Journal
FRONTIERS IN GENETICS
Volume 12, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fgene.2021.763159
Keywords
web portal; type 2 diabetes; coronary heart disease; venous thromboembolism; polygenic risk sore; finhealth 2017 study; P5 study; precision population health
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Funding
- Yrjoe Jahnsson Foundation the Diabetes Research Foundation Finnish Foundation for Cardiovascular Research
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The method allows for personalized genetic risk information to be communicated to Finnish individuals through a secure web portal, enabling them to manage their own health. Additionally, it offers healthcare professionals a way to utilize polygenic risk scores as a preventive tool in patient care.
We present a method for communicating personalized genetic risk information to citizens and their physicians using a secure web portal. We apply the method for 3,177 Finnish individuals in the P5 Study where estimates of genetic and absolute risk, based on genetic and clinical risk factors, of future disease are reported to study participants, allowing individuals to participate in managing their own health. Our method facilitates using polygenic risk score as a personalized tool to estimate a person's future disease risk while offering a way for health care professionals to utilize the polygenic risk scores as a preventive tool in patient care.
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