4.8 Article

ERAP2 Is Associated With Immune Infiltration and Predicts Favorable Prognosis in SqCLC

Related references

Note: Only part of the references are listed.
Article Oncology

Cancer Statistics, 2021

Rebecca L. Siegel et al.

Summary: Every year, the American Cancer Society projects the numbers of new cancer cases and deaths in the United States, with the latest data showing a significant decline in lung cancer mortality, while prostate cancer mortality has plateaued and breast and colorectal cancer mortality have slowed. Improvements in treatment have accelerated progress against lung cancer, leading to a record drop in overall cancer mortality.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Review Oncology

The Role of Antigen Processing and Presentation in Cancer and the Efficacy of Immune Checkpoint Inhibitor Immunotherapy

Anastasia Mpakali et al.

Summary: Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, but are only effective for a subset of patients and cancer types. Recent research emphasizes the importance of how cancer cells present molecules to the immune system in response to immunotherapy. Modulating intracellular antigen processing may enhance tumor immunogenicity and the effectiveness of ICI therapy.

CANCERS (2021)

Article Immunology

Antigen presentation in SARS-CoV-2 infection: the role of class I HLA and ERAP polymorphisms

Irma Saulle et al.

Summary: HLA molecules play a crucial role in host immune response and specific correlations have been established between certain HLA alleles and SARS-CoV-2 infection. Despite some confusion and contradictions in the data, the research aims to partially untangle this complex relationship.

HUMAN IMMUNOLOGY (2021)

Review Immunology

Immunogenetic Predictors of Severe COVID-19

Anna Malkova et al.

Summary: This study analyzed genetic factors related to the immune response to the new coronavirus infection, and identified potential gene markers associated with the development of severe COVID-19 cases. These gene markers are more common in men, suggesting population differences that need to be confirmed with additional clinical studies.

VACCINES (2021)

Article Immunology

Polymorphisms of Antigen-Presenting Machinery Genes in Non-Small Cell Lung Cancer: Different Impact on Disease Risk and Clinical Parameters in Smokers and Never-Smokers

Andrzej Wisniewski et al.

Summary: The distribution of APM polymorphic variants in NSCLC patients shows significant differences between smokers and never-smokers, indicating that ERAP1 may play a different role in anti-cancer response depending on smoking status.

FRONTIERS IN IMMUNOLOGY (2021)

Review Oncology

Antigen presentation in cancer: insights into tumour immunogenicity and immune evasion

Suchit Jhunjhunwala et al.

Summary: This review discusses the importance of antigen presentation in the success of immune checkpoint inhibition therapy and mechanisms by which tumors evade immune recognition. Tumors evade immune recognition by modulating antigen expression and altering antigen presentation.

NATURE REVIEWS CANCER (2021)

Review Medicine, Research & Experimental

Precision Management of Advanced Non-Small Cell Lung Cancer

Ching-Yao Yang et al.

ANNUAL REVIEW OF MEDICINE, VOL 71, 2020 (2020)

Review Cell Biology

The future of cancer immunotherapy: microenvironment-targeting combinations

Yonina R. Murciano-Goroff et al.

CELL RESEARCH (2020)

Article Immunology

The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia

Kimberly Seamon et al.

FRONTIERS IN IMMUNOLOGY (2020)

Review Biochemistry & Molecular Biology

The roles of ERAP1 and ERAP2 in autoimmunity and cancer immunity: New insights and perspective

Farhad Babaie et al.

MOLECULAR IMMUNOLOGY (2020)

Article Immunology

The Multifaceted Nature of Aminopeptidases ERAP1, ERAP2, and LNPEP: From Evolution to Disease

Fabiana Paladini et al.

FRONTIERS IN IMMUNOLOGY (2020)

Article Biochemical Research Methods

Generation of SARS-CoV-2 S1 Spike Glycoprotein Putative Antigenic Epitopes in Vitro by Intracellular Aminopeptidases

George Stamatakis et al.

JOURNAL OF PROTEOME RESEARCH (2020)

Review Oncology

Immunotherapy in Non-Small Cell Lung Cancer: Facts and Hopes

Deborah B. Doroshow et al.

CLINICAL CANCER RESEARCH (2019)

Article Immunology

Regulation of ERAP1 and ERAP2 genes and their disfunction in human cancer

Mirco Compagnone et al.

HUMAN IMMUNOLOGY (2019)

Article Biotechnology & Applied Microbiology

Determining cell type abundance and expression from bulk tissues with digital cytometry

Aaron M. Newman et al.

NATURE BIOTECHNOLOGY (2019)

Article Multidisciplinary Sciences

Proteogenomic landscape of squamous cell lung cancer

Paul A. Stewart et al.

NATURE COMMUNICATIONS (2019)

Review Biochemistry & Molecular Biology

The expression of FOXP3 and its role in human cancers

Hao Jia et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2019)

Review Oncology

Current and Emergent Therapy Options for Advanced Squamous Cell Lung Cancer

Mark A. Socinski et al.

JOURNAL OF THORACIC ONCOLOGY (2018)

Article Multidisciplinary Sciences

Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration

Yoong Wearn Lim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Immunology

How ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I Proteins

Jose A. Lopez de Castro

FRONTIERS IN IMMUNOLOGY (2018)

Review Multidisciplinary Sciences

The biology and management of non-small cell lung cancer

Roy S. Herbst et al.

NATURE (2018)

Review Oncology

The next generation of immunotherapy: keeping lung cancer in check

Ashwin Somasundaram et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)

Review Medicine, General & Internal

Precision Diagnosis and Treatment for Advanced Non-Small-Cell Lung Cancer

Martin Reck et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Rheumatology

Endoplasmic reticulum aminopeptidases: biology and pathogenic potential

Nigil Haroon et al.

NATURE REVIEWS RHEUMATOLOGY (2010)