☆ 4.8 Article

Inflammatory Markers, Pulmonary Function, and Clinical Symptoms in Acute COVID-19 Among Non-Hospitalized Adolescents and Young Adults

FRONTIERS IN IMMUNOLOGY (2022)

Related references

Note: Only part of the references are listed.

Article Medicine, General & Internal

Association of Self-reported COVID-19 Infection and SARS-CoV-2 Serology Test Results With Persistent Physical Symptoms Among French Adults During the COVID-19 Pandemic

Joane Matta et al.

Summary: The study found that self-reported and laboratory-confirmed COVID-19 infections were associated with persistent physical symptoms, with the latter specifically linked to anosmia. It is suggested that persistent symptoms should not be automatically attributed to SARS-CoV-2, and a complete medical evaluation may be needed to properly identify the causes.

JAMA INTERNAL MEDICINE (2022)

Add to Collection

Article Respiratory System

Dyspnoea, lung function and CT findings 3 months after hospital admission for COVID-19

Tori Vigeland Lerum et al.

Summary: The long-term pulmonary outcomes of COVID-19 after 3 months of hospital admission include chest CT opacities and reduced diffusing capacity in one-fourth of the participants. ICU patients did not show significant differences in dyspnoea scores and lung function, but had a higher prevalence of abnormal chest CT findings.

EUROPEAN RESPIRATORY JOURNAL (2021)

Add to Collection

Review Virology

Immunity and inflammatory biomarkers in COVID-19: A systematic review

Ana Paula D. Iwamura et al.

Summary: COVID-19 is a clinical syndrome caused by SARS-CoV-2, with patients showing a range of symptoms from respiratory and gastrointestinal issues to potential multiple-organ failure. The severity of the disease is linked to the balance between antiviral and immune responses. An analysis of hospitalized patients indicated that lymphocyte counts are low in severe cases, while inflammatory markers like ESR, CRP, and IL-6 are elevated regardless of disease severity. Understanding these responses is crucial for effective treatment strategies.

REVIEWS IN MEDICAL VIROLOGY (2021)

Add to Collection

Article Respiratory System

Medium-term impact of COVID-19 on pulmonary function, functional capacity and quality of life

Fabio Anastasio et al.

Summary: This study evaluated the mid-term clinical impact of COVID-19 on respiratory function in 379 patients, finding that lung damage during acute infection correlates with the reduction in pulmonary function.

EUROPEAN RESPIRATORY JOURNAL (2021)

Add to Collection

Article Environmental Sciences

Prevalence and Determinants of Fatigue after COVID-19 in Non-Hospitalized Subjects: A Population-Based Study

Knut Stavem et al.

Summary: The study found a high prevalence of fatigue following COVID-19, which was higher than in a general norm population. Fatigue symptoms were most prevalent among women, individuals with a high symptom load, or confusion during the acute phase of COVID-19.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

Add to Collection

Article Medicine, General & Internal

Predictive symptoms for COVID-19 in the community: REACT-1 study of over 1 million people

Joshua Elliott et al.

Summary: This study identified a set of 7 symptoms that can jointly predict COVID-19, including infection with the B.1.1.7 lineage, which helps maximize the detection of potential cases in the community.

PLOS MEDICINE (2021)

Add to Collection

Article Immunology

Internalization of the Membrane Attack Complex Triggers NLRP3 Inflammasome Activation and IL-1β Secretion in Human Macrophages

Ines Diaz-del-Olmo et al.

Summary: Interleukin 1 beta (IL-1 beta) plays a crucial role in inflammation and is regulated by the inflammasome. Stimulation of LPS-primed human macrophages with sub-lytic levels of the membrane attack complex (MAC) can activate the NLRP3 inflammasome and trigger IL-1 beta release. These findings demonstrate the involvement of MAC in inflammasome activation and IL-1 beta release in human macrophages.

FRONTIERS IN IMMUNOLOGY (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Decreased quality of life and spirometric alterations even after mild-moderate COVID-19

Alberto Ordinola Navarro et al.

Summary: The study found that even mild COVID-19 patients may experience spirometric alterations during the recovery period, and there is a high rate of decline in quality of life.

RESPIRATORY MEDICINE (2021)

Add to Collection

Article Immunology

Complement Overactivation and Consumption Predicts In-Hospital Mortality in SARS-CoV-2 Infection

Gyorgy Sinkovits et al.

Summary: Uncontrolled complement activation is associated with advanced disease severity of COVID-19, with patients more likely to die when accompanied by overactivation and consumption of C3. These findings support the potential use of complement inhibitory drugs in the treatment of COVID-19.

FRONTIERS IN IMMUNOLOGY (2021)

Add to Collection

Article Pediatrics

Can Asymptomatic or Non-Severe SARS-CoV-2 Infection Cause Medium-Term Pulmonary Sequelae in Children?

Ilaria Bottino et al.

Summary: Researchers found that children who recovered from asymptomatic or mildly symptomatic SARS-CoV-2 infection showed no abnormalities in lung ultrasound, airway resistance test, forced spirometry, or diffusing capacity of the lungs for carbon monoxide. However, all subjects had IgG antibodies against SARS-CoV-2, suggesting that children may be less prone to pulmonary complications compared to adults.

FRONTIERS IN PEDIATRICS (2021)

Add to Collection

Review Infectious Diseases

Associations of immunological features with COVID-19 severity: a systematic review and meta-analysis

Zhicheng Zhang et al.

Summary: Our meta-analysis showed significantly lower levels of immune cells (CD3(+) T, CD4(+) T, CD8(+) T, B and NK cells), higher levels of cytokines (TNF-alpha, IL-5, IL-6 and IL-10) and higher levels of chemokines (MCP-1, IP-10 and eotaxin) in severe cases compared to mild cases of COVID-19. These immunological features could be useful for assessing disease severity and triaging COVID-19 patients effectively.

BMC INFECTIOUS DISEASES (2021)

Add to Collection

Article Immunology

Antibody Response to SARS-CoV-2 is Associated with Long-term Clinical Outcome in Patients with COVID-19: a Longitudinal Study

Javier Garcia-Abellan et al.

Summary: Long-COVID is associated with weak anti-SARS-CoV-2 antibody response, severity of illness, and female gender. Late clinical events and persistent symptoms in the medium and long term occur in a significant proportion of patients hospitalized for COVID-19.

JOURNAL OF CLINICAL IMMUNOLOGY (2021)

Add to Collection

Article Immunology

Distinct Cytokine and Chemokine Dysregulation in Hospitalized Children With Acute Coronavirus Disease 2019 and Multisystem Inflammatory Syndrome With Similar Levels of Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 Shedding

Nadine Peart Akindele et al.

Summary: The study revealed a distinct pattern of heightened cytokine/chemokine dysregulation in MIS-C patients compared to children with acute COVID-19, occurring across the pediatric age spectrum and with similar levels of nasopharyngeal SARS-CoV-2 RNA.

JOURNAL OF INFECTIOUS DISEASES (2021)

Add to Collection

Article Pediatrics

Cytokine profile in Egyptian children and adolescents with COVID-19 pneumonia: A multicenter study

Hala K. Shafiek et al.

Summary: This study found that children and adolescents with COVID-19 pneumonia have significantly elevated levels of many cytokines, with IL-6, IL-1β, and IP-10 being independent predictors for severe cases of COVID-19 pneumonia.

PEDIATRIC PULMONOLOGY (2021)

Add to Collection

Article Multidisciplinary Sciences

Pulmonary function and six-minute-walk test in patients after recovery from COVID-19: A prospective cohort study

Dararat Eksombatchai et al.

Summary: The study found that 17.2% of COVID-19 survivors have abnormal spirometry, including restrictive and obstructive defects. Severe COVID-19 pneumonia patients had higher prevalence rates of abnormal spirometry and residual fibrosis on chest radiographs compared to patients with mild symptoms and non-severe pneumonia.

PLOS ONE (2021)

Add to Collection

Article Physiology

Pulmonary function and functional capacity in COVID-19 survivors with persistent dyspnoea

Arturo Cortes-Telles et al.

Summary: This study aimed to explore the physiological mechanisms behind persistent dyspnoea in COVID-19 survivors. Patients with persistent dyspnoea showed lower lung function, reduced exercise capacity, increased exertional desaturation, and higher symptom ratings compared to those without persistent dyspnoea, indicating a true physiological mechanism explaining persistent dyspnoea post COVID-19.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2021)

Add to Collection

Article Cell Biology

Robust innate responses to SARS-CoV-2 in children resolve faster than in adults without compromising adaptive immunity

Maria Vono et al.

Summary: Compared to adults, children with mild SARS-CoV-2 infection display less severe symptoms despite similar initial viral load and show a faster resolution of antiviral response, with more transient activation of monocytes and dendritic cells and earlier appearance of genes associated with B cell activation.

CELL REPORTS (2021)

Add to Collection

Review Immunology

Long COVID and Post-infective Fatigue Syndrome: A Review

Carolina X. Sandler et al.

Summary: Fatigue is a prominent feature in both acute and convalescent stages of COVID-19, with lasting effects on long-term recovery. Studying post-COVID fatigue and fatigue after other infections can provide valuable insights into clinical and research approaches to assess and address this issue.

OPEN FORUM INFECTIOUS DISEASES (2021)

Add to Collection

Article Medicine, General & Internal

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

Chaolin Huang et al.

LANCET (2020)

Add to Collection

Article Multidisciplinary Sciences

A pneumonia outbreak associated with a new coronavirus of probable bat origin

Peng Zhou et al.

NATURE (2020)

Add to Collection

Editorial Material Pediatrics

Why is COVID-19 so mild in children?

Petter Brodin

ACTA PAEDIATRICA (2020)

Add to Collection

Letter Hematology

Severe COVID-19 infection and thrombotic microangiopathy: success does not come easily

Eleni Gavriilaki et al.

BRITISH JOURNAL OF HAEMATOLOGY (2020)

Add to Collection

Article Biochemistry & Molecular Biology

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

Daniel Blanco-Melo et al.

CELL (2020)

Add to Collection

Editorial Material Immunology

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

Meijuan Zheng et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2020)

Add to Collection

Article Immunology

Detectable Serum Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load (RNAemia) Is Closely Correlated With Drastically Elevated Interleukin 6 Level in Critically Ill Patients With Coronavirus Disease 2019

Xiaohua Chen et al.

CLINICAL INFECTIOUS DISEASES (2020)

Add to Collection

Article Immunology

Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China

Chuan Qin et al.

CLINICAL INFECTIOUS DISEASES (2020)

Add to Collection

Article Critical Care Medicine

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

Zhe Xu et al.

LANCET RESPIRATORY MEDICINE (2020)

Add to Collection

Article Allergy

Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19

Tobias Herold et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Add to Collection

Letter Virology

Elevated interleukin-6 and severe COVID-19: A meta-analysis

Muhammad Aziz et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

Add to Collection

Article Pediatrics

Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center's observational study

Dan Sun et al.

WORLD JOURNAL OF PEDIATRICS (2020)

Add to Collection

Article Immunology

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)

Bo Diao et al.

FRONTIERS IN IMMUNOLOGY (2020)

Add to Collection

Letter Medicine, General & Internal

Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19

Yan Zhang et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Add to Collection

Article Infectious Diseases

Estimates of the severity of coronavirus disease 2019: a model-based analysis

Robert Verity et al.

LANCET INFECTIOUS DISEASES (2020)

Add to Collection

Article Multidisciplinary Sciences

Longitudinal analyses reveal immunological misfiring in severe COVID-19

Carolina Lucas et al.

NATURE (2020)

Add to Collection

Editorial Material Pediatrics

Interleukin-6 levels in children developing SARS-CoV-2 infection

Gita Vita Soraya et al.

PEDIATRICS AND NEONATOLOGY (2020)

Add to Collection

Letter Infectious Diseases

Interleukin-6 as prognosticator in patients with COVID-19

Elisa Grifoni et al.

JOURNAL OF INFECTION (2020)

Add to Collection

Article Multidisciplinary Sciences

Sex differences in immune responses that underlie COVID-19 disease outcomes

Takehiro Takahashi et al.

NATURE (2020)

Add to Collection

Article Multidisciplinary Sciences

Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients

Jan C. Holter et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Add to Collection

Article Immunology

Predictors of chronic fatigue in adolescents six months after acute Epstein-Barr virus infection: A prospective cohort study

Maria Pedersen et al.

BRAIN BEHAVIOR AND IMMUNITY (2019)

Add to Collection

Article Critical Care Medicine

Standardization of Spirometry 2019 Update An Official American Thoracic Society and European Respiratory Society Technical Statement

Brian L. Graham et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2019)

Add to Collection

Article Immunology

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population

Mariana Gaya da Costa et al.

FRONTIERS IN IMMUNOLOGY (2018)

Add to Collection

Review Cell Biology

Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets

Andreas Barratt-Due et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2017)

Add to Collection

Article Cell Biology

Complement-mediated 'bystander' damage initiates host NLRP3 inflammasome activation

Rahul Suresh et al.

JOURNAL OF CELL SCIENCE (2016)

Add to Collection

Review Biochemistry & Molecular Biology

An international serum standard for application in assays to detect human complement activation products

Grethe Bergseth et al.

MOLECULAR IMMUNOLOGY (2013)

Add to Collection

Article Respiratory System

Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations

Philip H. Quanjer et al.

EUROPEAN RESPIRATORY JOURNAL (2012)

Add to Collection

Review Pharmacology & Pharmacy

Advances in assay of complement function and activation

Morten Harboe et al.

ADVANCED DRUG DELIVERY REVIEWS (2011)

Add to Collection

© Peeref 2019-2024. All rights reserved.