Journal
INFECTION AND DRUG RESISTANCE
Volume 15, Issue -, Pages 167-170Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/IDR.S347066
Keywords
COVID-19; SARS-CoV-2; Chryseobacterium indologenes; resistance
Categories
Funding
- Ministry of Science and Technology [109-2221-E-194-038-MY3, 110-2314-B-075A-011]
- Taichung Veterans General Hospital [TCVGH-1103901C, TCVGH-1103901D]
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A case report is presented of a COVID-19 patient who developed carbapenem-resistant Chryseobacterium indologenes bacteremia, with the detection of bla(CcrA) which is reported for the first time. Antimicrobial resistance is a challenge to global health during the COVID-19 pandemic, and further study and surveillance of underlying mechanisms are needed.
We report a COVID-19 case with carbapenem resistant Chryseobacterium indologenes bacteremia. Whole genome sequencing identified the presence of bla(IND-2), bla(CIA) and bla(CcrA). To our knowledge, this is the first report of Chryseobacterium indologenes complicating COVID-19 and the detection of bla(CcrA) in C. indologenes. The presence of bla(CcrA) in Chryseobacterium was overlooked previously may related to substantial sequence divergence with the original allele in Bacteroides fragilis. Antimicrobial resistance (AMR) is a challenge to global health in the age of COVID-19 pandemic. Further study and surveillance of underlying mechanisms is needed.
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