Related references
Note: Only part of the references are listed.Involvement of eNAMPT/TLR4 signaling in murine radiation pneumonitis: protection by eNAMPT neutralization
Alexander N. Garcia et al.
TRANSLATIONAL RESEARCH (2022)
Antitumor Activity of Asperphenin B by Induction of Apoptosis and Regulation of Glyceraldehyde-3-phosphate Dehydrogenase in Human Colorectal Cancer Cells
Woong Sub Byun et al.
JOURNAL OF NATURAL PRODUCTS (2021)
A Selective Competitive Inhibitor of Aldehyde Dehydrogenase 1A3 Hinders Cancer Cell Growth, Invasiveness and Stemness In Vitro
Edoardo L. M. Gelardi et al.
CANCERS (2021)
Molecular dynamics of targeting CD38 in multiple myeloma
Fabio Malavasi et al.
BRITISH JOURNAL OF HAEMATOLOGY (2021)
In cancer, all roads lead to NADPH
Gulam Mohmad Rather et al.
PHARMACOLOGY & THERAPEUTICS (2021)
The role of ALDH2 in tumorigenesis and tumor progression: Targeting ALDH2 as a potential cancer treatment
Hong Zhang et al.
ACTA PHARMACEUTICA SINICA B (2021)
Metabolic pathways regulating colorectal cancer initiation and progression
Sofia La Vecchia et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2020)
Vitamin C in combination with inhibition of mutant IDH1 synergistically activates TET enzymes and epigenetically modulates gene silencing in colon cancer cells
Christian Gerecke et al.
EPIGENETICS (2020)
Development of a Bioluminescent High-Throughput Screening Assay for Nicotinamide Mononucleotide Adenylyltransferase (NMNAT)
Brad A. Haubrich et al.
SLAS DISCOVERY (2020)
Targeting the NAD+ salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/β-catenin signaling via increasing Axin level
Chenyang Ye et al.
CELL COMMUNICATION AND SIGNALING (2020)
Microcystins-LR induced apoptosis via S-nitrosylation of GAPDH in colorectal cancer cells
Keyi Li et al.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2020)
SIRT2-dependent IDH1 deacetylation inhibits colorectal cancer and liver metastases
Bo Wang et al.
EMBO REPORTS (2020)
Dual disruption of aldehyde dehydrogenases 1 and 3 promotes functional changes in the glutathione redox system and enhances chemosensitivity in nonsmall cell lung cancer
Rocio Rebollido-Rios et al.
ONCOGENE (2020)
NAD- and NADPH-Contributing Enzymes as Therapeutic Targets in Cancer: An Overview
Alvinsyah Adhityo Pramono et al.
BIOMOLECULES (2020)
Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer
Davide M. Ferraris et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2020)
Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells
Luca Quattrini et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Neutralization of extracellular NAMPT (nicotinamide phosphoribosyltransferase) ameliorates experimental murine colitis
Giorgia Colombo et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2020)
Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-a]pyridines against the 1A Family
Luca Quattrini et al.
ACS MEDICINAL CHEMISTRY LETTERS (2020)
Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy
Ubaldina Galli et al.
FRONTIERS IN PHARMACOLOGY (2020)
Targeting Aldehyde Dehydrogenases to Eliminate Cancer Stem Cells in Gynecologic Malignancies
Vaishnavi Muralikrishnan et al.
CANCERS (2020)
The DNA damage response pathway as a land of therapeutic opportunities for colorectal cancer
G. Mauri et al.
ANNALS OF ONCOLOGY (2020)
First-in-human study of the PARP/tankyrase inhibitor E7449 in patients with advanced solid tumours and evaluation of a novel drug-response predictor
Ruth Plummer et al.
BRITISH JOURNAL OF CANCER (2020)
Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities
Carina Neitzel et al.
CANCERS (2020)
Crosstalk between aldehyde dehydrogenase-1 and chemoresistance in breast cancer: Insights into the role of vitamin D3
Yasmeen M. Attia et al.
LIFE SCIENCES (2020)
Location, Location, Location: Compartmentalization of NAD(+) Synthesis and Functions in Mammalian Cells
Xiaolu A. Cambronne et al.
TRENDS IN BIOCHEMICAL SCIENCES (2020)
Molecular correlates of sensitivity to PARP inhibition beyond homologous recombination deficiency in pre-clinical models of colorectal cancer point to wild-type TP53 activity
Jorgen Smeby et al.
EBIOMEDICINE (2020)
Alkannin-Induced Oxidative DNA Damage Synergizes With PARP Inhibition to Cause Cancer-Specific Cytotoxicity
Mingxin Chang et al.
FRONTIERS IN PHARMACOLOGY (2020)
Novel SIRT Inhibitor, MHY2256, Induces Cell Cycle Arrest, Apoptosis, and Autophagic Cell Death in HCT116 Human Colorectal Cancer Cells
Min Jeong Kim et al.
BIOMOLECULES & THERAPEUTICS (2020)
NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications
Huai-Qiang Ju et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
Low dose novel PARP-PI3K inhibition via nanoformulation improves colorectal cancer immunoradiotherapy
M. R. Landry et al.
MATERIALS TODAY BIO (2020)
How to conjugate the stemness marker ALDH1A1 with tumor angiogenesis, progression, and drug resistance
Valerio Ciccone et al.
CANCER DRUG RESISTANCE (2020)
NAD(+) homeostasis in health and disease
Elena Katsyuba et al.
NATURE METABOLISM (2020)
Evodiamine inhibits migration and invasion by Sirt1-mediated post-translational modulations in colorectal cancer
Peng Zhou et al.
ANTI-CANCER DRUGS (2019)
Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells
Cristina Travelli et al.
CANCER RESEARCH (2019)
Prognostic role of glycolysis for cancer outcome: evidence from 86 studies
Min Yu et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2019)
A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells
Ilana Chefetz et al.
CELL REPORTS (2019)
Glucose-6-phosphate dehydrogenase deficiency reduces susceptibility to cancer of endodermal origin
Giovanni Mario Pes et al.
ACTA ONCOLOGICA (2019)
Gluconeogenesis in cancer cells - Repurposing of a starvation-induced metabolic pathway?
Gabriele Grasmann et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2019)
Targeted mutational analysis of inflammatory bowel disease-associated colorectal cancers
Lindsay Alpert et al.
HUMAN PATHOLOGY (2019)
Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model
Ali Sohail Farooqi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling
Sudhir Chowdhry et al.
NATURE (2019)
A Novel ALDH1A1 Inhibitor Targets Cells with Stem Cell Characteristics in Ovarian Cancer
Nkechiyere G. Nwani et al.
CANCERS (2019)
A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer (vol 120, pg 183, 2019)
Vera Gorbunova et al.
BRITISH JOURNAL OF CANCER (2019)
Reactive oxygen species and cancer: A complex interaction
Sankaralingam Saikolappan et al.
CANCER LETTERS (2019)
NAD-Biosynthetic and Consuming Enzymes as Central Players of Metabolic Regulation of Innate and Adaptive Immune Responses in Cancer
Valentina Audrito et al.
FRONTIERS IN IMMUNOLOGY (2019)
Aldehyde Dehydrogenase Inhibitors for Cancer Therapeutics
Saketh S. Dinavahi et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2019)
Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group
Cristina Travelli et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation
Antonella Manago et al.
NATURE COMMUNICATIONS (2019)
Increased nicotinamide adenine dinucleotide pool promotes colon cancer progression by suppressing reactive oxygen species level
Sun M. Hong et al.
CANCER SCIENCE (2019)
Genomic and tumor biological aspects of the anticancer nicotinamide phosphoribosyltransferase inhibitor FK866 in resistant human colorectal cancer cells
Yoko Ogino et al.
GENOMICS (2019)
Sensitization of colorectal cancer to irinotecan therapy by PARP inhibitor rucaparib
Titto Augustine et al.
INVESTIGATIONAL NEW DRUGS (2019)
Poly(ADP-Ribose) Polymerase Inhibition Sensitizes Colorectal Cancer-Initiating Cells to Chemotherapy
Awad Jarrar et al.
STEM CELLS (2019)
Aldehyde Dehydrogenases: Not Just Markers, but Functional Regulators of Stem Cells
Giuseppe Vassalli
STEM CELLS INTERNATIONAL (2019)
SIRT6, a novel direct transcriptional target of FoxO3a, mediates colon cancer therapy
Yingjie Zhang et al.
THERANOSTICS (2019)
Association between alcohol consumption and colorectal cancer risk: a case-control study in the Han Chinese population
Yue Wang et al.
EUROPEAN JOURNAL OF CANCER PREVENTION (2018)
Sirt3-mediated mitochondrial fission regulates the colorectal cancer stress response by modulating the Akt/PTEN signalling pathway
Yan Wang et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Sex Differences in Cancer: Epidemiology, Genetics and Therapy
Hae-In Kim et al.
BIOMOLECULES & THERAPEUTICS (2018)
ALDH1A inhibition sensitizes colon cancer cells to chemotherapy
Z. Kozovska et al.
BMC CANCER (2018)
A Phase 2 Study of the PARP Inhibitor Celiparib Plus Temozolomide in Patients With Heavily Pretreated Metastatic Colorectal Cancer
Michael J. Pishvaian et al.
CANCER (2018)
IDH1-mutant cancer cells are sensitive to cisplatin and an IDH1-mutant inhibitor counteracts this sensitivity
Mohammed Khurshed et al.
FASEB JOURNAL (2018)
Cross resistance to diverse anticancer nicotinamide phosphoribosyltransferase inhibitors induced by FK866 treatment
Yoko Ogino et al.
Oncotarget (2018)
Expression of Aldehyde Dehydrogenase 1A1 (ALDH1A1) as a Prognostic Biomarker in Colorectal Cancer Using Immunohistochemistry
Wangshuo Yang et al.
MEDICAL SCIENCE MONITOR (2018)
Colorectal Cancer and Alcohol Consumption-Populations to Molecules
Marco Rossi et al.
CANCERS (2018)
ALDH1A1 expression is associated with poor differentiation, 'right-sidedness' and poor survival in human colorectal cancer
Lizet M. van der Waals et al.
PLOS ONE (2018)
High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling
Donghyeok Kim et al.
CELL DEATH & DISEASE (2018)
Malic Enzyme 1 (ME1) is pro-oncogenic in ApcMin/+ mice
Lorenzo M. Fernandes et al.
SCIENTIFIC REPORTS (2018)
Surveillance of Cancer Stem Cell Plasticity Using an Isoform-Selective Fluorescent Probe for Aldehyde Dehydrogenase 1A1
Chelsea Anorma et al.
ACS CENTRAL SCIENCE (2018)
Inhibition of SIRT2 limits tumour angiogenesis via inactivation of the STAT3/VEGFA signalling pathway
Fuqing Hu et al.
CELL DEATH & DISEASE (2018)
ALDH1A3 induces mesenchymal differentiation and serves as a predictor for survival in glioblastoma
Guanzhang Li et al.
CELL DEATH & DISEASE (2018)
Identification of the Nicotinamide Salvage Pathway as a New Toxification Route for Antimetabolites
Daniela Buonvicino et al.
CELL CHEMICAL BIOLOGY (2018)
CD38+ M-MDSC expansion characterizes a subset of advanced colorectal cancer patients
Tatiana A. Karakasheva et al.
JCI INSIGHT (2018)
NAMPT Is a Potent Oncogene in Colon Cancer Progression that Modulates Cancer Stem Cell Properties and Resistance to Therapy through Sirt1 and PARP
Antonio Lucena-Cacace et al.
CLINICAL CANCER RESEARCH (2018)
CD38 antibodies in multiple myeloma: back to the future
Niels W. C. J. van de Donk et al.
BLOOD (2018)
Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression
Kaiyan Liu et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
Molecular Basis of Alcohol-Related Gastric and Colon Cancer
Hye-Kyung Na et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors
Julie L. Wilsbacher et al.
MOLECULAR CANCER THERAPEUTICS (2017)
ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib
Chen Wang et al.
TRANSLATIONAL ONCOLOGY (2017)
PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth
Xiumei Zhang et al.
CELL DEATH & DISEASE (2017)
Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy
Jonathan Cole et al.
ONCOTARGET (2017)
Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor
Jeewon Kim et al.
ONCOTARGET (2017)
Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer
Ming Tang et al.
THERANOSTICS (2017)
Inhibition of malic enzyme 1 disrupts cellular metabolism and leads to vulnerability in cancer cells in glucose-restricted conditions
S. Murai et al.
ONCOGENESIS (2017)
Recent developments in the treatment of metastatic colorectal cancer
Jonathan M. Loree et al.
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2017)
Sirtuins at the crossroads of stemness, aging, and cancer
Carol O'Callaghan et al.
AGING CELL (2017)
Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers
Edwin H. Yau et al.
CANCER RESEARCH (2017)
Visfatin mediates doxorubicin resistance in human colorectal cancer cells via up regulation of multidrug resistance 1 (MDR1)
Xiaofei Yan et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2017)
A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53
Ananga Ghosh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo
Stefan Pusch et al.
ACTA NEUROPATHOLOGICA (2017)
ALDH2 polymorphism and alcohol-related cancers in Asians: a public health perspective
Jeffrey S. Chang et al.
JOURNAL OF BIOMEDICAL SCIENCE (2017)
Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors
Sara Duarte-Pereira et al.
ONCOTARGET (2016)
Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine
Ambra A. Grolla et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
SIRT1 promotes epithelial-mesenchymal transition and metastasis in colorectal cancer by regulating Fra-1 expression
Feifei Cheng et al.
CANCER LETTERS (2016)
NAD+ Kinase as a Therapeutic Target in Cancer
Philip M. Tedeschi et al.
CLINICAL CANCER RESEARCH (2016)
Absence of IDH mutation in colorectal cancers with microsatellite instability
David Tougeron et al.
DIGESTIVE AND LIVER DISEASE (2016)
A Phase I study of olaparib and irinotecan in patients with colorectal cancer: Canadian Cancer Trials Group IND 187
Eric X. Chen et al.
INVESTIGATIONAL NEW DRUGS (2016)
Association of isocitrate dehydorgenase-1 (IDH-1) mutations with elevated oncometabolite 2-hydroxyglutarate (2HG) in advanced colorectal cancer.
Nazanin Fallah-Rad et al.
JOURNAL OF CLINICAL ONCOLOGY (2016)
Dual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth
Omran Abu Aboud et al.
MOLECULAR CANCER THERAPEUTICS (2016)
Phase II Study of Olaparib (AZD-2281) After Standard Systemic Therapies for Disseminated Colorectal Cancer
Lawrence Leichman et al.
ONCOLOGIST (2016)
Clinical and therapeutic significance of sirtuin-4 expression in colorectal cancer
Guoyu Huang et al.
ONCOLOGY REPORTS (2016)
Clinicopathological significance of SIRT1 expression in colorectal cancer: A systematic review and meta analysis
Guo Zu et al.
INTERNATIONAL JOURNAL OF SURGERY (2016)
Aldehyde dehydrogenase 1A1 in stem cells and cancer
Hiroyuki Tomita et al.
ONCOTARGET (2016)
Nicotinamide Mononucleotide Adenylyl Transferase 2: A Promising Diagnostic and Therapeutic Target for Colorectal Cancer
Chunhui Cui et al.
BIOMED RESEARCH INTERNATIONAL (2016)
Efficacy and Safety of AP0866 in Patients With Refractory or Relapsed Cutaneous T-Cell Lymphoma: A Phase 2 Clinical Trial
Simone M. Goldinger et al.
JAMA DERMATOLOGY (2016)
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid
Andrea Moretti et al.
SCIENTIFIC REPORTS (2016)
Aldehyde dehydrogenases in cancer stem cells: potential as therapeutic targets
David W. Clark et al.
ANNALS OF TRANSLATIONAL MEDICINE (2016)
Tumour-suppressive function of SIRT4 in human colorectal cancer
M. Miyo et al.
BRITISH JOURNAL OF CANCER (2015)
Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status
Sybil M. Genther Williams et al.
CANCER CELL INTERNATIONAL (2015)
AK-1, a specific SIRT2 inhibitor, induces cell cycle arrest by downregulating Snail in HCT116 human colon carcinoma cells
Min Gyeong Cheon et al.
CANCER LETTERS (2015)
SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice
Myeong Jin Yoon et al.
CELL METABOLISM (2015)
Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment
Sarah Bazzocco et al.
CLINICAL CANCER RESEARCH (2015)
Characterization of Two Distinct Structural Classes of Selective Aldehyde Dehydrogenase 1A1 Inhibitors
Cynthia A. Morgan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1)
Shyh-Ming Yang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH
Jihye Yun et al.
SCIENCE (2015)
Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid
Jacqueline M. Tarrant et al.
TOXICOLOGY MECHANISMS AND METHODS (2015)
Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid
Jacqueline M. Tarrant et al.
TOXICOLOGY MECHANISMS AND METHODS (2015)
Regulative Effect of Nampt on Tumor Progression and Cell Viability in Human Colorectal Cancer
Xiaoqun Lv et al.
JOURNAL OF CANCER (2015)
Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia
Valentina Audrito et al.
BLOOD (2015)
ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways
Surendra Singh et al.
PLOS ONE (2015)
Unique Toll-Like Receptor 4 Activation by NAMPT/PBEF Induces NFκB Signaling and Inflammatory Lung Injury
Sara M. Camp et al.
SCIENTIFIC REPORTS (2015)
Suppression of Cytosolic NADPH Pool by Thionicotinamide Increases Oxidative Stress and Synergizes with Chemotherapy
Philip M. Tedeschi et al.
MOLECULAR PHARMACOLOGY (2015)
Molecular Mechanisms of Aldehyde Toxicity: A Chemical Perspective
Richard M. LoPachin et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2014)
Chemical Targeting of GAPDH Moonlighting Function in Cancer Cells Reveals Its Role in Tubulin Regulation
Da-Woon Jung et al.
CHEMISTRY & BIOLOGY (2014)
Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype
V. L. J. Whitehall et al.
EPIGENETICS (2014)
A multimarker panel for circulating tumor cells detection predicts patient outcome and therapy response in metastatic colorectal cancer
Jorge Barbazan et al.
INTERNATIONAL JOURNAL OF CANCER (2014)
Cancer-associated Isocitrate Dehydrogenase 1 (IDH1) R132H Mutation and D-2-Hydroxyglutarate Stimulate Glutamine Metabolism under Hypoxia
Zachary J. Reitman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
TARGETING ALDEHYDE DEHYDROGENASE 2: NEW THERAPEUTIC OPPORTUNITIES
Che-Hong Chen et al.
PHYSIOLOGICAL REVIEWS (2014)
Metabolomics Analysis of Metabolic Effects of Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibition on Human Cancer Cells
Vladimir Tolstikov et al.
PLOS ONE (2014)
PARP-1 Expression is Increased in Colon Adenoma and Carcinoma and Correlates with OGG1
Tomasz Dziaman et al.
PLOS ONE (2014)
Two Case Reports of Resensitization to Previous Chemotherapy with the Novel Hypoxia-Activated Hypomethylating Anticancer Agent RRx-001 in Metastatic Colorectal Cancer Patients
T. Reid et al.
CASE REPORTS IN ONCOLOGY (2014)
The role of aldehyde dehydrogenase (ALDH) in cancer drug resistance
Radoslaw Januchowski et al.
BIOMEDICINE & PHARMACOTHERAPY (2013)
Nicotinamide mononucleotide adenylyltransferase2 overexpression enhances colorectal cancer cell-kill by Tiazofurin
P. Kusumanchi et al.
CANCER GENE THERAPY (2013)
CD8-β ADP-ribosylation affects CD8+ T-cell function
Timo Lischke et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
The PARP inhibitor ABT-888 synergizes irinotecan treatment of colon cancer cell lines
David Davidson et al.
INVESTIGATIONAL NEW DRUGS (2013)
Epicatechin Gallate Impairs Colon Cancer Cell Metabolic Productivity
Susana Sanchez-Tena et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2013)
Alcohol dehydrogenase and aldehyde dehydrogenase gene polymorphisms, alcohol intake and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study
P. Ferrari et al.
EUROPEAN JOURNAL OF CLINICAL NUTRITION (2012)
Aldehyde dehydrogenase 1A1 expression in breast cancer is associated with stage, triple negativity, and outcome to neoadjuvant chemotherapy
Thaer Khoury et al.
MODERN PATHOLOGY (2012)
A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers
Russell C. Langan et al.
JOURNAL OF CANCER (2012)
The NAD metabolome - a key determinant of cancer cell biology
Alberto Chiarugi et al.
NATURE REVIEWS CANCER (2012)
Aldehyde Dehydrogenase Inhibitors: a Comprehensive Review of the Pharmacology, Mechanism of Action, Substrate Specificity, and Clinical Application
Vindhya Koppaka et al.
PHARMACOLOGICAL REVIEWS (2012)
Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer
Ying Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
NMN/NaMN Adenylyltransferase (NMNAT) and NAD Kinase (NADK) Inhibitors: Chemistry and Potential Therapeutic Applications
R. Petrelli et al.
CURRENT MEDICINAL CHEMISTRY (2011)
The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil
Maria Sanchez-Arago et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
The prognostic IDH1 R132 mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma
Fonnet E. Bleeker et al.
ACTA NEUROPATHOLOGICA (2010)
Adipocytokines as new promising markers of colorectal tumors: Adiponectin for colorectal adenoma, and resistin and visfatin for colorectal cancer
Takako Eguchi Nakajima et al.
CANCER SCIENCE (2010)
A Preclinical Study on the Rescue of Normal Tissue by Nicotinic Acid in High-Dose Treatment with APO866, a Specific Nicotinamide Phosphoribosyltransferase Inhibitor
Uffe Hogh Olesen et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant
Samantha Perez-Miller et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Omigapil Ameliorates the Pathology of Muscle Dystrophy Caused by Laminin-α2 Deficiency
Michael Erb et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors
Mark Watson et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Prognostic Relevance of Occult Nodal Micrometastases and Circulating Tumor Cells in Colorectal Cancer in a Prospective Multicenter Trial
Kazuo Koyanagi et al.
CLINICAL CANCER RESEARCH (2008)
Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily
Satori A. Marchitti et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2008)
A phase 1 trial of GMX1777: An inhibitor of nicotinamide phosphoribosyl transferase (NAMPRT)
M. J. Pishvaian et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1
Keith A. Menear et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor
Kyle Holen et al.
INVESTIGATIONAL NEW DRUGS (2008)
Nicotinamide riboside kinase structures reveal new pathways to NAD
Wolfram Tempel et al.
PLOS BIOLOGY (2007)
Elevation of cellular NAD levels by nicotinic acid and involvement of nicotinic acid phosphoribosyltransferase in human cells
Nobumasa Hara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Overexpression of poly(ADP-ribose) polymerase-1 (PARP-1) in the early stage of colorectal carcinogenesis
Katsuhiko Nosho et al.
EUROPEAN JOURNAL OF CANCER (2006)
Synthesis and antiproliferative activity of two new tiazofurin analogues with 2′-amido functionalities
M Popsavin et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
In silico design and synthesis of piperazine-1-pyrrolidine-2,5-dione scaffold-based novel malic enzyme inhibitors
YJ Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
F Berger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding
MR Hara et al.
NATURE CELL BIOLOGY (2005)
Housekeeping gene variability in normal and cancerous colorectal, pancreatic, esophageal, gastric and hepatic tissues
C Rubie et al.
MOLECULAR AND CELLULAR PROBES (2005)
Enhancement of poly-adenosine diphosphate-ribosylation in human hepatocellular carcinoma
F Nomura et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2000)
The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
A Cano et al.
NATURE CELL BIOLOGY (2000)
Share Paper
