4.6 Article

Perspective: Balance Assessments in Progressive Supranuclear Palsy: Lessons Learned

Journal

FRONTIERS IN NEUROLOGY
Volume 13, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fneur.2022.801291

Keywords

progressive supranuclear palsy; balance; posturography; wearable sensors; gait

Funding

  1. National Centerfor Advancing Translational Sciences, National Institutes of Health [R01-HD100383]
  2. NIH NC-NM4R Pilot Project Grant [KL2TR002370]
  3. Collins Medical Trust to MD, and the NIH [P2CHD086844]

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This study reviewed the methodology of previous balance studies in PSP and discussed the feasibility of objective balance assessment in PSP. Lessons learned and future approaches were highlighted.
Many studies have examined aspects of balance in progressive supranuclear palsy (PSP), but guidance on the feasibility of standardized objective balance assessments and balance scales in PSP is lacking. Balance tests commonly used in Parkinson's disease often cannot be easily administered or translated to PSP. Here we briefly review methodology in prior studies of balance in PSP; then we focus on feasibility by presenting our experience with objective balance assessment in PSP-Richardson syndrome and PSP-parkinsonism during a crossover rTMS intervention trial. We highlight lessons learned, safety considerations, and future approaches for objective balance assessment in PSP.

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