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Functional Validation of Osteoporosis Genetic Findings Using Small Fish Models

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Functional Characterization of a GGPPS Variant Identified in Atypical Femoral Fracture Patients and Delineation of the Role of GGPPS in Bone-Relevant Cell Types

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The mechanical impact of col11a2 loss on joints; col11a2 mutant zebrafish show changes to joint development and function, which leads to early-onset osteoarthritis

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PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2018)

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Increased mechanical loading through controlled swimming exercise induces bone formation and mineralization in adult zebrafish

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SCIENTIFIC REPORTS (2018)

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Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study

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BMJ-BRITISH MEDICAL JOURNAL (2018)

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In Toto Imaging of Dynamic Osteoblast Behaviors in Regenerating Skeletal Bone

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Skeletal malformations of Meox1-deficient zebrafish resemble human Klippel-Feil syndrome

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Phenotype loss is associated with widespread divergence of the gene regulatory landscape in evolution

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PLOS GENETICS (2018)

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Two Rare Mutations in the COL1A2 Gene Associate With Low Bone Mineral Density and Fractures in Iceland

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JOURNAL OF BONE AND MINERAL RESEARCH (2016)

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Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations

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ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease

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OSTEOPOROSIS INTERNATIONAL (2002)

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