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Phase I/II study of adjuvant immunotherapy with sentinel lymph node T lymphocytes in patients with colorectal cancer
Yun-Huan Zhen et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2015)
Extended evaluation of a phase 1/2 trial on dosing, safety, immunogenicity, and overall survival after immunizations with an advanced-generation Ad5 [E1-, E2b-]-CEA(6D) vaccine in late-stage colorectal cancer
Joseph P. Balint et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2015)
Tumor-induced myeloid-derived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer
Li-Ying OuYang et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study
Chiara Cremolini et al.
LANCET ONCOLOGY (2015)
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
Jeffrey S. Weber et al.
LANCET ONCOLOGY (2015)
Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a randomised, double-blind, placebo-controlled, phase 3 trial
Jin Li et al.
LANCET ONCOLOGY (2015)
Adjuvant sorafenib for hepatocellular carcinoma after resection or ablation (STORM): a phase 3, randomised, double-blind, placebo-controlled trial
Jordi Bruix et al.
LANCET ONCOLOGY (2015)
Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study
Josep Tabernero et al.
LANCET ONCOLOGY (2015)
New developments in goblet cell mucus secretion and function
G. M. H. Birchenough et al.
MUCOSAL IMMUNOLOGY (2015)
Matrix stiffness drives epithelial mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway
Spencer C. Wei et al.
NATURE CELL BIOLOGY (2015)
Nivolumab in Previously Untreated Melanoma without BRAF Mutation
Caroline Robert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
D. T. Le et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Immune evasion in cancer: Mechanistic basis and therapeutic strategies
Dass S. Vinay et al.
SEMINARS IN CANCER BIOLOGY (2015)
Bevacizumab plus XELOX as first-line treatment of metastatic colorectal cancer: The OBELIX study
Lorenzo Antonuzzo et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2015)
Tenascin C in metastasis: A view from the invasive front
Camille M. Lowy et al.
CELL ADHESION & MIGRATION (2015)
Prognostic value of tumor-infiltrating FoxP3+ regulatory T cells in cancers: a systematic review and meta-analysis
Bin Shang et al.
SCIENTIFIC REPORTS (2015)
CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function
Eunyoung Chun et al.
CELL REPORTS (2015)
Neutrophils in Cancer: Two Sides of the Same Coin
Eileen Uribe-Querol et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2015)
Cancer Immunotherapy and Breaking Immune Tolerance: New Approaches to an Old Challenge
Amani Makkouk et al.
CANCER RESEARCH (2015)
Macrophage-secreted IL-8 induces-epithelial-mesenchymal transition in hepatocellular carcinoma cells by activating the JAK2/STAT3/Snail pathway
Xiu-Tao Fu et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2015)
Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colon
K. A. Knoop et al.
MUCOSAL IMMUNOLOGY (2015)
Effects of cytokine-induced killer cell treatment in colorectal cancer patients: A retrospective study
Jinying Zhang et al.
BIOMEDICINE & PHARMACOTHERAPY (2014)
From Truly Naive to Exhausted Senescent T Cells: When Markers Predict Functionality
Anis Larbi et al.
CYTOMETRY PART A (2014)
Aflibercept versus placebo in combination with fluorouracil, leucovorin and irinotecan in the treatment of previously treated metastatic colorectal cancer: Prespecified subgroup analyses from the VELOUR trial
Josep Tabernero et al.
EUROPEAN JOURNAL OF CANCER (2014)
Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis
Malin E. V. Johansson et al.
GUT (2014)
Different subsets of natural killer T cells may vary in their roles in health and disease
Vipin Kumar et al.
IMMUNOLOGY (2014)
Allograft inflammatory factor-1 augments macrophage phagocytotic activity and accelerates the progression of atherosclerosis in ApoE−/− mice
Tetsuya Mishima et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2014)
Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial
Edward B. Garon et al.
LANCET (2014)
Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice
Payal B. Watchmaker et al.
NATURE IMMUNOLOGY (2014)
Characterization of tumor-associated B-cell subsets in patients with colorectal cancer
Alexander Shimabukuro-Vornhagen et al.
ONCOTARGET (2014)
Desmoplasia and Chemoresistance in Pancreatic Cancer
Marvin Schober et al.
CANCERS (2014)
A Randomized Phase II Study of Immunization With Dendritic Cells Modified With Poxvectors Encoding CEA and MUC1 Compared With the Same Poxvectors Plus GM-CSF for Resected Metastatic Colorectal Cancer
Michael A. Morse et al.
ANNALS OF SURGERY (2013)
Combination of platelet count and neutrophil to lymphocyte ratio is a useful predictor of postoperative survival in patients with colorectal cancer
M. Ishizuka et al.
BRITISH JOURNAL OF CANCER (2013)
Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients
Michael A. Morse et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2013)
Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Josep Tabernero et al.
CLINICAL CANCER RESEARCH (2013)
Antiangiogehic Drugs for Colorectal Cancer: Exploring New Possibilities
Renata Ferrarotto et al.
CLINICAL COLORECTAL CANCER (2013)
Altered phenotype in peripheral blood and tumor-associated NK cells from colorectal cancer patients
Yamila S. Rocca et al.
INNATE IMMUNITY (2013)
Hepatic stellate cells in liver development, regeneration, and cancer
Chunyue Yin et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Fluorouracil, Leucovorin, and Irinotecan Plus Either Sunitinib or Placebo in Metastatic Colorectal Cancer: A Randomized, Phase III Trial
Alfredo Carrato et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
Multiplex B Cell Characterization in Blood, Lymph Nodes, and Tumors from Patients with Malignancies
A. Ali Zirakzadeh et al.
JOURNAL OF IMMUNOLOGY (2013)
Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial
Axel Grothey et al.
LANCET (2013)
Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): an open-label, randomised phase 3 trial
David Cunningham et al.
LANCET ONCOLOGY (2013)
Analysis of serum exosomal microRNAs and clinicopathologic features of patients with pancreatic adenocarcinoma
Risheng Que et al.
WORLD JOURNAL OF SURGICAL ONCOLOGY (2013)
Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions
Patrick J. Brennan et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature
Alexander Stein et al.
BMC CANCER (2012)
First-line sunitinib plus FOLFIRI in Japanese patients with unresectable/metastatic colorectal cancer: A phase II study
Yasushi Tsuji et al.
CANCER SCIENCE (2012)
Analysis of exosome release and its prognostic value in human colorectal cancer
J. Silva et al.
GENES CHROMOSOMES & CANCER (2012)
The extracellular matrix: A dynamic niche in cancer progression
Pengfei Lu et al.
JOURNAL OF CELL BIOLOGY (2012)
Addition of Aflibercept to Fluorouracil, Leucovorin, and Irinotecan Improves Survival in a Phase III Randomized Trial in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin-Based Regimen
Eric Van Cutsem et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Cutting Edge: CTLA-4 on Effector T Cells Inhibits In Trans
Emily Corse et al.
JOURNAL OF IMMUNOLOGY (2012)
Identification and proteomic profiling of exosomes in human cerebrospinal fluid
Jonathan M. Street et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2012)
Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial
Aimery de Gramont et al.
LANCET ONCOLOGY (2012)
Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine
Jeremiah R. McDole et al.
NATURE (2012)
A Randomized, Phase II Trial of Standard Triweekly Compared with Dose-Dense Biweekly Capecitabine Plus Oxaliplatin Plus Bevacizumab as First-Line Treatment for Metastatic Colorectal Cancer: XELOX-A-DVS (Dense Versus Standard)
Herbert Hurwitz et al.
ONCOLOGIST (2012)
Increased Intratumoral Neutrophil in Colorectal Carcinomas Correlates Closely with Malignant Phenotype and Predicts Patients' Adverse Prognosis
Hui-Lan Rao et al.
PLOS ONE (2012)
Origins of the Tumor Microenvironment: Quantitative Assessment of Adipose-Derived and Bone Marrow-Derived Stroma
Shannon Kidd et al.
PLOS ONE (2012)
Plasma-Derived Exosomal Survivin, a Plausible Biomarker for Early Detection of Prostate Cancer
Salma Khan et al.
PLOS ONE (2012)
B Cells Contribute to the Antitumor Activity of CpG-Oligodeoxynucleotide in a Mouse Model of Metastatic Lung Carcinoma
Rosalinda Sorrentino et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Rationale and design of decision: a double-blind, randomized, placebo-controlled phase III trial evaluating the efficacy and safety of sorafenib in patients with locally advanced or metastatic radioactive iodine (RAI)-refractory, differentiated thyroid cancer
Marcia S. Brose et al.
BMC CANCER (2011)
The absence of B lymphocytes reduces the number and function of T-regulatory cells and enhances the anti-tumor response in a murine tumor model
Tamar Tadmor et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Natural Killer Cells are Scarce in Colorectal Carcinoma Tissue Despite High Levels of Chemokines and Cytokines
Niels Halama et al.
CLINICAL CANCER RESEARCH (2011)
Functional Specializations of Intestinal Dendritic Cell and Macrophage Subsets That Control Th17 and Regulatory T Cell Responses Are Dependent on the T Cell/APC Ratio, Source of Mouse Strain, and Regional Localization
Timothy L. Denning et al.
JOURNAL OF IMMUNOLOGY (2011)
Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages
Cecilia Lasser et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
Macrophage regulation of tumor angiogenesis: Implications for cancer therapy
Mario Leonardo Squadrito et al.
MOLECULAR ASPECTS OF MEDICINE (2011)
T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis
Maria R. Parkhurst et al.
MOLECULAR THERAPY (2011)
Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria
Yuki Kinjo et al.
NATURE IMMUNOLOGY (2011)
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
Helga Ellingsgaard et al.
NATURE MEDICINE (2011)
Chimeric Antigen Receptor-Modified T Cells in Chronic Lymphoid Leukemia
David L. Porter et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Pilot Study of Sentinel-Node-Based Adoptive Immunotherapy in Advanced Colorectal Cancer
Mona Karlsson et al.
ANNALS OF SURGICAL ONCOLOGY (2010)
Putative contribution of CD56 positive cells in cetuximab treatment efficacy in first-line metastatic colorectal cancer patients
Raphael Marechal et al.
BMC CANCER (2010)
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
Kai Kessenbrock et al.
CELL (2010)
A Randomized Trial of Ex vivo CD40L Activation of a Dendritic Cell Vaccine in Colorectal Cancer Patients: Tumor-Specific Immune Responses Are Associated with Improved Survival
Richard J. Barth et al.
CLINICAL CANCER RESEARCH (2010)
Glucagon-like peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells
I. Hadjiyanni et al.
DIABETOLOGIA (2010)
High frequency of tumor-infiltrating FOXP3+ regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients
Daniel M. Frey et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Higher intratumoral infiltrated Foxp3+Treg numbers and Foxp3+/CD8+ratio are associated with adverse prognosis in resectable gastric cancer
Zhengbin Shen et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2010)
Randomized, Phase III Trial of Panitumumab With Infusional Fluorouracil, Leucovorin, and Oxaliplatin (FOLFOX4) Versus FOLFOX4 Alone As First-Line Treatment in Patients With Previously Untreated Metastatic Colorectal Cancer: The PRIME Study
Jean-Yves Douillard et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
B Cells Are Required for Optimal CD4+ and CD8+ T Cell Tumor Immunity: Therapeutic B Cell Depletion Enhances B16 Melanoma Growth in Mice
David J. DiLillo et al.
JOURNAL OF IMMUNOLOGY (2010)
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
F. Stephen Hodi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Development of Monocytes, Macrophages, and Dendritic Cells
Frederic Geissmann et al.
SCIENCE (2010)
Adaptive-Control Model for Neutrophil Orientation in the Direction of Chemical Gradients
Daniel Irimia et al.
BIOPHYSICAL JOURNAL (2009)
Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
Mojgan Ahmadzadeh et al.
BLOOD (2009)
Phase III Trial of FOLFOX plus Bevacizumab or Cediranib (AZD2171) as First-Line Treatment of Patients with Metastatic Colorectal Cancer: HORIZON III
Jane D. Robertson et al.
CLINICAL COLORECTAL CANCER (2009)
Sorafenib for Treatment of Renal Cell Carcinoma: Final Efficacy and Safety Results of the Phase III Treatment Approaches in Renal Cancer Global Evaluation Trial
Bernard Escudier et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes
Patricia A. Gonzales et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
Chemotherapy, Bevacizumab, and Cetuximab in Metastatic Colorectal Cancer
Jolien Tol et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer
Eric Van Cutsem et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Myeloid-derived suppressor cells as regulators of the immune system
Dmitry I. Gabrilovich et al.
NATURE REVIEWS IMMUNOLOGY (2009)
The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients
Takuya Osada et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2008)
The Desmoplastic Reaction Surrounding Hepatic Colorectal Adenocarcinoma Metastases Aids Tumor Growth and Survival via αv Integrin Ligation
John A. Conti et al.
CLINICAL CANCER RESEARCH (2008)
Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer
Shengming Dai et al.
MOLECULAR THERAPY (2008)
Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis
Christian Stockmann et al.
NATURE (2008)
Sorafenib in advanced hepatocellular carcinoma
Josep M. Llovet et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts
Elisabeth M. Zeisberg et al.
CANCER RESEARCH (2007)
Exosomes with immune modulatory features are present in human breast milk
Charlotte Admyre et al.
JOURNAL OF IMMUNOLOGY (2007)
Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
Eric Van Cutsem et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
The terminology issue for myeloid-derived suppressor cells
Dmitry I. Gabrilovich et al.
CANCER RESEARCH (2007)
NKT cells: T lymphocytes with innate effector functions
Luc Van Kaer
CURRENT OPINION IN IMMUNOLOGY (2007)
Tumour-associated angiogenesis in human colorectal cancer
K. A. Rmali et al.
COLORECTAL DISEASE (2007)
K-ras activation generates an inflammatory response in lung tumors
H Ji et al.
ONCOGENE (2006)
Correlation between the response to cetuximab alone or in combination with irinotecan and the activated/phosphorylated epidermal growth factor receptor in metastatic colorectal cancer
N Personeni et al.
SEMINARS IN ONCOLOGY (2005)
Increased intratumor Vα24-positive natural killer T cells:: A prognostic factor for primary colorectal carcinomas
T Tachibana et al.
CLINICAL CANCER RESEARCH (2005)
Guanylyl cyclase C: a molecular marker for staging and postoperative surveillance of patients with colorectal cancer
GS Frick et al.
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2005)
Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
LB Saltz et al.
JOURNAL OF CLINICAL ONCOLOGY (2004)
Identification and proteomic profiling of exosomes in human urine
T Pisitkun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Adjuvant, adoptive immunotherapy with tumor infiltrating lymphocytes plus interleukin-2 after radical hepatic resection for colorectal liver metastases: 5-year analysis
A Gardini et al.
JOURNAL OF SURGICAL ONCOLOGY (2004)
PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease
ER Vossenaar et al.
BIOESSAYS (2003)
IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody for treatment of head and neck cancer
RS Herbst et al.
SEMINARS IN ONCOLOGY (2002)
NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells
MC Coles et al.
JOURNAL OF IMMUNOLOGY (2000)