Progress on the Function and Application of Thymosin β4

Thymosin beta 4 (T beta 4) is a multifunctional and widely distributed peptide that plays a pivotal role in several physiological and pathological processes in the body, namely, increasing angiogenesis and proliferation and inhibiting apoptosis and inflammation. Moreover, T beta 4 is effectively utilized for several indications in animal experiments or clinical trials, such as myocardial infarction and myocardial ischemia-reperfusion injury, xerophthalmia, liver and renal fibrosis, ulcerative colitis and colon cancer, and skin trauma. Recent studies have reported the potential application of T beta 4 and its underlying mechanisms. The present study reveals the progress regarding functions and applications of T beta 4.

Automated summary

Thymosin beta 4 (Tβ4) is a multifunctional peptide that plays a key role in physiological processes such as angiogenesis and proliferation, as well as inhibiting apoptosis and inflammation. It is effectively utilized in various indications and there is ongoing research on its potential applications and mechanisms.