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Maternal Nutrition During Late Gestation and Lactation: Association With Immunity and the Inflammatory Response in the Offspring

Journal

FRONTIERS IN IMMUNOLOGY
Volume 12, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2021.758525

Keywords

maternal nutrition; neonate; growth; disease resistance; inflammatory; immunoglobulin

Categories

Funding

  1. National Natural Science Foundation of the P.R. of China [31872364, 31802067]
  2. Guangdong Basic and Applied Basic Research Foundation [2021A1515010440]
  3. Science and Technology Program of Guangzhou [202102020056]
  4. Anhui Provincial Science and Technology Major Special Project [201903a06020002]

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Immature immune system and environmental stress increase infection risk in nursing pigs. Nutritional and physiological conditions of sows affect the growth, development, and disease resistance of the offspring. Studies have shown that providing sows with certain nutrients can regulate piglets' immunity and inflammatory response.
The immature immune system at birth and environmental stress increase the risk of infection in nursing pigs. Severe infection subsequently induces intestinal and respiratory diseases and even cause death of pigs. The nutritional and physiological conditions of sows directly affect the growth, development and disease resistance of the fetus and newborn. Many studies have shown that providing sows with nutrients such as functional oligosaccharides, oils, antioxidants, and trace elements could regulate immunity and the inflammatory response of piglets. Here, we reviewed the positive effects of certain nutrients on milk quality, immunoglobulin inflammatory response, oxidative stress, and intestinal microflora of sows, and further discuss the effects of these nutrients on immunity and the inflammatory response in the offspring.

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