Related references
Note: Only part of the references are listed.Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162
Dieter Moosmayer et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2021)
Lipid peroxidation and ferroptosis: The role of GSH and GPx4
Fulvio Ursini et al.
FREE RADICAL BIOLOGY AND MEDICINE (2020)
Role of GPX4 in ferroptosis and its pharmacological implication
Tobias M. Seibt et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems
Isabelle Rohn et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2019)
GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues
Matilde Maiorino et al.
ANTIOXIDANTS & REDOX SIGNALING (2018)
Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis
Irina Ingold et al.
CELL (2018)
Organisms with alternative genetic codes resolve unassigned codons via mistranslation and ribosomal rescue
Natalie Jing Ma et al.
ELIFE (2018)
Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center
Giorgio Cozza et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy
Alexei P. Kudin et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Selenocysteine Insertion at a Predefined UAG Codon in a Release Factor 1 (RF1)-depleted Escherichia coli Host Strain Bypasses Species Barriers in Recombinant Selenoprotein Translation
Qing Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
Vasanthi S. Viswanathan et al.
NATURE (2017)
Generation of phospho-ubiquitin variants by orthogonal translation reveals codon skipping
Susanna George et al.
FEBS LETTERS (2016)
Selenocysteine oxidation in glutathione peroxidase catalysis: an MS-supported quantum mechanics study
Laura Orian et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Recoding the Genetic Code with Selenocysteine
Markus J. Broecker et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Jose Pedro Friedmann Angeli et al.
NATURE CELL BIOLOGY (2014)
Random Single Amino Acid Deletion Sampling Unveils Structural Tolerance and the Benefits of Helical Registry Shift on GFP Folding and Structure
James A. J. Arpino et al.
STRUCTURE (2014)
Selenium and selenocysteine: roles in cancer, health, and development
Dolph L. Hatfield et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Glutathione peroxidases
Regina Brigelius-Flohe et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
Genomically Recoded Organisms Expand Biological Functions
Marc J. Lajoie et al.
SCIENCE (2013)
Selenoproteins-What unique properties can arise with selenocysteine in place of cysteine?
Elias S. J. Arner
EXPERIMENTAL CELL RESEARCH (2010)
Catalytic mechanisms and specificities of glutathione peroxidases: Variations of a basic scheme
Stefano Toppo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
Mitochondrial glutathione peroxidase 4 disruption causes male infertility
Manuela Schneider et al.
FASEB JOURNAL (2009)
ACEMD: Accelerating Biomolecular Dynamics in the Microsecond Time Scale
M. J. Harvey et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2009)
Titration and conditional knockdown of the prfB gene in Escherichia coli: Effects on growth and overproduction of the recombinant mammalian selenoprotein thioredoxin reductase
Olle Rengby et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2007)
Tagging recombinant proteins with a Sel-tag for purification, labeling with electrophilic compounds or radiolabeling with C-11
Qing Cheng et al.
NATURE PROTOCOLS (2006)
Selenocysteine in proteins -: properties and biotechnological use
L Johansson et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2005)
The nuclear form of phospholipid hydroperoxide glutathione peroxidase is a protein thiol peroxidase contributing to sperm chromatin stability
M Conrad et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Exploiting the 21st amino acid -: purifying and labeling proteins by selenolate targeting
L Johansson et al.
NATURE METHODS (2004)
Assessment of production conditions for efficient use of Escherichia coli in high-yield heterologous recombinant selenoprotein synthesis
O Rengby et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2004)
The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults
LJ Yant et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Male fertility is linked to the selenoprotein phospholipid hydroperoxide glutathione peroxidase
C Foresta et al.
BIOLOGY OF REPRODUCTION (2002)
How selenium has altered our understanding of the genetic code
DL Hatfield et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Further development and validation of empirical scoring functions for structure-based binding affinity prediction
RX Wang et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2002)
PHGPx and spermatogenesis
A Roveri et al.
BIOFACTORS (2001)
The Protein Data Bank
HM Berman et al.
NUCLEIC ACIDS RESEARCH (2000)