4.7 Article

Effects of transforming growth factor beta-activated kinase 1 (TAK1) on apoptosis of HK-2 cells in the high glucose environment

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Long-chain non-coding RNA UCA1 inhibits renal tubular epithelial cell apoptosis by targeting microRNA-206 in diabetic nephropathy

Rucui Yu et al.

Summary: This study investigated the inhibitory effect of long-chain non-coding RNA urothelial carcinoma associated 1 (UCA1) on renal tubular epithelial cell apoptosis in diabetic nephropathy (DN) by targeting microRNA (miRNA)-206. UCA1 expression was significantly reduced in diabetic renal tubular epithelial tissues and HG-induced HK-2 cells. UCA1 inhibited HG-induced apoptosis and inflammation of renal tubular epithelial cells by inhibiting miR-206 expression. Therefore, UCA1 may serve as a potential therapeutic target for DN.

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2022)

Review Biochemistry & Molecular Biology

Cell Death in the Kidney

Giovanna Priante et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Medicine, Research & Experimental

TAK1 may promote the development of diabetic nephropathy by reducing the stability of SnoN protein

Yuanyuan Wang et al.

LIFE SCIENCES (2019)

Review Cell Biology

Cellular death, reactive oxygen species (ROS) and diabetic complications

Caroline Maria Oliveira Volpe et al.

CELL DEATH & DISEASE (2018)

Review Biochemistry & Molecular Biology

Diabetes, oxidative stress and therapeutic strategies

Luc Rochette et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)

Article Urology & Nephrology

Roles of MAPKAPK-2 and HSP27 in the reduction of renal ischemia-reperfusion injury by ischemic postconditioning in rats

Anzhou Xia et al.

INTERNATIONAL UROLOGY AND NEPHROLOGY (2014)

Article Biochemistry & Molecular Biology

Mechanism and In Vitro Pharmacology of TAK1 Inhibition by (5Z)-7-Oxozeaenol

Jiaquan Wu et al.

ACS CHEMICAL BIOLOGY (2013)

Review Immunology

Cell type-specific function of TAK1 in innate immune signaling

Adebusola A. Ajibade et al.

TRENDS IN IMMUNOLOGY (2013)

Review Pharmacology & Pharmacy

Targeting of TAK1 in inflammatory disorders and cancer

Hiroaki Sakurai

TRENDS IN PHARMACOLOGICAL SCIENCES (2012)

Article Physiology

TGF-β1-activated kinase-1 regulates inflammation and fibrosis in the obstructed kidney

Frank Y. Ma et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2011)

Article Transplantation

Delayed inhibition of p38 mitogen-activated protein kinase ameliorates renal fibrosis in obstructive nephropathy

Masashi Nishida et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2008)

Article Physiology

FR167653 inhibits fibronectin expression and apoptosis in diabetic glomeruli and in high-glucose-stimulated mesangial cells

Dong-Sub Jung et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)

Article Urology & Nephrology

TGF-β concentration specifies differential signaling profiles of growth arrest/differentiation land apoptosis in podocytes

DT Wu et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)

Article Pharmacology & Pharmacy

Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor-β type I receptor kinase in puromycin-induced nephritis

ET Grygielko et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)

Article Urology & Nephrology

p38 mitogen-activated protein kinase activation and cell localization in human glomerulonephritis: Correlation with renal injury

C Stambe et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2004)

Article Biochemistry & Molecular Biology

Transforming growth factor-β1 potentiates renal tubular epithelial cell death by a mechanism independent of smad signaling

CS Dai et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)