Journal
ORTHOPAEDIC SURGERY
Volume 13, Issue 8, Pages 2289-2300Publisher
WILEY
DOI: 10.1111/os.13159
Keywords
Acetabular anteversion; Adult spinal deformity; Proximal junction failure; ROC analysis; Thoracic kyphosis
Categories
Ask authors/readers for more resources
In adult spinal deformity patients, immediate thoracic kyphosis and acetabular anteversion are significantly correlated with proximal junctional failure postoperatively. Patients with acetabular anteversion <= 13 degrees have significantly restricted hip motion and higher incidence of PJF. Patients with postoperative TK >= 28.1 degrees have a significantly higher risk of developing PJF.
Objectives To investigate whether the immediate thoracic kyphosis (TK) and acetabular anteversion (AA) postoperatively are correlated with proximal junctional failure (PJF) in adult spinal deformity (ASD) patients underwent surgical treatment. Methods This is a retrospective study. Following institutional ethics approval, a total of 57 patients (49 Female, eight Male) with ASD underwent surgery fused to sacroiliac bone (S1, S2, or ilium) from March 2014 to January 2019 were included. All of those patients were followed up for at least 2 years. Demographic, radiographic and surgical data were recorded. The maximum range of flexion motion (F-ROM) and extension motion (E-ROM) actively of hip joints was measured and recorded at pre- and postoperation. The sum of F-ROM and E-ROM was defined as the range of hip motion (H-ROM). Receiver operating characteristic (ROC) curve analysis was used to obtain the cut off value of parameters for PJF. A Kaplan-Meier curve and log-rank test were used to analyze the differences in PJF-free survival. Results In all, 14 patients developed PJF during follow-up. Comparisons between patients with and without PJF showed significant differences in immediate TK (P < 0.001) and AA (P = 0.027) postoperatively. ROC curve analysis determined an optimal threshold of 13 degrees for immediate AA postoperatively (sensitivity = 74.3%, specificity = 85.7%, area under the ROC curve [AUC] = 0.806, 95% CI [0.686-0.926]). Nineteen patients with post-AA <= 13 degrees were assigned into the observational group, and 38 patients with post-AA >13 degrees were being as the control group. Patients in the observational group had smaller H-ROM (P = 0.016) and F-ROM (P < 0.001), but much larger E-ROM (P < 0.001). There were 10 patients showing PJF in the observational group and four in the control group (10/9 vs 4/34, P < 0.001). PJF-free survival time significantly decreased in the observational group (P = 0.001, log-rank test). Furthermore, patients in the observational group had much larger TK (post-TK, P = 0.015). The optimal threshold for post-TK (sensitivity = 85.7%, specificity = 76.7%; AUC = 0.823, 95% CI [0.672-0.974]) was 28.1 degrees after the ROC curve was analyzed. In the observational group, those patients with post-TK >= 28.1 degrees had significantly higher incidence of PJF (9/2 vs 1/7, P < 0.001) than those with post-TK < 28.1 degrees. Moreover, PJF-free survival time in those patients significantly decreased (P = 0.001, log-rank test). Conclusions ASD patients with acetabular anteversion of <= 13 degrees at early postoperation may suffer significantly restricted hip motion and much higher incidence of PJF during follow-up, moreover, in those patients, postoperative TK >= 28.1 degrees would be a significant risk factor for PJF developing.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available