Journal
APPLIED SCIENCES-BASEL
Volume 12, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/app12031025
Keywords
seaweed; phlorotannin; polysaccharide; metabolic disease; cardiovascular disease
Categories
Funding
- National Research Foundation of Korea (NRF) - Korean government (Ministry of Science and ICT, MSIT) [NRF-2020R1A2C2012608]
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Cardiovascular diseases are closely linked to hypertension, type 2 diabetes mellitus, obesity, and hyperlipidemia. Bioactive compounds derived from marine seaweeds, such as polyphenols, polysaccharides, peptides, carotene, and sterol, have shown potential in improving human health and protecting against cardiovascular disorders. This review summarizes the current research on these compounds and their effects on diseases like diabetes, hypertension, hyperlipidemia, and obesity.
Cardiovascular diseases are closely related to hypertension, type 2 diabetes mellitus, obesity, and hyperlipidemia. Many studies have reported that an unhealthy diet and sedentary lifestyle are critical factors that enhance these diseases. Recently, many bioactive compounds isolated from marine seaweeds have been studied for their benefits in improving human health. In particular, several unique bioactive metabolites such as polyphenols, polysaccharides, peptides, carotene, and sterol are the most effective components responsible for these activities. This review summarizes the current in vitro, in vivo, and clinical studies related to the protective effects of bioactive compounds isolated from seaweeds against cardiovascular disorders, including anti-diabetic, anti-hypertensive, anti-hyperlipidemia, and anti-obesity effects. Therefore, this present review summarizes these concepts and provides a basis for further in-depth research.
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