The findings suggest a potential link between individual brain levels of 5-HT2AR and therapeutic outcomes in clinical studies.

JOURNAL OF PSYCHOPHARMACOLOGY (2021)

Add to Collection
Article Neurosciences

Psilocybin exerts distinct effects on resting state networks associated with serotonin and dopamine in mice

Joanes Grandjean et al.

Summary: This study investigated the effects of psilocybin on functional connectivity (FC) across the entire brain in mice, finding that psilocybin reduced FC within the ventral striatum. It was revealed that psilocybin increased FC between 5-HT-associated networks and cortical areas while decreasing FC within dopamine-associated striatal networks. These findings suggest that interactions between 5-HT- and dopamine-regulated neural networks play a role in the neural and psychological effects of psilocybin. Additionally, the study highlights how molecular expression patterns and structural connectivity information can aid in understanding pharmaco-fMRI findings.

NEUROIMAGE (2021)

Add to Collection
Article Neurosciences

Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects

Friederike Holze et al.

Summary: This study evaluated the subjective and autonomic effects of different doses of LSD in healthy subjects. It found that LSD displayed dose-proportional pharmacokinetics and dose-dependently induced subjective responses, with a ceiling effect observed for good drug effects at 100 μg. The results suggest that future LSD research may benefit from dose finding based on these findings, and that the full psychedelic effects of LSD are primarily mediated by serotonin 5-HT2A receptor activation.

NEUROPSYCHOPHARMACOLOGY (2021)

Add to Collection
Review Psychiatry

Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern-era clinical studies

Kristoffer A. A. Andersen et al.

Summary: The systematic review of modern-era clinical studies on serotonergic psychedelics drugs for mental health conditions shows promising treatment efficacy and long-lasting effects in some patients. The safety and feasibility of the studies provide important evidence for the potential of psychedelic therapy as a new treatment avenue for psychiatric conditions.

ACTA PSYCHIATRICA SCANDINAVICA (2021)

Add to Collection
Article Neurosciences

Amygdala and Insula Connectivity Changes Following Psychotherapy for Posttraumatic Stress Disorder: A Randomized Clinical Trial

Gregory A. Fonzo et al.

Summary: Exposure-based psychotherapy for PTSD patients has been shown to induce changes in brain activity patterns, including increased connectivity between the amygdala and insula, expanded connectivity with other brain regions, and weakened connections in certain areas. These changes in brain activity may serve as potential mechanisms of recovery.

BIOLOGICAL PSYCHIATRY (2021)

Add to Collection
Article Biochemistry & Molecular Biology

A Single Dose of Psilocybin Increases Synaptic Density and Decreases 5-HT2A Receptor Density in the Pig Brain

Nakul Ravi Raval et al.

Summary: This study showed that a single dose of psilocybin can lead to increased SV2A density and decreased 5-HT2AR density in the pig brain, suggesting a potential role in the antidepressant effects of psilocybin.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection
Review Clinical Neurology

Ketamine and Serotonergic Psychedelics: Common Mechanisms Underlying the Effects of Rapid-Acting Antidepressants

Bashkim Kadriu et al.

Summary: Ketamine and serotonergic psychedelics may share a common mechanism in generating rapid neuroplastic effects and affecting cortical network activity that lead to antidepressant efficacy. Despite some similarities, the connection between the psychoactive component and antidepressant efficacy of these drugs remains unclear and requires further research. The prototypic nature of ketamine research and recent progress in this area suggest a promising platform for investigating new classes of rapid-acting antidepressants.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2021)

Add to Collection
Article Multidisciplinary Sciences

A non-hallucinogenic psychedelic analogue with therapeutic potential

Lindsay P. Cameron et al.

Summary: The study identifies key structural elements of the potential therapeutic pharmacophore of ibogaine and designs tabernanthalog, a safer, non-hallucinogenic analogue of ibogaine. Tabernanthalog is found to promote neural plasticity, reduce addiction-related behavior, and produce antidepressant effects in rodents. Through careful chemical design, it is possible to modify psychedelic compounds to produce safer, non-hallucinogenic variants with therapeutic potential.

NATURE (2021)

Add to Collection
Article Neurosciences

MDMA-induced changes in within-network connectivity contradict the specificity of these alterations for the effects of serotonergic hallucinogens

Felix Mueller et al.

Summary: The study found that both serotonergic hallucinogens and non-hallucinogenic substances like MDMA can induce decreased within-network connectivity, suggesting that these alterations may not be specific to hallucinogens.

NEUROPSYCHOPHARMACOLOGY (2021)

Add to Collection
Review Pharmacology & Pharmacy

Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms

Antonio Inserra et al.

Summary: Psychedelic compounds are emerging as potential novel therapeutics in psychiatry, with their main effects mediated through the modulation of neurotransmitter systems, immunity, and neuroplasticity. Promising results suggest an opportunity for improvement in the treatment of psychiatric disorders, an area that has seen limited advancement in the past 20 years. Studies are underway to separate the psychedelic effects from the therapeutic effects of these compounds, aiming to provide more effective treatment options.

PHARMACOLOGICAL REVIEWS (2021)

Add to Collection
Article Multidisciplinary Sciences

Lysergic acid diethylamide (LSD) promotes social behavior through mTORC1 in the excitatory neurotransmission

Danilo De Gregorio et al.

Summary: Clinical studies have shown that LSD can enhance empathy and social behavior in humans. This study in male mice found that LSD promotes social behavior by potentiating glutamatergic neurotransmission in the medial prefrontal cortex through the 5-HT2A/AMPA receptors and mTOR signaling. The results suggest that activating these pathways with psychedelic drugs could be explored for treating mental disorders characterized by social behavior impairments.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Add to Collection
Review Neurosciences

The acute effects of classic psychedelics on memory in humans

C. J. Healy

Summary: Classic psychedelics dose-dependently impair memory task performance but may enhance autobiographical memory. These findings are relevant to the understanding of psychological mechanisms of action of psychedelic-assisted psychotherapy.

PSYCHOPHARMACOLOGY (2021)

Add to Collection
Review Neurosciences

Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants

Nicole L. Galvao-Coelho et al.

Summary: Classic serotonergic psychedelics show moderate to significant improvements in mood and depressive symptoms for both healthy volunteers and patients with mood disorders, with enduring effects especially notable in the longer term.

PSYCHOPHARMACOLOGY (2021)

Add to Collection
Article Pediatrics

Population vs Individual Prediction of Poor Health From Results of Adverse Childhood Experiences Screening

Jessie R. Baldwin et al.

Summary: This study suggests that while ACE scores can predict mean group differences in health outcomes, they have poor accuracy in predicting an individual's risk of later health problems. Therefore, interventions based on ACE screening are likely to be ineffective in preventing poor health outcomes.

JAMA PEDIATRICS (2021)

Add to Collection
Editorial Material Psychiatry

Psychedelics in Psychiatry-Keeping the Renaissance From Going Off the Rails

David B. Yaden et al.

Summary: The psychedelic research renaissance should focus on integrating these medications into standard care in order to progress towards effective treatment options.

JAMA PSYCHIATRY (2021)

Add to Collection
Review Neurosciences

Smartphones and the Neuroscience of Mental Health

Claire M. Gillan et al.

Summary: Improvements in understanding the neurobiological basis of mental illness have not resulted in major advances in treatment. Smartphone-based research methods have the potential to complement lab-based neuroscience research and provide rich data sets for researchers to understand the relationship between brain function and mental health.

ANNUAL REVIEW OF NEUROSCIENCE, VOL 44, 2021 (2021)

Add to Collection
Article Behavioral Sciences

Investigating the role of 5-HT2A and 5-HT2C receptor activation in the effects of psilocybin, DOI, and citalopram on marble burying in mice

Anna U. Odland et al.

Summary: This study confirmed that psychedelics acting as 5-HT2AR agonists can reduce compulsive-like digging behavior in mice, while also suggesting that both 5-HT2A and 5-HT(2C)Rs may work in parallel on this behavior. Results with psilocybin indicate that a 5-HT2R-independent mechanism may also contribute to its effect on repetitive digging behavior.

BEHAVIOURAL BRAIN RESEARCH (2021)

Add to Collection
Article Clinical Neurology

Dose-response relationships of psilocybin-induced subjective experiences in humans

Tim Hirschfeld et al.

Summary: This study aimed to investigate the dose-response relationships of subjective experiences induced by psilocybin, and found that psilocybin dose positively correlated with ratings on most factors and scales. Psilocybin intensified almost all characteristics of altered states of consciousness assessed, with challenging experiences being minimally modulated by dose.

JOURNAL OF PSYCHOPHARMACOLOGY (2021)

Add to Collection
Article Clinical Neurology

Optimal dosing for psilocybin pharmacotherapy: Considering weight-adjusted and fixed dosing approaches

Albert Garcia-Romeu et al.

Summary: The study found that the subjective effects of psilocybin were not affected by body weight when administered either on a weight-adjusted basis or as a fixed dose. The convenience and lower cost of administering psilocybin as a fixed dose outweigh any potential advantages of weight-adjusted dosing.

JOURNAL OF PSYCHOPHARMACOLOGY (2021)

Add to Collection
Article Clinical Neurology

Lysergic acid diethylamide differentially modulates the reticular thalamus, mediodorsal thalamus, and infralimbic prefrontal cortex: An in vivo electrophysiology study in male mice

Antonio Inserra et al.

Summary: The study investigates the effects of cumulative LSD doses on different neurons in the brain using in vivo extracellular single-unit recordings in adult male mice. LSD modulates firing and burst-firing activity of reticular thalamus neurons in a dose-response fashion, affecting thalamocortical relay neurons and pyramidal neurons in the prefrontal cortex. The D2 receptor antagonist haloperidol partially reverses the effects of LSD, suggesting a D-2-mediated mechanism for the modulation of thalamocortical gating.

JOURNAL OF PSYCHOPHARMACOLOGY (2021)

Add to Collection
Review Neurosciences

Cognitive and behavioural flexibility: neural mechanisms and clinical considerations

Lucina Q. Uddin

Summary: Cognitive and behavioral flexibility, critical for adapting thoughts and actions under changing circumstances, can be enhanced through cognitive training, physical activity, and bilingual experience. Brain mechanisms and functional brain networks play important roles in supporting flexibility, while it can also be compromised in various diseases.

NATURE REVIEWS NEUROSCIENCE (2021)

Add to Collection
Article Neurosciences

LSD alters dynamic integration and segregation in the human brain

Andrea Luppi et al.

Summary: Investigating the effects of LSD on brain function and subjective experience reveals that LSD increases the complexity of dynamic functional connectivity and weakens the relationship between functional and anatomical connectivity. Time-specific effects are correlated with different aspects of subjective experiences, providing a more nuanced and temporally-specific understanding of altered brain connectivity and complexity under psychedelics.

NEUROIMAGE (2021)

Add to Collection
Article Pharmacology & Pharmacy

Low Doses of Psilocybin and Ketamine Enhance Motivation and Attention in Poor Performing Rats: Evidence for an Antidepressant Property

Guy A. Higgins et al.

Summary: Studies suggest that short-term administration of high psychedelic doses of serotonergic and dissociative hallucinogens like psilocybin and ketamine might have therapeutic potential for conditions such as major depressive disorder. Experiments using low doses of ketamine and psilocybin in rats show potential benefits in improving appetite, attention accuracy, and impulsive behavior.

FRONTIERS IN PHARMACOLOGY (2021)

Add to Collection
Article Psychiatry

Development and Evaluation of a Therapist Training Program for Psilocybin Therapy for Treatment-Resistant Depression in Clinical Research

Sara J. Tai et al.

Summary: This paper describes the development and practical implementation of a therapist training program of psychological support within a current phase IIb international, multicenter, randomized controlled study of psilocybin therapy for treatment-resistant depression. The program consists of online learning, in-person training, applied clinical training, and ongoing individual mentoring. Feedback from therapists trained in the program indicated that the didactic and experiential learning helped build their conceptual understanding and skill development in the therapeutic approach.

FRONTIERS IN PSYCHIATRY (2021)

Add to Collection
Article Neurosciences

Trauma Affects Prospective Relationships Between Reward-Related Ventral Striatal and Amygdala Activation and 1-Year Future Hypo/ Mania Trajectories

Kristen L. Eckstrand et al.

Summary: This study aimed to investigate how lifetime trauma exposure influences relationships between reward neural circuitry function and the course of future affective and anxiety symptoms. The results showed that trauma exposure affects prospective relationships between markers of reward circuitry function and affective symptom trajectories. Evaluating trauma exposure is crucial in identifying neural predictors of future affective symptom course in naturalistic and treatment studies.

BIOLOGICAL PSYCHIATRY (2021)

Add to Collection
Article Neurosciences

Altered Prediction-Error Processing May Underlie Psilocybin-Induced Changes in Self-Processing

Katrin Preller

BIOLOGICAL PSYCHIATRY (2021)

Add to Collection
Article Psychiatry

Psilocybin therapy increases cognitive and neural flexibility in patients with major depressive disorder

Manoj K. Doss et al.

Summary: The study investigated the enduring effects of psilocybin therapy on cognitive and neural flexibility, finding that cognitive flexibility improved post-treatment and some neural dynamics changes were associated with changes in cognitive flexibility one week after treatment.

TRANSLATIONAL PSYCHIATRY (2021)

Add to Collection
Article Psychiatry

Psilocin, LSD, mescaline, and DOB all induce broadband desynchronization of EEG and disconnection in rats with robust translational validity

Cestmir Vejmola et al.

Summary: This study evaluated the effects of various psychedelics on EEG activity in rats, showing a decrease and desynchronization in brain activity. Different psychedelics induced subtle spatial patterns in EEG activity.

TRANSLATIONAL PSYCHIATRY (2021)

Add to Collection
Article Neurosciences

Engram cell connectivity: an evolving substrate for information storage

Tomas J. Ryan et al.

Summary: Understanding memory storage involves explaining how information is stored in the brain in a stable state, known as an engram. Recent research suggests that memory and instinct may be represented as isomorphic topological structures in the brain's microanatomical circuitry.

CURRENT OPINION IN NEUROBIOLOGY (2021)

Add to Collection
Article Psychiatry

Study Protocol for Psilocybin as a Treatment for Anorexia Nervosa: A Pilot Study

Meg J. Spriggs et al.

Summary: This study aims to assess the feasibility, brain mechanisms, and preliminary outcomes of treating anorexia nervosa with psilocybin-assisted therapy. Feedback obtained through Public Patient Involvement (PPI) and the protocol design will be crucial for shaping future Randomized Control Trials (RCTs).

FRONTIERS IN PSYCHIATRY (2021)

Add to Collection
Article Psychiatry

Self-Medication for Chronic Pain Using Classic Psychedelics: A Qualitative Investigation to Inform Future Research

Julia Bornemann et al.

Summary: By interviewing 11 individuals who self-medicate with psychedelic drugs for chronic pain, it was found that pain scores significantly improved during and after psychedelic experiences. Processes like Positive Reframing and Somatic Presence played a role in improving mental wellbeing and relationship with pain. Other strategies such as mindfulness, breathwork, and movement were also reported as helpful.

FRONTIERS IN PSYCHIATRY (2021)

Add to Collection
Review Psychiatry

Psychedelics and Other Psychoplastogens for Treating Mental Illness

Maxemiliano V. Vargas et al.

Summary: Psychedelics offer new hope for treating brain disorders due to their sustained therapeutic effects and broad potential, but face challenges in clinical scalability. Research on psychoplastogens provides insight into neural plasticity and offers a new paradigm for addressing the underlying pathophysiology of mental illness. Effectively deploying psychoplastogenic medicines at scale will be a key consideration for future development in the field.

FRONTIERS IN PSYCHIATRY (2021)

Add to Collection
Article Multidisciplinary Sciences

Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism

Marcus W. Meinhardt et al.

Summary: The study identified a common molecular pathological mechanism for both executive dysfunction and alcohol craving in alcohol-dependent patients, and proposed a personalized mGluR2 mechanism-based intervention strategy for medication development.

SCIENCE ADVANCES (2021)

Add to Collection
Article Pharmacology & Pharmacy

Effects of Ayahuasca on the Recognition of Facial Expressions of Emotions in Naive Healthy Volunteers A Pilot, Proof-of-Concept, Randomized Controlled Trial

Juliana Mendes Rocha et al.

Summary: This study found that a single dose of ayahuasca did not significantly affect the recognition of emotions in facial expressions in healthy volunteers, and had no significant impact on cardiovascular measures and brain-derived neurotrophic factor levels. Volunteers reported mainly visual effects, tranquility/relaxation, and well-being, with tolerability mainly involving nausea, gastrointestinal discomfort, and vomiting.

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2021)

Add to Collection
Article Clinical Neurology

Prediction of MDMA response in healthy humans: a pooled analysis of placebo-controlled studies

Erich Studerus et al.

Summary: The study found that, in addition to MDMA plasma concentration, personality traits and mood state can influence individual's acute physiological and psychological response to MDMA. Both pharmacological and non-pharmacological factors play a role in the response to MDMA.

JOURNAL OF PSYCHOPHARMACOLOGY (2021)

Add to Collection
Article Medicine, General & Internal

Trial of Psilocybin versus Escitalopram for Depression

Robin Carhart-Harris et al.

Summary: The study compared the efficacy of psilocybin and escitalopram in treating patients with major depressive disorder. While there was no significant difference in antidepressant effects between the two drugs at week 6, secondary outcomes generally favored psilocybin over escitalopram, though these results were not adjusted for multiple comparisons. Larger and longer trials are needed to further compare psilocybin with established antidepressants.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Add to Collection
Article Multidisciplinary Sciences

Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice

Natalie Hesselgrave et al.

Summary: Psilocybin has shown promising rapid and persistent antidepressant effects in mice, possibly through enhancing excitatory synapses in the hippocampus, independent of 5-HT2A receptor activation. Further research is needed to explore the potential combination of psychedelic compounds and 5-HT2AR antagonists for clinical utility in human depression.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Add to Collection
Article Psychology, Biological

LSD and ketanserin and their impact on the human autonomic nervous system

Sebastian Olbrich et al.

Summary: This study evaluated the effects of LSD and the serotonin 2A receptor antagonist ketanserin on the autonomic nervous system (ANS), finding that LSD mainly increased sympathetic activity while ketanserin countered this effect by increasing parasympathetic activity. Sympathetic activity was positively correlated with the psychedelic effects of LSD, providing a potential biomarker for the effectiveness of LSD in treating psychopathological conditions.

PSYCHOPHYSIOLOGY (2021)

Add to Collection
Article Psychiatry

Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder A Randomized Clinical Trial

Alan K. Davis et al.

Summary: The study showed that psilocybin therapy with psychological support is effective in treating MDD, building on previous findings in patients with cancer and depression, as well as in a nonrandomized study in patients with treatment-resistant depression.

JAMA PSYCHIATRY (2021)

Add to Collection
Article Psychiatry

Spontaneous and deliberate creative cognition during and after psilocybin exposure

N. L. Mason et al.

Summary: This study demonstrated that psilocybin can enhance creative thinking acutely while decreasing task-based creativity, and can increase the number of novel ideas seven days later. Brain imaging research indicated that the effects of psilocybin on creativity are linked to connectivity within and between networks in the default mode network.

TRANSLATIONAL PSYCHIATRY (2021)

Add to Collection
Article Pharmacology & Pharmacy

Relational Processes in Ayahuasca Groups of Palestinians and Israelis

Leor Roseman et al.

Summary: This study focuses on the impact of psychedelics in a cross-cultural context on group and individual processes. Through in-depth interviews, it was found that psychedelic ceremonies have the potential to contribute to peacebuilding by fostering unity, mutual recognition, and addressing conflict-related issues.

FRONTIERS IN PHARMACOLOGY (2021)

Add to Collection
Article Pharmacology & Pharmacy

Psychedelic Communitas: Intersubjective Experience During Psychedelic Group Sessions Predicts Enduring Changes in Psychological Wellbeing and Social Connectedness

H. Kettner et al.

Summary: This study introduces and psychometrically validates an adapted Communitas Scale to investigate psychosocial mechanisms pertinent to psychedelic ceremonies and retreats. Results show a positive relationship between participants and facilitators, and the perceived impact of emotional support, facilitating the emergence of communitas. Communitas during ceremony was significantly correlated with increases in psychological wellbeing and social connectedness.

FRONTIERS IN PHARMACOLOGY (2021)

Add to Collection
Article Psychiatry

Psilocybin: From Serendipity to Credibility?

James J. Rucker et al.

Summary: Psilocybin has a long history of non-medical use and some believe it has therapeutic potential based on early clinical trials, but larger trials are needed to confirm this. Retreat centers offering paid experiences with psilocybin truffles may be risking credibility by using early trial data for bold claims. Providing psilocybin as a paid service before proper testing could undermine ethical principles and the credibility of the field.

FRONTIERS IN PSYCHIATRY (2021)

Add to Collection
Article Medicine, General & Internal

The gut microbiome influences the bioavailability of olanzapine in rats

Sofia Cussotto et al.

Summary: The study found that the oral bioavailability of olanzapine significantly increased in rats with antibiotic-induced depletion of gut microbiota, while the bioavailability of risperidone remained unchanged. Changes in the gut microbiome may influence the pharmacokinetics of olanzapine, with the relative abundance of Alistipes significantly correlated with the AUC of olanzapine.

EBIOMEDICINE (2021)

Add to Collection
Article Biochemistry & Molecular Biology

An analog of psychedelics restores functional neural circuits disrupted by unpredictable stress

Ju Lu et al.

Summary: The study shows that TBG can reduce anxiety levels and rescue deficits in sensory processing and cognitive flexibility in mice under stress. Furthermore, TBG promotes the regrowth of excitatory neuron dendritic spines and enhances neural activity in the somatosensory cortex.

MOLECULAR PSYCHIATRY (2021)

Add to Collection
Article Neurosciences

Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo

Ling-Xiao Shao et al.

Summary: The study showed that psilocybin can induce rapid and lasting synaptic rewiring in the cortex, increasing spine size and density. This structural change may have potential implications for long-term integration of experiences and lasting beneficial actions.

NEURON (2021)

Add to Collection
Article Pharmacology & Pharmacy

Classic Psychedelic Coadministration with Lithium, but Not Lamotrigine, is Associated with Seizures: An Analysis of Online Psychedelic Experience Reports

Sandeep M. Nayak et al.

Summary: The combination of classic psychedelics with mood stabilizers, particularly lithium, may significantly increase the risk of seizures, as indicated by reports analyzed from online forums. Further research is needed to fully understand the potential risks and interactions.

PHARMACOPSYCHIATRY (2021)

Add to Collection
Article Biology

Transcriptomics-informed large-scale cortical model captures topography of pharmacological neuroimaging effects of LSD

Joshua B. Burt et al.

Summary: Psychoactive drugs like LSD can temporarily disrupt brain physiology while preserving brain structure. Research has shown that the neural and experiential effects of LSD are due to its agonism of the serotonin-2A receptor. By integrating brainwide transcriptomics with circuit modeling, this study simulated the effects of LSD on human cortical dynamics and found that serotonin-2A-mediated modulation of pyramidal-neuronal gain is a key mechanism through which LSD alters cortical functional topography. This work establishes a framework for linking molecular-level manipulations to systems-level functional alterations.

ELIFE (2021)

Add to Collection
Review Psychiatry

Perturbations in Gut Microbiota Composition in Psychiatric Disorders A Review and Meta-analysis

Viktoriya L. Nikolova et al.

Summary: This meta-analysis found that gut microbiota perturbations were associated with a transdiagnostic pattern with a depletion of certain anti-inflammatory butyrate-producing bacteria and an enrichment of pro-inflammatory bacteria in patients with depression, bipolar disorder, schizophrenia, and anxiety.

JAMA PSYCHIATRY (2021)

Add to Collection
Review Psychiatry

Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics

Cato M. H. de Vos et al.

Summary: Clinical studies suggest that psychedelics induce rapid changes in neuroplasticity mechanisms, leading to alterations in gene and protein expression, increased neurotrophic factor levels, and enhanced dendritic complexity. Repeated administration of psychedelics can directly stimulate neurogenesis and elevate BDNF mRNA levels, indicating potential long-lasting effects on brain plasticity. Future research could focus on deciphering specific cellular mechanisms activated by different psychedelics to better understand their therapeutic potential.

FRONTIERS IN PSYCHIATRY (2021)

Add to Collection
Article Psychiatry

Ceremonial Ayahuasca in Amazonian Retreats-Mental Health and Epigenetic Outcomes From a Six-Month Naturalistic Study

Simon G. D. Ruffell et al.

Summary: Recent research has shown that participants in ayahuasca ceremonies experienced a significant decrease in depression and anxiety levels, as well as improvements in self-compassion and psychometric outcomes, with some of these effects lasting for up to 6 months. Further investigation into clinical samples and the mechanistic action of ayahuasca is recommended.

FRONTIERS IN PSYCHIATRY (2021)

Add to Collection
Article Neuroimaging

Amygdala substructure volumes in Major Depressive Disorder

Darren Roddy et al.

Summary: The study identified larger right medial nuclei volumes in MDD compared to healthy controls, as well as relatively increased right compared to left whole and substructure volume ratios in MDD. This suggests that amygdala substructure volumes may be involved in the pathophysiology of depression.

NEUROIMAGE-CLINICAL (2021)

Add to Collection
Article Chemistry, Medicinal

Low Doses of LSD Acutely Increase BDNF Blood Plasma Levels in Healthy Volunteers

Nadia R. P. W. Hutten et al.

Summary: The study found that single low doses of LSD can significantly increase BDNF levels in healthy volunteers in a short period of time, providing a new direction for researching the use of LSD in patient populations.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2021)

Add to Collection
Article Chemistry, Medicinal

Transient Stimulation with Psychoplastogens Is Sufficient to Initiate Neuronal Growth

Calvin Ly et al.

Summary: Cortical neuron atrophy is a hallmark of depression, and psychoplastogens like ketamine and LSD have been shown to promote sustained growth of cortical neurons after short periods of stimulation. These psychoplastogens induce cortical neuron growth through distinct phases, with early TrkB activation and later sustained mTOR and AMPA receptor activation being crucial. It is suggested that rapidly excreted psychoplastogens may have unique advantages as neurotherapeutics compared to compounds like ketamine and LSD.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2021)

Add to Collection
Article Chemistry, Medicinal

Psilocybin-Assisted Group Therapy and Attachment: Observed Reduction in Attachment Anxiety and Influences of Attachment Insecurity on the Psilocybin Experience

Christopher S. Stauffer et al.

Summary: Attachment insecurity, measured by attachment anxiety and attachment avoidance, is an early determiner of psychopathology risk. Psilocybin-assisted psychotherapy shows potential in reducing attachment anxiety, but not attachment avoidance. Baseline attachment insecurity is correlated with the type of experiences induced by psilocybin.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2021)

Add to Collection
Article Chemistry, Medicinal

Acute and Sustained Reductions in Loss of Meaning and Suicidal Ideation Following Psilocybin-Assisted Psychotherapy for Psychiatric and Existential Distress in Life-Threatening Cancer

Stephen Ross et al.

Summary: Psilocybin-assisted psychotherapy (PAP) shows rapid and sustained improvements in depression, demoralization, and hopelessness in cancer patients. Further analysis reveals significant within-group reductions in loss of meaning and suicidal ideation following PAP treatment.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2021)

Add to Collection
Article Chemistry, Medicinal

The Subjective Effects of Psychedelics May Not Be Necessary for Their Enduring Therapeutic Effects

David E. Olson

Summary: Psychedelics have shown promise for treating neuropsychiatric disorders due to their ability to promote neural plasticity and produce rapid and sustained therapeutic effects, but evidence suggests that the subjective effects induced by these drugs may not be necessary for long-lasting changes in mood and behavior. Understanding the role of subjective effects in the therapeutic mechanisms of psychedelics will have important implications for basic neuroscience and patient access to future medicines developed from psychedelic research.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2021)

Add to Collection
Article Chemistry, Medicinal

The Subjective Effects of Psychedelics Are Necessary for Their Enduring Therapeutic Effects

David B. Yaden et al.

Summary: The subjective effects of psychedelics are crucial for their lasting benefits, accounting for the majority of their therapeutic outcomes.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2021)

Add to Collection
Article Psychology, Experimental

The entropic tongue: Disorganization of natural language under LSD

Camila Sanz et al.

Summary: The study found that language produced under the effects of LSD exhibits increased entropy and reduced semantic coherence, with features more similar to manic psychoses than schizophrenia. Machine learning classifiers were able to accurately identify speech under LSD based on non-semantic features related to language organization.

CONSCIOUSNESS AND COGNITION (2021)

Add to Collection
Review Psychology, Clinical

Defining and measuring psychological flexibility: A narrative scoping review of diverse flexibility and rigidity constructs and perspectives

Kathlyn M. Cherry et al.

Summary: Research on psychological flexibility has shown the existence of various concepts and measurement tools, including psychological flexibility, psychological inflexibility, and cognitive flexibility, with similarities in their definitions. The Personalized Psychological Flexibility Index is considered the best current measure for assessing PF.

CLINICAL PSYCHOLOGY REVIEW (2021)

Add to Collection
Article Clinical Neurology

Exploratory Controlled Study of the Migraine-Suppressing Effects of Psilocybin

Emmanuelle A. D. Schindler et al.

Summary: An exploratory study found that a single administration of psilocybin had a lasting therapeutic effect on migraine headaches, separate from its acute psychotropic effects. This highlights the importance of further investigating the clinical effects of select 5-HT2A receptor compounds in migraine and other neuropsychiatric conditions.

NEUROTHERAPEUTICS (2021)

Add to Collection
Article Neurosciences

Rapid and sustained decreases in suicidality following a single dose of ayahuasca among individuals with recurrent major depressive disorder: results from an open-label trial

Richard J. Zeifman et al.

Summary: The study aimed to examine the acute and post-acute effect of ayahuasca on suicidality among individuals with MDD. Results showed significant decreases in suicidality among individuals with suicidal tendencies at baseline after receiving ayahuasca treatment, both in the acute and post-acute stages.

PSYCHOPHARMACOLOGY (2021)

Add to Collection
Article Clinical Neurology

Transcriptional regulation in the rat prefrontal cortex and hippocampus after a single administration of psilocybin

Oskar Hougaard Jefsen et al.

Summary: The study demonstrates that psilocybin rapidly induces gene expression related to neuroplasticity, biased towards the prefrontal cortex, compared to the hippocampus. This provides further evidence for the rapid plasticity-promoting effects of psilocybin.

JOURNAL OF PSYCHOPHARMACOLOGY (2021)

Add to Collection
Article Psychiatry

Positive effects of psychedelics on depression and wellbeing scores in individuals reporting an eating disorder

M. J. Spriggs et al.

Summary: This study found that there were improvements in depressive symptoms and psychological wellbeing after using psychedelic drugs, providing supportive evidence for positive psychological aftereffects of a psychedelic experience.

EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY (2021)

Add to Collection
Article Neurosciences

Distinct acute effects of LSD, MDMA, and d-amphetamine in healthy subjects

Friederike Holze et al.

NEUROPSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Psychiatry

Comparison of the Association Between Goal-Directed Planning and Self-reported Compulsivity vs Obsessive-Compulsive Disorder Diagnosis

Claire M. Gillan et al.

JAMA PSYCHIATRY (2020)

Add to Collection
Article Psychiatry

Shared Neural Phenotypes for Mood and Anxiety Disorders A Meta-analysis of 226 Task-Related Functional Imaging Studies

Delfina Janiri et al.

JAMA PSYCHIATRY (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Psychedelics, but Not Ketamine, Produce Persistent Antidepressant-like Effects in a Rodent Experimental System for the Study of Depression

Meghan Hibicke et al.

ACS CHEMICAL NEUROSCIENCE (2020)

Add to Collection
Review Psychiatry

Psychedelics and Psychedelic-Assisted Psychotherapy

Collin M. Reiff et al.

AMERICAN JOURNAL OF PSYCHIATRY (2020)

Add to Collection
Article Neurosciences

Psilocybin Induces Time-Dependent Changes in Global Functional Connectivity

Katrin H. Preller et al.

BIOLOGICAL PSYCHIATRY (2020)

Add to Collection
Article Clinical Neurology

A single psilocybin dose is associated with long-term increased mindfulness, preceded by a proportional change in neocortical 5-HT2A receptor binding

Martin Korsbak Madsen et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Clinical Neurology

Response to ostracism in patients with chronic depression, episodic depression and borderline personality disorder a study using Cyberball

Elias Seidl et al.

JOURNAL OF AFFECTIVE DISORDERS (2020)

Add to Collection
Article Clinical Neurology

Therapeutic mechanisms of psilocybin: Changes in amygdala and prefrontal functional connectivity during emotional processing after psilocybin for treatment-resistant depression

Lea J. Mertens et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Clinical Neurology

Long-term follow-up of psilocybin-assisted psychotherapy for psychiatric and existential distress in patients with life-threatening cancer

Gabrielle Agin-Liebes et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Neurosciences

Ayahuasca's 'afterglow': improved mindfulness and cognitive flexibility in ayahuasca drinkers

A. Murphy-Beiner et al.

PSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Neurosciences

Prospective examination of synthetic 5-methoxy-N,N-dimethyltryptamine inhalation: effects on salivary IL-6, cortisol levels, affect, and non-judgment

Malin Uthaug et al.

PSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Public, Environmental & Occupational Health

Social disconnectedness, perceived isolation, and symptoms of depression and anxiety among older Americans (NSHAP): a longitudinal mediation analysis

Ziggi Ivan Santini et al.

LANCET PUBLIC HEALTH (2020)

Add to Collection
Article Multidisciplinary Sciences

Emotions and brain function are altered up to one month after a single high dose of psilocybin

Frederick S. Barrett et al.

SCIENTIFIC REPORTS (2020)

Add to Collection
Editorial Material Biochemistry & Molecular Biology

Psychedelic Psychiatry's Brave New World

David Nutt et al.

CELL (2020)

Add to Collection
Article Psychology, Clinical

Positive and negative valence systems in major depression have distinct clinical features, response to antidepressants, and relationships with immunomarkers

Gustavo C. Medeiros et al.

DEPRESSION AND ANXIETY (2020)

Add to Collection
Review Neurosciences

Rethinking Therapeutic Strategies for Anorexia Nervosa: Insights From Psychedelic Medicine and Animal Models

Claire J. Foldi et al.

FRONTIERS IN NEUROSCIENCE (2020)

Add to Collection
Review Neurosciences

Reward Circuitry and Motivational Deficits in Social Anxiety Disorder: What Can Be Learned From Mouse Models?

Corinne N. Carlton et al.

FRONTIERS IN NEUROSCIENCE (2020)

Add to Collection
Review Clinical Neurology

Reviewing the Potential of Psychedelics for the Treatment of PTSD

Erwin Krediet et al.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Psychiatry

Learning to Let Go: A Cognitive-Behavioral Model of How Psychedelic Therapy Promotes Acceptance

Max Wolff et al.

FRONTIERS IN PSYCHIATRY (2020)

Add to Collection
Article Neurosciences

Broadening Your Mind to Include Others: The relationship between serotonergic psychedelic experiences and maladaptive narcissism

Valerie van Mulukom et al.

PSYCHOPHARMACOLOGY (2020)

Add to Collection
Review Anesthesiology

Chronic pain and psychedelics: a review and proposed mechanism of action

Joel P. Castellanos et al.

REGIONAL ANESTHESIA AND PAIN MEDICINE (2020)

Add to Collection
Review Clinical Neurology

Efficacy of psychedelic treatments on depressive symptoms: A meta-analysis

Bruno Romeo et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Biochemistry & Molecular Biology

A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia

Andrew D. Krystal et al.

NATURE MEDICINE (2020)

Add to Collection
Article Neurosciences

Psilocybin acutely alters the functional connectivity of the claustrum with brain networks that support perception, memory, and attention

Frederick S. Barrett et al.

NEUROIMAGE (2020)

Add to Collection
Article Neurosciences

Psilocybin and LSD have no long-lasting effects in an animal model of alcohol relapse

Marcus W. Meinhardt et al.

NEUROPSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Neurosciences

Me, myself, bye: regional alterations in glutamate and the experience of ego dissolution with psilocybin

N. L. Mason et al.

NEUROPSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Psychiatry

Subcortical Brain Volume, Regional Cortical Thickness, and Cortical Surface Area Across Disorders: Findings From the ENIGMA ADHD, ASD, and OCD Working Groups

Premika S. W. Boedhoe et al.

AMERICAN JOURNAL OF PSYCHIATRY (2020)

Add to Collection
Review Psychology, Clinical

Historic psychedelic drug trials and the treatment of anxiety disorders

Neil M. Weston et al.

DEPRESSION AND ANXIETY (2020)

Add to Collection
Article Psychiatry

Post-Psychedelic Reductions in Experiential Avoidance Are Associated With Decreases in Depression Severity and Suicidal Ideation

Richard J. Zeifman et al.

FRONTIERS IN PSYCHIATRY (2020)

Add to Collection
Article Medicine, General & Internal

Longitudinal Assessment of Mental Health Disorders and Comorbidities Across 4 Decades Among Participants in the Dunedin Birth Cohort Study

Avshalom Caspi et al.

JAMA NETWORK OPEN (2020)

Add to Collection
Article Clinical Neurology

Changes in inflammatory biomarkers are related to the antidepressant effects of Ayahuasca

Nicole Leite Galvao-Coelho et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor

Kuglae Kim et al.

CELL (2020)

Add to Collection
Article Neurosciences

Updating the dynamic framework of thought: Creativity and psychedelics

Manesh Girn et al.

NEUROIMAGE (2020)

Add to Collection
Review Clinical Neurology

Psychedelic Treatments for Psychiatric Disorders: A Systematic Review and Thematic Synthesis of Patient Experiences in Qualitative Studies

Joost J. Breeksema et al.

CNS DRUGS (2020)

Add to Collection
Article Multidisciplinary Sciences

LSD-induced increases in social adaptation to opinions similar to one's own are associated with stimulation of serotonin receptors

Patricia Duerler et al.

SCIENTIFIC REPORTS (2020)

Add to Collection
Review Neurosciences

Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders

Franz X. Vollenweider et al.

NATURE REVIEWS NEUROSCIENCE (2020)

Add to Collection
Article Neurosciences

Serotonergic psychedelics LSD & psilocybin increase the fractal dimension of cortical brain activity in spatial and temporal domains

Thomas F. Varley et al.

NEUROIMAGE (2020)

Add to Collection
Article Psychiatry

Hallucinations Under Psychedelics and in the Schizophrenia Spectrum: An Interdisciplinary and Multiscale Comparison

Pantelis Leptourgos et al.

SCHIZOPHRENIA BULLETIN (2020)

Add to Collection
Editorial Material Psychiatry

RDoCat 10: changing the discourse for psychopathology

Charles A. Sanislow

WORLD PSYCHIATRY (2020)

Add to Collection
Article Multidisciplinary Sciences

The Acute Effects of the Atypical Dissociative Hallucinogen Salvinorin A on Functional Connectivity in the Human Brain

Manoj K. Doss et al.

SCIENTIFIC REPORTS (2020)

Add to Collection
Editorial Material Neurosciences

Carving Out New Transdiagnostic Dimensions for Research in Mental Health

Claire M. Gillan et al.

BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING (2020)

Add to Collection
Review Immunology

Psychedelics as a novel approach to treating autoimmune conditions

Caitlin Thompson et al.

IMMUNOLOGY LETTERS (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Psychedelics as an emerging novel intervention in the treatment of substance use disorder: a review

Alec J. DiVito et al.

MOLECULAR BIOLOGY REPORTS (2020)

Add to Collection
Article Neurosciences

Acute social isolation evokes midbrain craving responses similar to hunger

Livia Tomova et al.

NATURE NEUROSCIENCE (2020)

Add to Collection
Article Pharmacology & Pharmacy

The Effects of Daytime Psilocybin Administration on Sleep: Implications for Antidepressant Action

Daniela Dudysova et al.

FRONTIERS IN PHARMACOLOGY (2020)

Add to Collection
Review Pharmacology & Pharmacy

Psychedelic-assisted therapy for functional neurological disorders: A theoretical framework and review of prior reports

Benjamin Stewart et al.

PHARMACOLOGY RESEARCH & PERSPECTIVES (2020)

Add to Collection
Article Medicine, General & Internal

Psilocybin-assisted group therapy for demoralized older long-term AIDS survivor men: An open-label safety and feasibility pilot study

Brian T. Anderson et al.

ECLINICALMEDICINE (2020)

Add to Collection
Review Psychology, Clinical

Post-acute psychological effects of classical serotonergic psychedelics: a systematic review and meta-analysis

Simon B. Goldberg et al.

PSYCHOLOGICAL MEDICINE (2020)

Add to Collection
Article Psychology, Biological

Neural network models for DMT-induced visual hallucinations

Michael M. Schartner et al.

NEUROSCIENCE OF CONSCIOUSNESS (2020)

Add to Collection
Review Psychology, Clinical

The potential synergistic effects between psychedelic administration and nature contact for the improvement of mental health

Sam Gandy et al.

HEALTH PSYCHOLOGY OPEN (2020)

Add to Collection
Article Neurosciences

Intrinsic Connectivity Networks in the Self- and Other-Referential Processing

Gennady G. Knyazev et al.

FRONTIERS IN HUMAN NEUROSCIENCE (2020)

Add to Collection
Review Pharmacology & Pharmacy

Psychedelics and virtual reality: parallels and applications

Jacob S. Aday et al.

THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Psychology, Clinical

A Meta-Analysis of Placebo-Controlled Trials of Psychedelic-Assisted Therapy

Jason B. Luoma et al.

JOURNAL OF PSYCHOACTIVE DRUGS (2020)

Add to Collection
Review Pharmacology & Pharmacy

Psychedelic treatment of functional neurological disorder: a systematic review

Matthew Butler et al.

THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Rostral Anterior Cingulate Thickness Predicts the Emotional Psilocybin Experience

Candace R. Lewis et al.

BIOMEDICINES (2020)

Add to Collection
Review Psychology, Clinical

Exploring the case for research on incorporating psychedelics within interventions for borderline personality disorder

Richard J. Zeifman et al.

JOURNAL OF CONTEXTUAL BEHAVIORAL SCIENCE (2020)

Add to Collection
Review Otorhinolaryngology

Automated assessment of psychiatric disorders using speech: A systematic review

Daniel M. Low et al.

LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY (2020)

Add to Collection
Article Psychology, Clinical

Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety

Alan K. Davis et al.

JOURNAL OF CONTEXTUAL BEHAVIORAL SCIENCE (2020)

Add to Collection
Article Neurosciences

Preliminary Report on the Effects of a Low Dose of LSD on Resting-State Amygdala Functional Connectivity

Anya K. Bershad et al.

BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING (2020)

Add to Collection
Review Neurosciences

Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease

Martin G. Codagnone et al.

BIOLOGICAL PSYCHIATRY (2019)

Add to Collection
Article Psychology, Clinical

Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial

Fernanda Palhano-Fontes et al.

PSYCHOLOGICAL MEDICINE (2019)

Add to Collection
Article Clinical Neurology

Recreational use of psychedelics is associated with elevated personality trait openness: Exploration of associations with brain serotonin markers

David Erritzoe et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2019)

Add to Collection
Article Neurosciences

Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels

Martin K. Madsen et al.

NEUROPSYCHOPHARMACOLOGY (2019)

Add to Collection
Review Pharmacology & Pharmacy

Gut Reactions: Breaking Down Xenobiotic-Microbiome Interactions

Gerard Clarke et al.

PHARMACOLOGICAL REVIEWS (2019)

Add to Collection
Article Neurosciences

Psilocybin lacks antidepressant-like effect in the Flinders Sensitive Line rat

Oskar Jefsen et al.

ACTA NEUROPSYCHIATRICA (2019)

Add to Collection
Article Clinical Neurology

Cessation and reduction in alcohol consumption and misuse after psychedelic use

Albert Garcia-Romeu et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2019)

Add to Collection
Article Medicine, Research & Experimental

Psychedelic medicine: The biology underlying the persisting psychedelic effects

K. P. C. Kuypers

MEDICAL HYPOTHESES (2019)

Add to Collection
Article Neurosciences

Dynamical exploration of the repertoire of brain networks at rest is modulated by psilocybin

Louis-David Lord et al.

NEUROIMAGE (2019)

Add to Collection
Review Psychiatry

Transdiagnostic psychiatry: a systematic review

Paolo Fusar-Poli et al.

WORLD PSYCHIATRY (2019)

Add to Collection
Article Multidisciplinary Sciences

Mapping human microbiome drug metabolism by gut bacteria and their genes

Michael Zimmermann et al.

NATURE (2019)

Add to Collection
Review Pharmacology & Pharmacy

REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics

R. L. Carhart-Harris et al.

PHARMACOLOGICAL REVIEWS (2019)

Add to Collection
Review Psychology, Clinical

Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels

Emanuele Felice Osimo et al.

PSYCHOLOGICAL MEDICINE (2019)

Add to Collection
Article Anatomy & Morphology

A Role for the Claustrum in Salience Processing?

Jared B. Smith et al.

FRONTIERS IN NEUROANATOMY (2019)

Add to Collection
Review Psychiatry

A Literature Overview of Virtual Reality (VR) in Treatment of Psychiatric Disorders: Recent Advances and Limitations

Mi Jin Park et al.

FRONTIERS IN PSYCHIATRY (2019)

Add to Collection
Article Neurosciences

Resting state functional connectivity and cognitive task-related activation of the human claustrum

Samuel R. Krimmel et al.

NEUROIMAGE (2019)

Add to Collection
Article Neurosciences

Psilocybin-assisted mindfulness training modulates self-consciousness and brain default mode network connectivity with lasting effects

Lukasz Smigielski et al.

NEUROIMAGE (2019)

Add to Collection
Review Physiology

THE MICROBIOTA-GUT-BRAIN AXIS

John F. Cryan et al.

PHYSIOLOGICAL REVIEWS (2019)

Add to Collection
Review Physiology

THE NEUROSCIENCE OF DRUG REWARD AND ADDICTION

Nora D. Volkow et al.

PHYSIOLOGICAL REVIEWS (2019)

Add to Collection
Review Clinical Neurology

Classical psychedelics for the treatment of depression and anxiety: A systematic review

Silvia Muttoni et al.

JOURNAL OF AFFECTIVE DISORDERS (2019)

Add to Collection
Article Medicine, Research & Experimental

5-HT2 receptor activation alleviates airway inflammation and structural remodeling in a chronic mouse asthma model

Thomas W. Flanagan et al.

LIFE SCIENCES (2019)

Add to Collection
Article Multidisciplinary Sciences

Consciousness-specific dynamic interactions of brain integration and functional diversity

Andrea I. Luppi et al.

NATURE COMMUNICATIONS (2019)

Add to Collection
Article Multidisciplinary Sciences

Activation of 5-HT2 Receptors Reduces Inflammation in Vascular Tissue and Cholesterol Levels in High-Fat Diet-Fed Apolipoprotein E Knockout Mice

Thomas W. Flanagan et al.

SCIENTIFIC REPORTS (2019)

Add to Collection
Article Multidisciplinary Sciences

Neural correlates of the DMT experience assessed with multivariate EEG

Christopher Timmermann et al.

SCIENTIFIC REPORTS (2019)

Add to Collection
Article Multidisciplinary Sciences

Characterization and prediction of acute and sustained response to psychedelic psilocybin in a mindfulness group retreat

Lukasz Smigielski et al.

SCIENTIFIC REPORTS (2019)

Add to Collection
Article Pharmacology & Pharmacy

The Impact of Ayahuasca on Suicidality: Results From a Randomized Controlled Trial

Richard J. Zeifman et al.

FRONTIERS IN PHARMACOLOGY (2019)

Add to Collection
Article Neurosciences

Common Dysfunction of Large-Scale Neurocognitive Networks Across Psychiatric Disorders

Zhiqiang Sha et al.

BIOLOGICAL PSYCHIATRY (2019)

Add to Collection
Article Neurosciences

Trait Openness and serotonin 2A receptors in healthy volunteers: A positron emission tomography study

Dea Siggaard Stenbaek et al.

HUMAN BRAIN MAPPING (2019)

Add to Collection
Article Clinical Neurology

Abnormal functional connectivity under somatosensory stimulation in migraine: a multi-frequency magnetoencephalography study

Jing Ren et al.

JOURNAL OF HEADACHE AND PAIN (2019)

Add to Collection
Review Clinical Neurology

Emotional processing in functional neurological disorder: a review, biopsychosocial model and research agenda

Susannah Pick et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2019)

Add to Collection
Article Neurosciences

Ayahuasca improves emotion dysregulation in a community sample and in individuals with borderline-like traits

Elisabet Dominguez-Clave et al.

PSYCHOPHARMACOLOGY (2019)

Add to Collection
Article Neurosciences

The effects of microdose LSD on time perception: a randomised, double-blind, placebo-controlled trial

Steliana Yanakieva et al.

PSYCHOPHARMACOLOGY (2019)

Add to Collection
Article Psychiatry

Acute effects of ayahuasca in a juvenile non-human primate model of depression

Flavia S. da Silva et al.

BRAZILIAN JOURNAL OF PSYCHIATRY (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Chronic, Intermittent Microdoses of the Psychedelic N,N-Dimethyltryptamine (DMT) Produce Positive Effects on Mood and Anxiety in Rodents

Lindsay P. Cameron et al.

ACS CHEMICAL NEUROSCIENCE (2019)

Add to Collection
Article Environmental Sciences

From Egoism to Ecoism: Psychedelics Increase Nature Relatedness in a State-Mediated and Context-Dependent Manner

Hannes Kettner et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2019)

Add to Collection
Article Psychiatry

Detecting relapse in youth with psychotic disorders utilizing patient-generated and patient-contributed digital data from Facebook

M. L. Birnbaum et al.

NPJ SCHIZOPHRENIA (2019)

Add to Collection
Article Psychology, Multidisciplinary

Modulation of Serum Brain-Derived Neurotrophic Factor by a Single Dose of Ayahuasca: Observation From a Randomized Controlled Trial

Raissa Nobrega de Almeida et al.

FRONTIERS IN PSYCHOLOGY (2019)

Add to Collection
Article Multidisciplinary Sciences

Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation

R. N. Moda-Sava et al.

SCIENCE (2019)

Add to Collection
Article Clinical Neurology

Psilocybin-occasioned mystical-type experience in combination with meditation and other spiritual practices produces enduring positive changes in psychological functioning and in trait measures of prosocial attitudes and behaviors

Roland R. Griffiths et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2018)

Add to Collection
Article Neurosciences

Increased amygdala responses to emotional faces after psilocybin for treatment-resistant depression

Leor Roseman et al.

NEUROPHARMACOLOGY (2018)

Add to Collection
Article Neurosciences

Double-blind comparison of the two hallucinogens psilocybin and dextromethorphan: similarities and differences in subjective experiences

Theresa M. Carbonaro et al.

PSYCHOPHARMACOLOGY (2018)

Add to Collection
Article Neurosciences

Psilocybin with psychological support improves emotional face recognition in treatment-resistant depression

J. B. Stroud et al.

PSYCHOPHARMACOLOGY (2018)

Add to Collection
Editorial Material Neurosciences

Psychedelics and connectedness

R. L. Carhart-Harris et al.

PSYCHOPHARMACOLOGY (2018)

Add to Collection
Article Neurosciences

Psilocybin with psychological support for treatment-resistant depression: six-month follow-up

R. L. Carhart-Harris et al.

PSYCHOPHARMACOLOGY (2018)

Add to Collection
Article Biochemistry & Molecular Biology

Effects of N,N-Dimethyltryptamine on Rat Behaviors Relevant to Anxiety and Depression

Lindsay P. Cameron et al.

ACS CHEMICAL NEUROSCIENCE (2018)

Add to Collection
Article Neurosciences

Face Perception in Social Anxiety: Visuocortical Dynamics Reveal Propensities for Hypervigilance or Avoidance

Lisa M. McTeague et al.

BIOLOGICAL PSYCHIATRY (2018)

Add to Collection
Article Clinical Neurology

Psilocybin modulates functional connectivity of the amygdala during emotional face discrimination

O. Grimm et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2018)

Add to Collection
Article Neurosciences

Role of the 5-HT2A Receptor in Self- and Other-Initiated Social Interaction in Lysergic Acid Diethylamide-Induced States: A Pharmacological fMRI Study

Katrin H. Preller et al.

JOURNAL OF NEUROSCIENCE (2018)

Add to Collection
Article Clinical Neurology

Psychedelic therapy for smoking cessation: Qualitative analysis of participant accounts

Tehseen Noorani et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2018)

Add to Collection
Article Clinical Neurology

Increased nature relatedness and decreased authoritarian political views after psilocybin for treatment-resistant depression

Taylor Lyons et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2018)

Add to Collection
Article Clinical Neurology

Psychedelics and the essential importance of context

Robin L. Carhart-Harris et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2018)

Add to Collection
Review Neurosciences

The abuse potential of medical psilocybin according to the 8 factors of the Controlled Substances Act

Matthew W. Johnson et al.

NEUROPHARMACOLOGY (2018)

Add to Collection
Review Behavioral Sciences

Serotonergic psychedelics and personality: A systematic review of contemporary research

Jose Carlos Bouso et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2018)

Add to Collection
Review Clinical Neurology

Serotonergic hallucinogens in the treatment of anxiety and depression in patients suffering from a life-threatening disease: A systematic review

Simon Reiche et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2018)

Add to Collection
Article Neurosciences

The hidden therapist: evidence for a central role of music in psychedelic therapy

Mendel Kaelen et al.

PSYCHOPHARMACOLOGY (2018)

Add to Collection
Article Multidisciplinary Sciences

Analysis of shared heritability in common disorders of the brain

Verneri Anttila et al.

SCIENCE (2018)

Add to Collection
Article Psychiatry

Prediction of psychosis across protocols and risk cohorts using automated language analysis

Cheryl M. Corcoran et al.

WORLD PSYCHIATRY (2018)

Add to Collection
Article Cell Biology

Psychedelics Promote Structural and Functional Neural Plasticity

Calvin Ly et al.

CELL REPORTS (2018)

Add to Collection
Article Psychiatry

Aberrant salience network functional connectivity in auditory verbal hallucinations: a first episode psychosis sample

Pavan Kumar Mallikarjun et al.

TRANSLATIONAL PSYCHIATRY (2018)

Add to Collection
Review Pharmacology & Pharmacy

Neuroendocrine Associations Underlying the Persistent Therapeutic Effects of Classic Serotonergic Psychedelics

Emmanuelle A. D. Schindler et al.

FRONTIERS IN PHARMACOLOGY (2018)

Add to Collection
Review Pharmacology & Pharmacy

Unifying Theories of Psychedelic Drug Effects

Link R. Swanson

FRONTIERS IN PHARMACOLOGY (2018)

Add to Collection
Article Pharmacology & Pharmacy

The Psychedelic Debriefing in Alcohol Dependence Treatment: Illustrating Key Change Phenomena through Qualitative Content Analysis of Clinical Sessions

Elizabeth M. Nielson et al.

FRONTIERS IN PHARMACOLOGY (2018)

Add to Collection
Article Pharmacology & Pharmacy

Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression

Leor Roseman et al.

FRONTIERS IN PHARMACOLOGY (2018)

Add to Collection
Article Psychiatry

Cortisol Modulation by Ayahuasca in Patients With Treatment Resistant Depression and Healthy Controls

Ana C. de Menezes Galvao et al.

FRONTIERS IN PSYCHIATRY (2018)

Add to Collection
Article Neurosciences

Double-blind comparison of the two hallucinogens psilocybin and dextromethorphan: effects on cognition

Frederick S. Barrett et al.

PSYCHOPHARMACOLOGY (2018)

Add to Collection
Review Psychiatry

Neuroscientifically Informed Formulation and Treatment Planning for Patients With Obsessive-Compulsive Disorder A Review

Darin D. Dougherty et al.

JAMA PSYCHIATRY (2018)

Add to Collection
Review Pharmacology & Pharmacy

Efficacy, tolerability, and safety of serotonergic psychedelics for the management of mood, anxiety, and substance-use disorders: a systematic review of systematic reviews

Rafael G. dos Santos et al.

EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2018)

Add to Collection
Article Behavioral Sciences

How the human brain introspects about one's own episodes of cognitive control

David Soto et al.

CORTEX (2018)

Add to Collection
Article Biology

Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor

Katrin H. Preller et al.

ELIFE (2018)

Add to Collection
Article Pharmacology & Pharmacy

Predicting Responses to Psychedelics: A Prospective Study

Eline C. H. M. Haijen et al.

FRONTIERS IN PHARMACOLOGY (2018)

Add to Collection
Review Neurosciences

Hallucinogen Persisting Perception Disorder: Etiology, Clinical Features, and Therapeutic Perspectives

Giovanni Martinotti et al.

BRAIN SCIENCES (2018)

Add to Collection
Article Psychology, Biological

Dimensions of consciousness and the psychedelic state

Tim Bayne et al.

NEUROSCIENCE OF CONSCIOUSNESS (2018)

Add to Collection
Review Psychiatry

Psychedelics as anti-inflammatory agents

Thomas W. Flanagan et al.

INTERNATIONAL REVIEW OF PSYCHIATRY (2018)

Add to Collection
Review Psychiatry

Psychedelics and music: neuroscience and therapeutic implications

Frederick S. Barrett et al.

INTERNATIONAL REVIEW OF PSYCHIATRY (2018)

Add to Collection
Article Clinical Neurology

Assessing the Psychedelic After-Glow in Ayahuasca Users: Post-Acute Neurometabolic and Functional Connectivity Changes Are Associated with Enhanced Mindfulness Capacities

Frederic Sampedro et al.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2017)

Add to Collection
Article Clinical Neurology

Effect of Psilocybin on Empathy and Moral Decision-Making

Thomas Pokorny et al.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2017)

Add to Collection
Review Clinical Neurology

Reward processing and mood-related symptoms: An RDoC and translational neuroscience perspective

Robin Nusslock et al.

JOURNAL OF AFFECTIVE DISORDERS (2017)

Add to Collection
Article Clinical Neurology

Lifetime experience with (classic) psychedelics predicts pro-environmental behavior through an increase in nature relatedness

Matthias Forstmann et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2017)

Add to Collection
Review Clinical Neurology

Serotonin and brain function: a tale of two receptors

R. L. Carhart-Harris et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2017)

Add to Collection
Review Neurosciences

THE NEURAL UNDERPINNINGS OF COGNITIVE FLEXIBILITY AND THEIR DISRUPTION IN PSYCHOTIC ILLNESS

James A. Waltz

NEUROSCIENCE (2017)

Add to Collection
Article Clinical Neurology

Impulsivity and aggression mediate regional brain responses in Borderline Personality Disorder: An fMRI study

Paul H. Soloff et al.

PSYCHIATRY RESEARCH-NEUROIMAGING (2017)

Add to Collection
Review Endocrinology & Metabolism

Cortisol stress reactivity across psychiatric disorders: A systematic review and meta-analysis

Jelle V. Zorn et al.

PSYCHONEUROENDOCRINOLOGY (2017)

Add to Collection
Article Neurosciences

Dreamlike effects of LSD on waking imagery in humans depend on serotonin 2A receptor activation

Rainer Kraehenmann et al.

PSYCHOPHARMACOLOGY (2017)

Add to Collection
Article Multidisciplinary Sciences

A dedicated network for social interaction processing in the primate brain

J. Sliwa et al.

SCIENCE (2017)

Add to Collection
Review Neurosciences

Six Years of Research on the National Institute of Mental Health's Research Domain Criteria (RDoC) Initiative: A Systematic Review

Dean Carcone et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2017)

Add to Collection
Review Psychiatry

An Integrated Neuroscience Perspective on Formulation and Treatment Planning for Posttraumatic Stress Disorder An Educational Review

David A. Ross et al.

JAMA PSYCHIATRY (2017)

Add to Collection
Editorial Material Psychiatry

Allostasis and the Epigenetics of Brain and Body Health Over the Life Course The Brain on Stress

Bruce S. McEwen

JAMA PSYCHIATRY (2017)

Add to Collection
Article Psychiatry

Acute effects of LSD on amygdala activity during processing of fearful stimuli in healthy subjects

F. Mueller et al.

TRANSLATIONAL PSYCHIATRY (2017)

Add to Collection
Review Psychiatry

The Endless Trip among the nPS Users: Psychopathology and Psychopharmacology in the Hallucinogen-Persisting Perception Disorder. A Systematic Review

Laura Orsolini et al.

FRONTIERS IN PSYCHIATRY (2017)

Add to Collection
Article Multidisciplinary Sciences

The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro

Jose A. Morales-Garcia et al.

SCIENTIFIC REPORTS (2017)

Add to Collection
Article Multidisciplinary Sciences

Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms

Robin L. Carhart-Harris et al.

SCIENTIFIC REPORTS (2017)

Add to Collection
Article Psychology, Clinical

A Physician's Attempt to Self-Medicate Bipolar Depression with N,N-Dimethyltryptamine (DMT)

Tanida Brown et al.

JOURNAL OF PSYCHOACTIVE DRUGS (2017)

Add to Collection
Review Behavioral Sciences

What big data can do for treatment in psychiatry

Claire M. Gillan et al.

CURRENT OPINION IN BEHAVIORAL SCIENCES (2017)

Add to Collection
Article Pharmacology & Pharmacy

Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide in Healthy Subjects

Patrick C. Dolder et al.

CLINICAL PHARMACOKINETICS (2017)

Add to Collection
Article Psychology, Multidisciplinary

Three Approaches to Understanding and Classifying Mental Disorder: ICD-11, DSM-5, and the National Institute of Mental Health's Research Domain Criteria (RDoC)

Lee Anna Clark et al.

PSYCHOLOGICAL SCIENCE IN THE PUBLIC INTEREST (2017)

Add to Collection
Article Psychology, Multidisciplinary

Patients' Accounts of Increased Connectedness and Acceptance After Psilocybin for Treatment-Resistant Depression

Rosalind Watts et al.

JOURNAL OF HUMANISTIC PSYCHOLOGY (2017)

Add to Collection
Article Psychiatry

Identification of Common Neural Circuit Disruptions in Cognitive Control Across Psychiatric Disorders

Lisa M. McTeague et al.

AMERICAN JOURNAL OF PSYCHIATRY (2017)

Add to Collection
Article Neurosciences

Amygdala Reactivity and Anterior Cingulate Habituation Predict Posttraumatic Stress Disorder Symptom Maintenance After Acute Civilian Trauma

Jennifer S. Stevens et al.

BIOLOGICAL PSYCHIATRY (2017)

Add to Collection
Review Pharmacology & Pharmacy

Ayahuasca, dimethyltryptamine, and psychosis: a systematic review of human studies

Rafael G. dos Santos et al.

THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY (2017)

Add to Collection
Article Psychiatry

Neural correlates of conversion disorder: overview and meta-analysis of neuroimaging studies on motor conversion disorder

Markus Boeckle et al.

BMC PSYCHIATRY (2016)

Add to Collection
Article Biochemistry & Molecular Biology

Increased Global Functional Connectivity Correlates with LSD-Induced Ego Dissolution

Enzo Tagliazucchi et al.

CURRENT BIOLOGY (2016)

Add to Collection
Review Chemistry, Medicinal

Dopamine Targeting Drugs for the Treatment of Schizophrenia: Past, Present and Future

Peng Li et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2016)

Add to Collection
Article Neurosciences

Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus

Pauline Luczynski et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2016)

Add to Collection
Article Clinical Neurology

LSD modulates music-induced imagery via changes in parahippocampal connectivity

Mendel Kaelen et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2016)

Add to Collection
Article Clinical Neurology

The role of habit in compulsivity

Claire M. Gillan et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2016)

Add to Collection
Editorial Material Clinical Neurology

Compulsivity-A new trans-diagnostic research domain for the Roadmap for Mental Health Research in Europe (ROAMER) and Research Domain Criteria (RDoC) initiatives

N. A. Fineberg et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2016)

Add to Collection
Article Neurosciences

LSD-Induced Entropic Brain Activity Predicts Subsequent Personality Change

A. V. Lebedev et al.

HUMAN BRAIN MAPPING (2016)

Add to Collection
Article Pharmacology & Pharmacy

Antidepressant Effects of a Single Dose of Ayahuasca in Patients With Recurrent Depression A SPECT Study

Rafael Faria Sanches et al.

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2016)

Add to Collection
Article Endocrinology & Metabolism

Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects

P. Strajhar et al.

JOURNAL OF NEUROENDOCRINOLOGY (2016)

Add to Collection
Review Psychiatry

Establishing moderators and biosignatures of antidepressant response in clinical care (EMBARC): Rationale and design

Madhukar H. Trivedi et al.

JOURNAL OF PSYCHIATRIC RESEARCH (2016)

Add to Collection
Article Psychiatry

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

John R. Kelly et al.

JOURNAL OF PSYCHIATRIC RESEARCH (2016)

Add to Collection
Review Clinical Neurology

Psychedelics in the treatment of unipolar mood disorders: a systematic review

James J. H. Rucker et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2016)

Add to Collection
Article Clinical Neurology

Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial

Roland R. Griffiths et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2016)

Add to Collection
Article Clinical Neurology

Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial

Stephen Ross et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2016)

Add to Collection
Review Neurosciences

Mind-wandering as spontaneous thought: a dynamic framework

Kalina Christoff et al.

NATURE REVIEWS NEUROSCIENCE (2016)

Add to Collection
Review Biochemistry & Molecular Biology

The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis?

Roman M. Stilling et al.

NEUROCHEMISTRY INTERNATIONAL (2016)

Add to Collection
Article Neurosciences

LSD Acutely Impairs Fear Recognition and Enhances Emotional Empathy and Sociality

Patrick C. Dolder et al.

NEUROPSYCHOPHARMACOLOGY (2016)

Add to Collection
Article Pharmacology & Pharmacy

The hallucinogen D-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors

Danilo De Gregorio et al.

PHARMACOLOGICAL RESEARCH (2016)

Add to Collection
Article Multidisciplinary Sciences

Effects of serotonin 2A/1A receptor stimulation on social exclusion processing

Katrin H. Preller et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Add to Collection
Article Multidisciplinary Sciences

Neural correlates of the LSD experience revealed by multimodal neuroimaging

Robin L. Carhart-Harris et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Add to Collection
Article Psychology, Clinical

The paradoxical psychological effects of lysergic acid diethylamide (LSD)

R. L. Carhart-Harris et al.

PSYCHOLOGICAL MEDICINE (2016)

Add to Collection
Article Psychology, Biological

RDoC: Translating promise into progress

Christopher J. Patrick et al.

PSYCHOPHYSIOLOGY (2016)

Add to Collection
Article Psychiatry

Regulation of prefrontal cortex myelination by the microbiota

A. E. Hoban et al.

TRANSLATIONAL PSYCHIATRY (2016)

Add to Collection
Article Psychiatry

Cytokine production capacity in depression and anxiety

N. Vogelzangs et al.

TRANSLATIONAL PSYCHIATRY (2016)

Add to Collection
Article Neurosciences

The Endogenous Hallucinogen and Trace Amine N,N-Dimethyltryptamine (DMT) Displays Potent Protective Effects against Hypoxia via Sigma-1 Receptor Activation in Human Primary iPSC-Derived Cortical Neurons and Microglia-Like Immune Cells

Attila Szabo et al.

FRONTIERS IN NEUROSCIENCE (2016)

Add to Collection
Review Psychology, Clinical

Neurobiological model of the persistence of anorexia nervosa

Joanna E. Steinglass et al.

JOURNAL OF EATING DISORDERS (2016)

Add to Collection
Review Pharmacology & Pharmacy

Psychedelics

David E. Nichols

PHARMACOLOGICAL REVIEWS (2016)

Add to Collection
Article Psychiatry

Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study

Robin L. Carhart-Harris et al.

LANCET PSYCHIATRY (2016)

Add to Collection
Review Behavioral Sciences

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

S. M. O'Mahony et al.

BEHAVIOURAL BRAIN RESEARCH (2015)

Add to Collection
Article Pharmacology & Pharmacy

Effect of Psilocin on Extracellular Dopamine and Serotonin Levels in the Mesoaccumbens and Mesocortical Pathway in Awake Rats

Yuichi Sakashita et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2015)

Add to Collection
Review Neurosciences

Depressive Rumination, the Default-Mode Network, and the Dark Matter of Clinical Neuroscience

J. Paul Hamilton et al.

BIOLOGICAL PSYCHIATRY (2015)

Add to Collection
Article Neurosciences

Acute Effects of Lysergic Acid Diethylamide in Healthy Subjects

Yasmin Schmid et al.

BIOLOGICAL PSYCHIATRY (2015)

Add to Collection
Letter Neurosciences

Adult Hippocampal Neurogenesis Is Regulated by the Microbiome

Ebere S. Ogbonnaya et al.

BIOLOGICAL PSYCHIATRY (2015)

Add to Collection
Article Neurosciences

Psilocybin-Induced Decrease in Amygdala Reactivity Correlates with Enhanced Positive Mood in Healthy Volunteers

Rainer Kraehenmann et al.

BIOLOGICAL PSYCHIATRY (2015)

Add to Collection
Article Immunology

Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

Lieve Desbonnet et al.

BRAIN BEHAVIOR AND IMMUNITY (2015)

Add to Collection
Review Neurosciences

Memory engram storage and retrieval

Susumu Tonegawa et al.

CURRENT OPINION IN NEUROBIOLOGY (2015)

Add to Collection
Article Clinical Neurology

A review of the current nomenclature for psychotropic agents and an introduction to the Neuroscience-based Nomenclature

Joseph Zohar et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2015)

Add to Collection
Article Neurosciences

Finding the self by losing the self: Neural correlates of ego-dissolution under psilocybin

Alexander V. Lebedev et al.

HUMAN BRAIN MAPPING (2015)

Add to Collection
Article Psychology, Biological

Abnormal reward functioning across substance use disorders and major depressive disorder: Considering reward as a transdiagnostic mechanism

Arielle R. Baskin-Sommers et al.

INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY (2015)

Add to Collection
Article Psychology, Biological

Asymmetrical frontal cortical activity associated with differential risk for mood and anxiety disorder symptoms: An RDoC perspective

Robin Nusslock et al.

INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY (2015)

Add to Collection
Review Psychiatry

Collective unconscious: How gut microbes shape human behavior

Timothy G. Dinan et al.

JOURNAL OF PSYCHIATRIC RESEARCH (2015)

Add to Collection
Article Neurosciences

Elevated cognitive control over reward processing in recovered female patients with anorexia nervosa

Stefan Ehrlich et al.

JOURNAL OF PSYCHIATRY & NEUROSCIENCE (2015)

Add to Collection
Article Clinical Neurology

Psilocybin-assisted treatment for alcohol dependence: A proof-of-concept study

Michael P. Bogenschutz et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2015)

Add to Collection
Article Neurosciences

Host microbiota constantly control maturation and function of microglia in the CNS

Daniel Erny et al.

NATURE NEUROSCIENCE (2015)

Add to Collection
Article Psychiatry

Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report

Flavia de L. Osorio et al.

REVISTA BRASILEIRA DE PSIQUIATRIA (2015)

Add to Collection
Review Neurosciences

Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

John R. Kelly et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2015)

Add to Collection
Article Behavioral Sciences

Neural sensitivity to social reward and punishment anticipation in social anxiety disorder

Henk R. Cremers et al.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2015)

Add to Collection
Review Pharmacology & Pharmacy

The role of serotonin 5-HT2A receptors in memory and cognition

Gongliang Zhang et al.

FRONTIERS IN PHARMACOLOGY (2015)

Add to Collection
Review Immunology

Psychedelics and immunomodulation: novel approaches and therapeutic opportunities

Attila Szabo

FRONTIERS IN IMMUNOLOGY (2015)

Add to Collection
Article Medicine, General & Internal

Anorexia nervosa

Janet Treasure et al.

NATURE REVIEWS DISEASE PRIMERS (2015)

Add to Collection
Article Clinical Neurology

LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: A qualitative study of acute and sustained subjective effects

Peter Gasser et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2015)

Add to Collection
Article Multidisciplinary Sciences

The Psychedelic State Induced by Ayahuasca Modulates the Activity and Connectivity of the Default Mode Network

Fernanda Palhano-Fontes et al.

PLOS ONE (2015)

Add to Collection
Article Neurosciences

Dimensional psychiatry: reward dysfunction and depressive mood across psychiatric disorders

Claudia Haegele et al.

PSYCHOPHARMACOLOGY (2015)

Add to Collection
Article Neurosciences

LSD enhances suggestibility in healthy volunteers

R. L. Carhart-Harris et al.

PSYCHOPHARMACOLOGY (2015)

Add to Collection
Article Psychology, Multidisciplinary

Integrating NIMH Research Domain Criteria (RDoC) into depression research

Mary L. Woody et al.

CURRENT OPINION IN PSYCHOLOGY (2015)

Add to Collection
Article Psychiatry

Switch to mania after ayahuasca consumption in a man with bipolar disorder: a case report

Alejandro G. Szmulewicz et al.

INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS (2015)

Add to Collection
Review Biochemistry & Molecular Biology

Individualized Medicine from Prewomb to Tomb

Eric J. Topol

CELL (2014)

Add to Collection
Article Clinical Neurology

Safety and Efficacy of Lysergic Acid Diethylamide-Assisted Psychotherapy for Anxiety Associated With Life-threatening Diseases

Peter Gasser et al.

JOURNAL OF NERVOUS AND MENTAL DISEASE (2014)

Add to Collection
Article Clinical Neurology

Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction

Matthew W. Johnson et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2014)

Add to Collection
Article Multidisciplinary Sciences

Homological scaffolds of brain functional networks

G. Petri et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2014)

Add to Collection
Letter Biochemistry & Molecular Biology

Microbiota is essential for social development in the mouse

L. Desbonnet et al.

MOLECULAR PSYCHIATRY (2014)

Add to Collection
Article Neurosciences

Chronic LSD alters gene expression profiles in the mPFC relevant to schizophrenia

David A. Martin et al.

NEUROPHARMACOLOGY (2014)

Add to Collection
Article Neurosciences

Altered Resting-State Functional Connectivity of Basolateral and Centromedial Amygdala Complexes in Posttraumatic Stress Disorder

Vanessa M. Brown et al.

NEUROPSYCHOPHARMACOLOGY (2014)

Add to Collection
Article Multidisciplinary Sciences

Psychedelic N,N-Dimethyltryptamine and 5-Methoxy-N,N-Dimethyltryptamine Modulate Innate and Adaptive Inflammatory Responses through the Sigma-1 Receptor of Human Monocyte-Derived Dendritic Cells

Attila Szabo et al.

PLOS ONE (2014)

Add to Collection
Article Cell Biology

The gut microbiota influences blood-brain barrier permeability in mice

Viorica Braniste et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Add to Collection
Review Behavioral Sciences

Frontostriatal circuits and the development of bulimia nervosa

Laura A. Berner et al.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2014)

Add to Collection
Article Psychology, Clinical

Immunological Effects of Ayahuasca in Humans

Rafael Guimaraes dos Santos

JOURNAL OF PSYCHOACTIVE DRUGS (2014)

Add to Collection
Letter Psychology, Multidisciplinary

Hallucinogens - don't choose ignorance

Laura Oxley

PSYCHOLOGIST (2014)

Add to Collection
Review Neurosciences

Evidence for a Dysregulated Immune System in the Etiology of Psychiatric Disorders

Sinead M. Gibney et al.

JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2013)

Add to Collection
Article Psychiatry

Disrupted amygdala-prefrontal functional connectivity in civilian women with posttraumatic stress disorder

Jennifer S. Stevens et al.

JOURNAL OF PSYCHIATRIC RESEARCH (2013)

Add to Collection
Article Medicine, General & Internal

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Jordan W. Smoller et al.

LANCET (2013)

Add to Collection
Article Neurosciences

A Translational Rodent Assay of Affective Biases in Depression and Antidepressant Therapy

Sarah A. Stuart et al.

NEUROPSYCHOPHARMACOLOGY (2013)

Add to Collection
Review Behavioral Sciences

Emotional valence modulates brain functional abnormalities in depression: Evidence from a meta-analysis of fMRI studies

Nynke A. Groenewold et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2013)

Add to Collection
Article Multidisciplinary Sciences

Psychedelics and Mental Health: A Population Study

Teri S. Krebs et al.

PLOS ONE (2013)

Add to Collection
Article Multidisciplinary Sciences

Serotonin 5-HT2A Receptor Activation Blocks TNF-α Mediated Inflammation In Vivo

Felix Nau et al.

PLOS ONE (2013)

Add to Collection
Article Neurosciences

Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning

Briony J. Catlow et al.

EXPERIMENTAL BRAIN RESEARCH (2013)

Add to Collection
Article Psychiatry

Anxiety disorders and inflammation in a large adult cohort

N. Vogelzangs et al.

TRANSLATIONAL PSYCHIATRY (2013)

Add to Collection
Review Psychology, Multidisciplinary

The induction of synaesthesia with chemical agents: a systematic review

David P. Luke et al.

FRONTIERS IN PSYCHOLOGY (2013)

Add to Collection
Article Neurosciences

Psilocybin Biases Facial Recognition, Goal-Directed Behavior, and Mood State Toward Positive Relative to Negative Emotions Through Different Serotonergic Subreceptors

Michael Kometer et al.

BIOLOGICAL PSYCHIATRY (2012)

Add to Collection
Article Clinical Neurology

A Bayesian account of 'hysteria'

Mark J. Edwards et al.

BRAIN (2012)

Add to Collection
Article Psychiatry

Implications for psychedelic-assisted psychotherapy: functional magnetic resonance imaging study with psilocybin

R. L. Carhart-Harris et al.

BRITISH JOURNAL OF PSYCHIATRY (2012)

Add to Collection
Article Neurosciences

Domain general and domain preferential brain regions associated with different types of task switching: A Meta-Analysis

Chobok Kim et al.

HUMAN BRAIN MAPPING (2012)

Add to Collection
Review Clinical Neurology

Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings

Gabriel S. Dichter et al.

JOURNAL OF NEURODEVELOPMENTAL DISORDERS (2012)

Add to Collection
Article Clinical Neurology

Lysergic acid diethylamide (LSD) for alcoholism: meta-analysis of randomized controlled trials

Teri S. Krebs et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2012)

Add to Collection
Article Multidisciplinary Sciences

Prediction of Psilocybin Response in Healthy Volunteers

Erich Studerus et al.

PLOS ONE (2012)

Add to Collection
Article Multidisciplinary Sciences

Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin

Robin L. Carhart-Harris et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Add to Collection
Editorial Material Behavioral Sciences

The social brain meets neuroimaging

Robin I. M. Dunbar

TRENDS IN COGNITIVE SCIENCES (2012)

Add to Collection
Review Psychology, Experimental

Genuine and drug-induced synesthesia: A comparison

Christopher Sinke et al.

CONSCIOUSNESS AND COGNITION (2012)

Add to Collection
Article Psychiatry

Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer

Charles S. Grob et al.

ARCHIVES OF GENERAL PSYCHIATRY (2011)

Add to Collection
Article Clinical Neurology

Acute, subacute and long-term subjective effects of psilocybin in healthy humans: a pooled analysis of experimental studies

Erich Studerus et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2011)

Add to Collection
Article Clinical Neurology

Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness

Katherine A. MacLean et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2011)

Add to Collection
Review Neurosciences

Serotonergic regulation of neuronal excitability in the prefrontal cortex

Rodrigo Andrade

NEUROPHARMACOLOGY (2011)

Add to Collection
Article Multidisciplinary Sciences

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

Javier A. Bravo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Add to Collection
Article Multidisciplinary Sciences

Normal gut microbiota modulates brain development and behavior

Rochellys Diaz Heijtza et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Add to Collection
Editorial Material Psychiatry

Research Domain Criteria (RDoC): Toward a New Classification Framework for Research on Mental Disorders

Thomas Insel et al.

AMERICAN JOURNAL OF PSYCHIATRY (2010)

Add to Collection
Article Clinical Neurology

The default-mode, ego-functions and free-energy: a neurobiological account of Freudian ideas

R. L. Carhart-Harris et al.

BRAIN (2010)

Add to Collection
Article Behavioral Sciences

Neural correlates of rumination in depression

Rebecca E. Cooney et al.

COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE (2010)

Add to Collection
Article Neurosciences

Htr2a gene and 5-HT2A receptor expression in the cerebral cortex studied using genetically modified mice

Elaine T. Weber et al.

FRONTIERS IN NEUROSCIENCE (2010)

Add to Collection
Article Biochemistry & Molecular Biology

Effects of Psilocybe argentipes on Marble-Burying Behavior in Mice

Yoshihiro Matsushima et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2009)

Add to Collection
Review Pharmacology & Pharmacy

Neuroplasticity as a target for the pharmacotherapy of anxiety disorders, mood disorders, and schizophrenia

John H. Krystal et al.

DRUG DISCOVERY TODAY (2009)

Add to Collection
Article Multidisciplinary Sciences

The brain's default network - Anatomy, function, and relevance to disease

Randy L. Buckner et al.

YEAR IN COGNITIVE NEUROSCIENCE 2008 (2008)

Add to Collection
Article Pharmacology & Pharmacy

Serotonin 5-Hydroxytryptamine2A Receptor Activation Suppresses Tumor Necrosis Factor-α-Induced Inflammation with Extraordinary Potency

Bangning Yu et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)

Add to Collection
Review Clinical Neurology

Human hallucinogen research: guidelines for safety

M. W. Johnson et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2008)

Add to Collection
Article Multidisciplinary Sciences

Identification of a serotonin/glutamate receptor complex implicated in psychosis

Javier Gonzalez-Maeso et al.

NATURE (2008)

Add to Collection
Article Neurosciences

Pharmacological modulation of the neural basis underlying inhibition of return (IOR) in the human 5-HT2A agonist and NMDA antagonist model of psychosis

Joerg Daumann et al.

PSYCHOPHARMACOLOGY (2008)

Add to Collection
Review Psychology, Multidisciplinary

Rethinking Rumination

Susan Nolen-Hoeksema et al.

PERSPECTIVES ON PSYCHOLOGICAL SCIENCE (2008)

Add to Collection
Review Neurosciences

Stress, depression, and neuroplasticity: A convergence of mechanisms

Christopher Pittenger et al.

NEUROPSYCHOPHARMACOLOGY (2008)

Add to Collection
Review Psychiatry

Functional neuroimaging of anxiety: A meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia

Amit Etkin et al.

AMERICAN JOURNAL OF PSYCHIATRY (2007)

Add to Collection
Article Neurosciences

Amygdala-prefrontal disconnection in borderline personality disorder

Antonia S. New et al.

NEUROPSYCHOPHARMACOLOGY (2007)

Add to Collection
Article Clinical Neurology

Prepulse inhibition of the startle reflex and its attentional modulation in the human S-ketamine and N,N-dimethyltryptamine (DMT) models of psychosis

K. Heekeren et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2007)

Add to Collection
Article Neurosciences

Hallucinogens recruit specific cortical 5-HT2A receptor-mediated signaling pathways to affect behavior

Javier Gonzalez-Maeso et al.

NEURON (2007)

Add to Collection
Article Clinical Neurology

Effects of psilocybin on time perception and temporal control of behaviour in humans

Marc Wittmann et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2007)

Add to Collection
Article Psychology, Clinical

Safety, tolerability, and efficacy of psilocybin in 9 patients with obsessive-compulsive disorder

Francisco A. Moreno et al.

JOURNAL OF CLINICAL PSYCHIATRY (2006)

Add to Collection
Article Neurosciences

Resolving emotional conflict: A role for the rostral anterior cingulate cortex in modulating activity in the amygdala

Amit Etkin et al.

NEURON (2006)

Add to Collection
Article Neurosciences

Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance

R. R. Griffiths et al.

PSYCHOPHARMACOLOGY (2006)

Add to Collection
Article Neurosciences

Using psilocybin to investigate the relationship between attention, working memory, and the serotonin 1A and 2A receptors

OL Carter et al.

JOURNAL OF COGNITIVE NEUROSCIENCE (2005)

Add to Collection
Article Neurosciences

Distinct temporal phases in the behavioral pharmacology of LSD:: dopamine D2 receptor-mediated effects in the rat and implications for psychosis

D Marona-Lewicka et al.

PSYCHOPHARMACOLOGY (2005)

Add to Collection
Article Neurosciences

Acute psychological and physiological effects of psilocybin in healthy humans: a double-blind, placebo-controlled dose-effect study

F Hasler et al.

PSYCHOPHARMACOLOGY (2004)

Add to Collection
Review Pharmacology & Pharmacy

Hallucinogens

DE Nichols

PHARMACOLOGY & THERAPEUTICS (2004)

Add to Collection
Article Neurosciences

Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice

N Sudo et al.

JOURNAL OF PHYSIOLOGY-LONDON (2004)

Add to Collection
Review Psychiatry

Psychosis as a state of aberrant salience: A framework linking biology, phenomenology, and pharmacology in schizophrenia

S Kapur

AMERICAN JOURNAL OF PSYCHIATRY (2003)

Add to Collection
Article Neurosciences

A single dose of lysergic acid diethylamide influences gene expression patterns within the mammalian brain

CD Nichols et al.

NEUROPSYCHOPHARMACOLOGY (2002)

Add to Collection
Webinars Posters Questions Hubs Funding Journals Papers Connect Collections Reviewers About Us FAQs Mobile App Privacy Policy Terms of Use
© Peeref 2019-2024. All rights reserved.