4.7 Review

Review on Nanoparticles and Nanostructured Materials: Bioimaging, Biosensing, Drug Delivery, Tissue Engineering, Antimicrobial, and Agro-Food Applications

Journal

NANOMATERIALS
Volume 12, Issue 3, Pages -

Publisher

MDPI
DOI: 10.3390/nano12030457

Keywords

nanostructures; nanomaterials; drug delivery systems; tissue-engineered scaffolds; wound dressings; skincare; risks and toxicities; market and regulations

Funding

  1. Ahmed Barhoum (NanoStruc Research Group, Helwan University)
  2. EgyptFrance Joint Driver (Imhotep) [43990SF]
  3. Joint Egyptian Japanese Scientific Cooperation (JEJSC) [42811]
  4. Irish Research Council [GOIPD/2020/340]
  5. Science and Engineering Research Board (SERB), Ministry of Science and Technology, India [CRG/2018/002135, SR/NM/NS-1470/2014]
  6. Nano mission, Department of Science and Technology (DST), Ministry of Science and Technology, India [CRG/2018/002135, SR/NM/NS-1470/2014]

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This review explores the potential and applications of nanomaterials in the biomedical and healthcare fields. It discusses various synthesis methods and different types of nanomaterials. Nanomaterials have promising applications in bioimaging, drug delivery, and antimicrobial fields, among others, with significant prospects for future development.
In the last few decades, the vast potential of nanomaterials for biomedical and healthcare applications has been extensively investigated. Several case studies demonstrated that nanomaterials can offer solutions to the current challenges of raw materials in the biomedical and healthcare fields. This review describes the different nanoparticles and nanostructured material synthesis approaches and presents some emerging biomedical, healthcare, and agro-food applications. This review focuses on various nanomaterial types (e.g., spherical, nanorods, nanotubes, nanosheets, nanofibers, core-shell, and mesoporous) that can be synthesized from different raw materials and their emerging applications in bioimaging, biosensing, drug delivery, tissue engineering, antimicrobial, and agro-foods. Depending on their morphology (e.g., size, aspect ratio, geometry, porosity), nanomaterials can be used as formulation modifiers, moisturizers, nanofillers, additives, membranes, and films. As toxicological assessment depends on sizes and morphologies, stringent regulation is needed from the testing of efficient nanomaterials dosages. The challenges and perspectives for an industrial breakthrough of nanomaterials are related to the optimization of production and processing conditions.

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