4.8 Article

GPR174 mRNA Acts as a Novel Prognostic Biomarker for Patients With Sepsis via Regulating the Inflammatory Response

Related references

Note: Only part of the references are listed.
Article Biology

Complementary biosensors reveal different G-protein signaling modes triggered by GPCRs and non-receptor activators

Mikel Garcia-Marcos

Summary: Although they share similar biochemical activities in vitro, receptor and non-receptor G-protein activators promote signaling in cells in fundamentally different ways.

ELIFE (2021)

Article Immunology

Effects of Neutrophil-to-Lymphocyte Ratio Combined With Interleukin-6 in Predicting 28-Day Mortality in Patients With Sepsis

Shuangqing Liu et al.

Summary: The study found that NLR and IL-6 levels were significantly higher in deceased septic patients and could serve as independent predictors of 28-day mortality. Additionally, the combination of NLR and IL-6 significantly enhanced the predictive value of 28-day mortality.

FRONTIERS IN IMMUNOLOGY (2021)

Article Immunology

SDF4 Is a Prognostic Factor for 28-Days Mortality in Patients With Sepsis via Negatively Regulating ER Stress

Tingting Zhu et al.

Summary: This study identified the key candidate gene SDF4 through weighted gene co-expression network analysis (WGCNA) and built a prediction model for sepsis prognosis. Validation in multiple datasets showed the model's effectiveness, while also revealing the association between SDF4 and ER stress in patients with sepsis.

FRONTIERS IN IMMUNOLOGY (2021)

Article Medicine, Research & Experimental

GPR174 suppression attenuates retinopathy in angiotensin II (Ang II)-treated mice by reducing inflammation via PI3K/AKT signaling

Jianzhong Yue et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Article Multidisciplinary Sciences

A GPR174-CCL21 module imparts sexual dimorphism to humoral immunity

Ruozhu Zhao et al.

NATURE (2020)

Article Cell Biology

Gpr174-deficient regulatory T cells decrease cytokine storm in septic mice

Dongze Qiu et al.

CELL DEATH & DISEASE (2019)

Article Immunology

CAAP48, a New Sepsis Biomarker, Induces Hepatic Dysfunction in an in vitro Liver-on-Chip Model

Nancy Blaurock-Moeller et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Allergy

Mannose receptor modulates macrophage polarization and allergic inflammation through miR-511-3p

Yufeng Zhou et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)

Editorial Material Medicine, General & Internal

Recognizing Sepsis as a Global Health Priority - A WHO Resolution

Konrad Reinhart et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Immunology

The immunopathology of sepsis and potential therapeutic targets

Tom van der Poll et al.

NATURE REVIEWS IMMUNOLOGY (2017)

Article Medicine, General & Internal

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Mervyn Singer et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)

Article Critical Care Medicine

Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study

Emma E. Davenport et al.

LANCET RESPIRATORY MEDICINE (2016)

Article Endocrinology & Metabolism

Role of the X-Linked Gene GPR174 in Autoimmune Addison's Disease

C. Napier et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2015)

Article Immunology

The lysophosphatidylserine receptor GPR174 constrains regulatory T cell development and function

Michael J. Barnes et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2015)

Review Biochemistry & Molecular Biology

Novel lysophosphoplipid receptors: their structure and function

Kumiko Makide et al.

JOURNAL OF LIPID RESEARCH (2014)

Article Biochemistry & Molecular Biology

Expression of orphan G-protein coupled receptor GPR174 in CHO cells induced morphological changes and proliferation delay via increasing intracellular cAMP

Kazuya Sugita et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)

Article Biochemical Research Methods

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin et al.

BIOINFORMATICS (2013)

Article Biochemistry & Molecular Biology

Robust evidence for five new Graves disease risk loci from a staged genome-wide association analysis

Shuang-Xia Zhao et al.

HUMAN MOLECULAR GENETICS (2013)

Review Biochemistry & Molecular Biology

Action of Molecular Switches in GPCRs - Theoretical and Experimental Studies

B. Trzaskowski et al.

CURRENT MEDICINAL CHEMISTRY (2012)

Article Biochemical Research Methods

TGFα shedding assay: an accurate and versatile method for detecting GPCR activation

Asuka Inoue et al.

NATURE METHODS (2012)

Article Biochemical Research Methods

pROC: an open-source package for R and S plus to analyze and compare ROC curves

Xavier Robin et al.

BMC BIOINFORMATICS (2011)

Article Biochemical Research Methods

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet et al.

BRIEFINGS IN BIOINFORMATICS (2011)

Article Biochemical Research Methods

Immunodesign of experimental sepsis by cecal ligation and puncture

Daniel Rittirsch et al.

NATURE PROTOCOLS (2009)

Article Multidisciplinary Sciences

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor κB

Chiara Porta et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Critical Care Medicine

In-hospital cardiac arrest: incidence, prognosis and possible measures to improve survival

Claudio Sandroni et al.

INTENSIVE CARE MEDICINE (2007)

Review Physiology

Mammalian G proteins and their cell type specific functions

N Wettschureck et al.

PHYSIOLOGICAL REVIEWS (2005)