☆ 4.8 Article

Enhanced Immune Responses by Virus-Mimetic Polymeric Nanostructures Against Infectious Diseases

FRONTIERS IN IMMUNOLOGY (2022)

Related references

Note: Only part of the references are listed.

Article Chemistry, Physical

A polymeric co-assembly of subunit vaccine with polyoxometalates induces enhanced immune responses

Xinpei Li et al.

Summary: By co-assembling {Mo72Fe30} with Mycobacterium bovis antigens, enhanced humoral and cellular immune responses in mice post-vaccination can be achieved. The anti-inflammatory factor IL-10 gradually increases after 2 weeks and returns to normal levels by the 5th week. The balance between proinflammatory cytokines and anti-inflammatory factors indicates that the immune system can be activated early in infection, secreting acute inflammatory factors for host defense and anti-inflammatory factors for immune protection through antigens carried by supra-particles.

NANO RESEARCH (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Enhancing Immunity with Nanomedicine: Employing Nanoparticles to Harness the Immune System

Catia T. Perciani et al.

Summary: The use of engineered nanoparticles has shown promise in enhancing vaccine efficacy and host immune responses to viral and tumor antigens. By harnessing the properties of nanoparticles, it may be possible to overcome current obstacles in vaccinology and oncology.

ACS NANO (2021)

Add to Collection

Review Pharmacology & Pharmacy

Self-assembled mRNA vaccines

Jeonghwan Kim et al.

Summary: mRNA vaccines, emerging as front-runners in the COVID-19 vaccine race, utilize advancements in RNA technology, vaccinology, and nanotechnology to design self-assembled nanoparticles for vaccine delivery, showing tremendous promise and readiness for clinical use.

ADVANCED DRUG DELIVERY REVIEWS (2021)

Add to Collection

Review Biotechnology & Applied Microbiology

Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers

Saghi Nooraei et al.

Summary: Virus-like particles (VLPs) are virus-derived structures without genetic material, able to self-assemble and mimic viruses, utilized in candidate vaccines and successful applications in targeted drug delivery and gene therapy. Modifying the surface of VLPs for increased specificity and longevity in specific cells or tissues may enhance their future use.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Novel approaches for vaccine development

Makda S. Gebre et al.

Summary: Vaccines are crucial for global health, with traditional methods being successful in many cases but facing challenges such as persistent infections and emerging pathogens. Novel technologies like nucleic acid and viral vector vaccines have the potential to revolutionize vaccine development.

CELL (2021)

Add to Collection

Article Multidisciplinary Sciences

Adjuvanting a subunit COVID-19 vaccine to induce protective immunity

Prabhu S. Arunachalam et al.

Summary: This study demonstrated the effectiveness of an adjuvanted RBD-NP vaccine in inducing robust and durable neutralizing antibody responses, providing protection against SARS-CoV-2 infection, and cross-neutralizing various variants. Adjuvants such as AS03 and AS37 significantly enhanced the immunogenicity of the vaccine and have the potential to be candidates for COVID-19 vaccines.

NATURE (2021)

Add to Collection

Article Chemistry, Physical

Polymer-templated supramolecular co-assemblies of proteins and metal oxide clusters as versatile platform for chemo-enzymatic catalysis

Xinpei Li et al.

Summary: The study demonstrates the co-assembly of proteins and metal oxide clusters on P4VP colloids via hydrogen bonding, leading to the development of efficient and selective chemo-enzymatic cascade catalysts. The synergistic effects of chemical and enzymatic catalysis in these co-assemblies result in higher oxidation activity compared to traditional bi-enzymatic systems, confirming the effectiveness of the co-assembly approach in cascade catalysis.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Key Considerations for the Development of Safe and Effective SARS-CoV-2 Subunit Vaccine: A Peptide-Based Vaccine Alternative

Ahmed O. Shalash et al.

Summary: COVID-19 has devastating effects on global health and the economy. Similarities between SARS-CoV-2 and SARS-CoV infections suggest that progress in developing SARS-CoV vaccines can be applied to SARS-CoV-2 vaccines, with a focus on careful antigen selection to avoid immune-mediated disorders.

ADVANCED SCIENCE (2021)

Add to Collection

Review Immunology

Advances in Development and Application of Influenza Vaccines

Jidang Chen et al.

Summary: Influenza A virus is a significant zoonotic pathogen that can cause severe symptoms. Vaccination remains the best option to prevent infection, although current vaccines have limitations such as high cost and production time. Recent advances and innovations may lead to the development of more effective and safe novel influenza vaccines.

FRONTIERS IN IMMUNOLOGY (2021)

Add to Collection

Letter Medicine, General & Internal

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

Danuta M. Skowronski et al.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Add to Collection

Review Immunology

A guide to vaccinology: from basic principles to new developments

Andrew J. Pollard et al.

Summary: Immunization is vital for public health policy and there are challenges ahead for immunologists in developing new vaccines. Although immunology has not contributed significantly to vaccine development so far, a better understanding of protective immunity is urgently needed to tackle difficult-to-target pathogens.

NATURE REVIEWS IMMUNOLOGY (2021)

Add to Collection

Review Nanoscience & Nanotechnology

Advancements in protein nanoparticle vaccine platforms to combat infectious disease

Nina Butkovich et al.

Summary: Protein nanoparticles are a promising vaccine platform for preventing infectious diseases, offering fewer safety concerns and strong immune responses in animal models. Continued research on these novel vaccine platforms is crucial for generating safer alternatives to current vaccines, advancing vaccines for diseases with lacking prophylactic therapies, and preparing for the rapid development of new vaccines against emerging infectious diseases.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2021)

Add to Collection

Editorial Material Biochemistry & Molecular Biology

Emergence of a novel human coronavirus threatening human health

Leo L. M. Poon et al.

NATURE MEDICINE (2020)

Add to Collection

Article Multidisciplinary Sciences

Novel technology for storage and distribution of live vaccines and other biological medicines at ambient temperature

Irnela Bajrovic et al.

SCIENCE ADVANCES (2020)

Add to Collection

News Item Multidisciplinary Sciences

THE RACE FOR CORONAVIRUS VACCINES

Ewen Callaway

NATURE (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Stiffness of HIV-1 Mimicking Polymer Nanoparticles Modulates Ganglioside-Mediated Cellular Uptake and Trafficking

Behnaz Eshaghi et al.

ADVANCED SCIENCE (2020)

Add to Collection

Review Nanoscience & Nanotechnology

A framework for designing delivery systems

Wilson Poon et al.

NATURE NANOTECHNOLOGY (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Advances in Lipid Nanoparticles for mRNA-Based Cancer Immunotherapy

Maria L. Guevara et al.

FRONTIERS IN CHEMISTRY (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Supramolecular Self-Assembled Peptide-Based Vaccines: Current State and Future Perspectives

Tuerdimaimaiti Abudula et al.

FRONTIERS IN CHEMISTRY (2020)

Add to Collection

Review Immunology

Enhancing cancer immunotherapy with nanomedicine

Darrell J. Irvine et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Add to Collection

Article Engineering, Biomedical

Nanovaccine based on a protein-delivering dendrimer for effective antigen cross-presentation and cancer immunotherapy

Jun Xu et al.

BIOMATERIALS (2019)

Add to Collection

Article Biochemistry & Molecular Biology

Innovative antigen carrier system for the development of tuberculosis vaccines

Shuxiong Chen et al.

FASEB JOURNAL (2019)

Add to Collection

Review Engineering, Chemical

A review on microfabrication of thermoplastic polymer-based microneedle arrays

Herwig Juster et al.

POLYMER ENGINEERING AND SCIENCE (2019)

Add to Collection

Review Immunology

Innovative Mucosal Vaccine Formulations Against Influenza A Virus Infections

Cynthia Calzas et al.

FRONTIERS IN IMMUNOLOGY (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Nanoparticle Size Influences Antigen Retention and Presentation in Lymph Node Follicles for Humoral Immunity

Yi-Nan Zhang et al.

NANO LETTERS (2019)

Add to Collection

Review Biotechnology & Applied Microbiology

Synthetic biology for bioengineering virus-like particle vaccines

Hayley K. Charlton Hume et al.

BIOTECHNOLOGY AND BIOENGINEERING (2019)

Add to Collection

Review Immunology

Causal relationship between immunological responses and adverse reactions following vaccination

Tetsuo Nakayama

VACCINE (2019)

Add to Collection

Review Biotechnology & Applied Microbiology

Influenza vaccines: Evaluation of the safety profile

Claudia Maria Trombetta et al.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2018)

Add to Collection

Article Engineering, Biomedical

Virus-mimetic polymer nanoparticles displaying hemagglutinin as an adjuvant-free influenza vaccine

Chaeyeon Lee et al.

BIOMATERIALS (2018)

Add to Collection

Article Nanoscience & Nanotechnology

Physical activation of innate immunity by spiky particles

Ji Wang et al.

NATURE NANOTECHNOLOGY (2018)

Add to Collection

Article Polymer Science

Polymer-Protein Core-Shell Nanoparticies for Enhanced Antigen Immunogenicity

Xiaolei Zhang et al.

ACS MACRO LETTERS (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Nanoparticulate Delivery of Cancer Cell Membrane Elicits Multiantigenic Antitumor Immunity

Ashley V. Kroll et al.

ADVANCED MATERIALS (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Virus-Mimicking Chimaeric Polymersomes Boost Targeted Cancer siRNA Therapy In Vivo

Yan Zou et al.

ADVANCED MATERIALS (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Biodegradable Viral Nanoparticle/Polymer Implants Prepared via Melt-Processing

Parker W. Lee et al.

ACS NANO (2017)

Add to Collection

Article Biochemistry & Molecular Biology

Development of Core-Shell Nanostructures by In Situ Assembly of Pyridine-Grafted Diblock Copolymer and Transferrin for Drug Delivery Applications

Lin Lu et al.

BIOMACROMOLECULES (2016)

Add to Collection

Article Multidisciplinary Sciences

Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose

Jasdave S. Chahal et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Add to Collection

Review Immunology

Recent Advances in Subunit Vaccine Carriers

Abhishek Vartak et al.

VACCINES (2016)

Add to Collection

Article Medicine, General & Internal

Efficacy of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults

Himal Lal et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Add to Collection

Review Biology

The contribution of vaccination to global health: past, present and future

Brian Greenwood

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Add to Collection

Review Chemistry, Multidisciplinary

Cancer immunotherapy: nanodelivery approaches for immune cell targeting and tracking

Joao Conniot et al.

FRONTIERS IN CHEMISTRY (2014)

Add to Collection

Article Immunology

Safety, Tolerability, and Immunogenicity of Repeated Doses of DermaVir, a Candidate Therapeutic HIV Vaccine, in HIV-Infected Patients Receiving Combination Antiretroviral Therapy

Benigno Rodriguez et al.

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2013)

Add to Collection

Article Multidisciplinary Sciences

Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies

Masaru Kanekiyo et al.

NATURE (2013)

Add to Collection

Review Engineering, Biomedical

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

Alexandre Albanese et al.

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 14 (2012)

Add to Collection

Article Chemistry, Inorganic & Nuclear

A regioselective Huisgen reaction inside a Keplerate polyoxomolybdate nanoreactor

Claire Besson et al.

DALTON TRANSACTIONS (2012)

Add to Collection

Review Multidisciplinary Sciences

Regulation of Adaptive Immunity by the Innate Immune System

Akiko Iwasaki et al.

SCIENCE (2010)

Add to Collection

Article Chemistry, Multidisciplinary

Cytosolic delivery of membrane-impermeable molecules in dendritic cells using pH-Responsive core-shell nanoparticles

Yuhua Hu et al.

NANO LETTERS (2007)

Add to Collection

© Peeref 2019-2024. All rights reserved.