4.6 Review

Molecular Profile of Skin Cancer

Journal

APPLIED SCIENCES-BASEL
Volume 11, Issue 19, Pages -

Publisher

MDPI
DOI: 10.3390/app11199142

Keywords

gene mutations; basal cell carcinoma; squamous cell carcinoma; melanoma

Funding

  1. University of Medicine and Pharmacy Grigore T Popa Iasi [6983/21.04.2020]

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Genetic mutations are linked to the occurrence of neoplasia, including skin cancer, but research on this association is limited and inconsistent. There are currently no established guidelines for molecular-level screening of skin cancer. Combinations of gene mutations may impact the biology and immune response of skin tumors, and this study focuses on the three major types of skin cancer.
Neoplasia occurs as a result of genetic mutations. Research evaluating the association between gene mutations and skin cancer is limited and has produced inconsistent results. There are no established guidelines for screening skin cancer at molecular level. It should also be noted that the combinations of some mutations may play a role in skin tumors' biology and immune response. There are three major types of skin cancer, and the originality of this study comes from its approach of each of them.

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