Related references
Note: Only part of the references are listed.AG-348 (mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and adenosine triphosphate levels over a broad range of PKLR genotypes
Minke A. E. Rab et al.
HAEMATOLOGICA (2021)
Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity
Angelo D. Alessandro et al.
HAEMATOLOGICA (2021)
Testosterone replacement therapy in blood donors modulates erythrocyte metabolism and susceptibility to hemolysis in cold storage
Keisha Alexander et al.
TRANSFUSION (2021)
Acute Cycling Exercise Induces Changes in Red Blood Cell Deformability and Membrane Lipid Remodeling
Travis Nemkov et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
A Proposed Concept for Defective Mitophagy Leading to Late Stage Ineffective Erythropoiesis in Pyruvate Kinase Deficiency
Annelies Johanna van Vuren et al.
FRONTIERS IN PHYSIOLOGY (2021)
Blood donor exposome and impact of common drugs on red blood cell metabolism
Travis Nemkov et al.
JCI INSIGHT (2021)
Dried blood spot metabolomics reveals a metabolic fingerprint with diagnostic potential for Diamond Blackfan Anaemia
Birgit van Dooijeweert et al.
BRITISH JOURNAL OF HAEMATOLOGY (2021)
Author's Response: Targeting Treatments to Health Disparities
Sharon K. Hunter et al.
SCHIZOPHRENIA BULLETIN (2021)
Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality
Tiffany Thomas et al.
TRANSFUSION (2021)
Blood donor obesity is associated with changes in red blood cell metabolism and susceptibility to hemolysis in cold storage and in response to osmotic and oxidative stress
Kelsey Hazegh et al.
TRANSFUSION (2021)
Red blood cell metabolism in Rhesus macaques and humans: comparative biology of blood storage
Davide Stefanoni et al.
HAEMATOLOGICA (2020)
Hypoxic storage of red blood cells improves metabolism and post-transfusion recovery
Angelo D'Alessandro et al.
TRANSFUSION (2020)
Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies
Tingting Xie et al.
CIRCULATION RESEARCH (2020)
Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion
Richard O. Francis et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Impact of taurine on red blood cell metabolism and implications for blood storage
Lorenzo Bertolone et al.
TRANSFUSION (2020)
Metabolomics of Endurance Capacity in World Tour Professional Cyclists
Inigo San-Millan et al.
FRONTIERS IN PHYSIOLOGY (2020)
Addressing the diagnostic gaps in pyruvate kinase deficiency: Consensus recommendations on the diagnosis of pyruvate kinase deficiency
Paola Bianchi et al.
AMERICAN JOURNAL OF HEMATOLOGY (2019)
Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice
Heather L. Howie et al.
BLOOD ADVANCES (2019)
Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage
Travis Nemkov et al.
HAEMATOLOGICA (2018)
Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage
Travis Nemkov et al.
HAEMATOLOGICA (2018)
MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis
Jasmine Chong et al.
NUCLEIC ACIDS RESEARCH (2018)
Red blood cells as an organ? How deep omics characterization of the most abundant cell in the human body highlights other systemic metabolic functions beyond oxygen transport
Travis Nemkov et al.
EXPERT REVIEW OF PROTEOMICS (2018)
Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells
Julie A. Reisz et al.
TRANSFUSION (2018)
Novel mutations associated with pyruvate kinase deficiency in Brazil
Maria Carolina Costa Melo Svidnicki et al.
HEMATOLOGY TRANSFUSION AND CELL THERAPY (2018)
Plasma succinate is a predictor of mortality in critically injured patients
Angelo D'Alessandro et al.
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2017)
A three-minute method for high-throughput quantitative metabolomics and quantitative tracing experiments of central carbon and nitrogen pathways
Travis Nemkov et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2017)
Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease
Kaiqi Sun et al.
SCIENTIFIC REPORTS (2017)
Plasma succinate is a predictor of mortality in critically injured patients
Angelo D'Alessandro et al.
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2017)
On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, PIEZO1, and Gardos Channels
Virgilio L. Lew et al.
FRONTIERS IN PHYSIOLOGY (2017)
Oxidative modifications of glyceraldehyde 3-phosphate dehydrogenase regulate metabolic reprogramming of stored red blood cells
Julie A. Reisz et al.
BLOOD (2016)
Glucose 6-phosphate dehydrogenase deficient subjects may be better storers than donors of red blood cells
Vassilis L. Tzounakas et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia
Kaiqi Sun et al.
NATURE COMMUNICATIONS (2016)
Hypoxia-mediated impaired erythrocyte Lands' Cycle is pathogenic for sickle cell disease
Hongyu Wu et al.
SCIENTIFIC REPORTS (2016)
Erythrocyte pyruvate kinase deficiency: 2015 status report
Rachael F. Grace et al.
AMERICAN JOURNAL OF HEMATOLOGY (2015)
Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease
April D. Lake et al.
AMINO ACIDS (2015)
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
Edward T. Chouchani et al.
NATURE (2014)
Regulation of erythropoiesis by hypoxia-inducible factors
Volker H. Haase
BLOOD REVIEWS (2013)
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
G. M. Tannahill et al.
NATURE (2013)
Erythrocyte pyruvate kinase deficiency in an old-order Amish cohort: Longitudinal risk and disease management
Nicholas L. Rider et al.
AMERICAN JOURNAL OF HEMATOLOGY (2011)
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
Amar J. Majmundar et al.
MOLECULAR CELL (2010)
A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
Christopher B. Newgard et al.
CELL METABOLISM (2009)
Diagnostik des Pyruvatkinase-Mangels bei erhöhter Retikulozytenzahl
A. Pekrun et al.
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT (2008)
Pyruvate kinase deficiency and malaria
Kodjo Ayi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Pyruvate kinase deficiency: The genotype-phenotype association
Alberto Zanella et al.
BLOOD REVIEWS (2007)
The energy-less red blood cell is lost: erythrocyte enzyme abnormalities of glycolysis
R van Wijk et al.
BLOOD (2005)
Red cell pyruvate kinase deficiency: molecular and clinical aspects
A Zanella et al.
BRITISH JOURNAL OF HAEMATOLOGY (2005)
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
MA Selak et al.
CANCER CELL (2005)
Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deficient erythrocytes - Role of oxidative stress
D Ingrosso et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)