4.8 Article

Exploring the Prognostic Value, Immune Implication and Biological Function of H2AFY Gene in Hepatocellular Carcinoma

Related references

Note: Only part of the references are listed.
Article Oncology

A Positive Feedback Loop of AKR1C3-Mediated Activation of NF-κB and STAT3 Facilitates Proliferation and Metastasis in Hepatocellular Carcinoma

Qingqing Zhou et al.

Summary: AKR1C3 is significantly upregulated in hepatocellular carcinoma (HCC) and associated with poor survival. Through the NF-kappa B/STAT3 signaling loop, AKR1C3 promotes cell proliferation and metastasis, suggesting it could be a promising therapeutic target in HCC.

CANCER RESEARCH (2021)

Article Oncology

The diagnostic and prognostic value of H2AFY in hepatocellular carcinoma

Xuyang Ma et al.

Summary: In this study, it was found that H2AFY is significantly overexpressed in HCC and is positively correlated with clinical characteristics of HCC patients. H2AFY may serve as a potential diagnostic and prognostic marker for HCC, as high expression predicts a poor prognosis.

BMC CANCER (2021)

Article Oncology

Prognostic and clinicopathological value of BUB1B expression in patients with lung adenocarcinoma: a meta-analysis

Jie Chen et al.

Summary: This meta-analysis identifies BUB1B as a significant biomarker for poor prognosis and clinicopathological outcomes in patients with LUAD, with high BUB1B expression associated with male sex, smoking history, and advanced TNM stage. High BUB1B expression predicts poor overall survival and progression-free survival.

EXPERT REVIEW OF ANTICANCER THERAPY (2021)

Article Multidisciplinary Sciences

Pancancer survival analysis of cancer hallmark genes

Adam Nagy et al.

Summary: This study aimed to estimate the prognostic effect of cancer hallmark genes in multiple distinct cancer types. The results showed significant heterogeneity and tissue specificity in the correlation between these genes and survival, providing valuable information for future targeted therapy development in solid tumors.

SCIENTIFIC REPORTS (2021)

Article Genetics & Heredity

Analyzing the characteristics of immune cell infiltration in lung adenocarcinoma via bioinformatics to predict the effect of immunotherapy

Yi Liao et al.

Summary: Recent studies have shown the association between tumor immune cell infiltration (ICI) with immunotherapy sensitivity and prognosis in lung adenocarcinoma (LUAD). Utilizing computational algorithms, this study identified immune cell content and ICI subtypes in LUAD patients, revealing high ICI scores were correlated with better prognosis and immunotherapeutic advantages.

IMMUNOGENETICS (2021)

Review Pharmacology & Pharmacy

Immune checkpoint inhibitors: a promising anticancer therapy

Sima Singh et al.

DRUG DISCOVERY TODAY (2020)

Review Cell Biology

The roles of histone variants in fine-tuning chromatin organization and function

Sara Martire et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)

Review Pharmacology & Pharmacy

CD38: targeted therapy in multiple myeloma and therapeutic potential for solid cancers

Ying Jiao et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2020)

Article Oncology

MacroH2A1 Immunoexpression in Breast Cancer

Giuseppe Broggi et al.

FRONTIERS IN ONCOLOGY (2020)

Article Biochemical Research Methods

TISIDB: an integrated repository portal for tumor-immune system interactions

Beibei Ru et al.

BIOINFORMATICS (2019)

Article Biochemistry & Molecular Biology

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis

Zefang Tang et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Biochemistry & Molecular Biology

Functions of N6-methyladenosine and its role in cancer

Liuer He et al.

MOLECULAR CANCER (2019)

Review Oncology

The broken cycle: E2F dysfunction in cancer

Lindsey N. Kent et al.

NATURE REVIEWS CANCER (2019)

Article Biochemistry & Molecular Biology

LinkedOmics: analyzing multi-omics data within and across 32 cancer types

Suhas V. Vasaikar et al.

NUCLEIC ACIDS RESEARCH (2018)

Review Biochemistry & Molecular Biology

STAT3 Interactors as Potential Therapeutic Targets for Cancer Treatment

Federica Laudisi et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Medicine, General & Internal

Hepatocellular carcinoma

Alejandro Forner et al.

LANCET (2018)

Article Oncology

Analysis of DNA methylation in cancer: location revisited

Alexander Koch et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2018)

Article Biochemistry & Molecular Biology

GeneMANIA update 2018

Max Franz et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Biochemistry & Molecular Biology

MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms

Marek Kozlowski et al.

EMBO REPORTS (2018)

Article Genetics & Heredity

HCCDB: A Database of Hepatocellular Carcinoma Expression Atlas

Qiuyu Lian et al.

GENOMICS PROTEOMICS & BIOINFORMATICS (2018)

Review Cell Biology

Variants of core histones and their roles in cell fate decisions, development and cancer

Marcus Buschbeck et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Review Cell Biology

Histone chaperone networks shaping chromatin function

Colin M. Hammond et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Article Oncology

Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma

Jittiporn Chaisaingmongkol et al.

CANCER CELL (2017)

Review Chemistry, Medicinal

Aurora-A Kinase: A Potent Oncogene and Target for Cancer Therapy

Min Yan et al.

MEDICINAL RESEARCH REVIEWS (2016)

Article Medicine, General & Internal

Hepatocellular carcinoma

Josep M. Llovet et al.

NATURE REVIEWS DISEASE PRIMERS (2016)

Article Biochemical Research Methods

Robust enumeration of cell subsets from tissue expression profiles

Aaron M. Newman et al.

NATURE METHODS (2015)

Article Gastroenterology & Hepatology

Current and future treatments for hepatocellular carcinoma

Alexander Schlachterman et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2015)

Article Biochemistry & Molecular Biology

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

Simon A. Forbes et al.

NUCLEIC ACIDS RESEARCH (2015)

Review Biochemistry & Molecular Biology

Histone variants: emerging players in cancer biology

Chiara Vardabasso et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2014)

Article Gastroenterology & Hepatology

Hepatocellular carcinoma: clinical frontiers and perspectives

Jordi Bruix et al.

Article Oncology

MacroH2A suppresses the proliferation of the B16 melanoma cell line

Shaorong Lei et al.

MOLECULAR MEDICINE REPORTS (2014)

Review Oncology

STAT3 Target Genes Relevant to Human Cancers

Richard L. Carpenter et al.

CANCERS (2014)

Review Oncology

MacroH2A - An epigenetic regulator of cancer

Neus Cantarino et al.

CANCER LETTERS (2013)

Article Biochemistry & Molecular Biology

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

Jianjiong Gao et al.

SCIENCE SIGNALING (2013)

Article Pathology

Differential Regulation and Predictive Potential of MacroH2A1 Isoforms in Colon Cancer

Judith C. Sporn et al.

AMERICAN JOURNAL OF PATHOLOGY (2012)

Article Biochemistry & Molecular Biology

The Atypical Histone MacroH2A1.2 Interacts with HER-2 Protein in Cancer Cells

Xiufen Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Review Biochemistry & Molecular Biology

Cyclin Dependent Kinase 1 Inhibitors: A Review of Recent Progress

Q. Wang et al.

CURRENT MEDICINAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation

Leonid Novikov et al.

MOLECULAR AND CELLULAR BIOLOGY (2011)

Article Multidisciplinary Sciences

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8

Avnish Kapoor et al.

NATURE (2010)

Review Oncology

Shared and separate functions of polo-like kinases and aurora kinases in cancer

Susanne M. A. Lens et al.

NATURE REVIEWS CANCER (2010)

Article Biochemistry & Molecular Biology

Histone macroH2A isoforms predict the risk of lung cancer recurrence

J. C. Sporn et al.

ONCOGENE (2009)

Review Cell Biology

E2F-at the crossroads of life and death

Shirley Polager et al.

TRENDS IN CELL BIOLOGY (2008)

Article Multidisciplinary Sciences

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

A Subramanian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)