Related references
Note: Only part of the references are listed.INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/PKA/ CREB signaling axis in a rat model of sepsis
Peng Jin et al.
EXPERIMENTAL NEUROLOGY (2021)
Dual Agonist of Farnesoid X Receptor and Takeda G Protein-Coupled Receptor 5 Inhibits Hepatitis B Virus Infection In Vitro and In Vivo
Kiyoaki Ito et al.
HEPATOLOGY (2021)
TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of caspase-8/NLRP3 after middle cerebral artery occlusion in rats
Hui Liang et al.
JOURNAL OF NEUROINFLAMMATION (2021)
TGR5 Regulates Macrophage Inflammation in Nonalcoholic Steatohepatitis by Modulating NLRP3 Inflammasome Activation
Yong Shi et al.
FRONTIERS IN IMMUNOLOGY (2021)
TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function
Gregory Merlen et al.
GUT (2020)
TGR5 promotes cholangiocarcinoma by interacting with mortalin
Ai-Di Li et al.
EXPERIMENTAL CELL RESEARCH (2020)
The Spectrum of Reactive Cholangiocytes in Primary Sclerosing Cholangitis
Maria Eugenia Guicciardi et al.
HEPATOLOGY (2020)
Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration
Giovanni Sorrentino et al.
GASTROENTEROLOGY (2020)
Intestinal Microbiome-Macrophage Crosstalk Contributes to Cholestatic Liver Disease by Promoting Intestinal Permeability in Mice
Anna Isaacs-Ten et al.
HEPATOLOGY (2020)
Hepatoprotective impact of the bile acid receptor TGR5
Gregory Merlen et al.
LIVER INTERNATIONAL (2020)
Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH)
Stefano Fiorucci et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2020)
TGR5 Signaling in Hepatic Metabolic Health
Marlena M. Holter et al.
NUTRIENTS (2020)
Bile Acids and GPBAR-1: Dynamic Interaction Involving Genes, Environment and Gut Microbiome
Piero Portincasa et al.
NUTRIENTS (2020)
Deficiency of TGR5 exacerbates immune-mediated cholestatic hepatic injury by stabilizing the β-catenin destruction complex
Jianhua Rao et al.
INTERNATIONAL IMMUNOLOGY (2020)
Molecular Pathogenesis of Cholangiocarcinoma
Peter L. Labib et al.
BMC CANCER (2019)
Cholangiocyte pathobiology
Jesus M. Banales et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)
Pruritus secondary to primary biliary cholangitis: a review of the pathophysiology and management with phototherapy
A. B. Hussain et al.
BRITISH JOURNAL OF DERMATOLOGY (2019)
Molecular Mechanisms and Signaling Pathways Involved in Sertoli Cell Proliferation
Silvina Beatriz Meroni et al.
FRONTIERS IN ENDOCRINOLOGY (2019)
Genistein protects against DSS-induced colitis by inhibiting NLRP3 inflammasome via TGR5-cAMP signaling
Yu Chen et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
Glucagon-like peptide 1 (GLP-1)
T. D. Mueller et al.
MOLECULAR METABOLISM (2019)
Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH
Adriana Carino et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2019)
TGR5 agonist ameliorates insulin resistance in skeletal muscles and improves glucose homeostasis in diabetic mice
Suling Huang et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2019)
Cholestasis induced by bile duct ligation promotes changes in the intestinal microbiome in mice
Raul Cabrera-Rubio et al.
SCIENTIFIC REPORTS (2019)
Ending Restenosis: Inhibition of Vascular Smooth Muscle Cell Proliferation by cAMP
Sarah A. Smith et al.
CELLS (2019)
Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy
Ruqi Tang et al.
GUT (2018)
FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity
Xiaoxin X. Wang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2018)
Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
Wei Jia et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)
INT-777, a bile acid receptor agonist, extenuates pancreatic acinar cells necrosis in a mouse model of acute pancreatitis
Baiqiang Li et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Mechanisms of cholangiocyte responses to injury
Keisaku Sato et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
Bile acid receptors in the biliary tree: TGR5 in physiology and disease
Kathleen Deutschmann et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression
O. Erice et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism
Preeti Pathak et al.
HEPATOLOGY (2018)
In Silico Work flow for the Discovery of Natural Products Activating the G Protein-Coupled Bile Acid Receptor
Benjamin Kirchweger et al.
FRONTIERS IN CHEMISTRY (2018)
Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2-Mediated Water Homeostasis
Suchun Li et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2018)
Role of TGR5 (GPBAR1) in Liver Disease
Verena Keitel et al.
SEMINARS IN LIVER DISEASE (2018)
Jaundice revisited: recent advances in the diagnosis and treatment of inherited cholestatic liver diseases
Huey-Ling Chen et al.
JOURNAL OF BIOMEDICAL SCIENCE (2018)
TGR5 Contributes to Hepatic Cystogenesis in Rodents With Polycystic Liver Diseases Through Cyclic Adenosine Monophosphate/Gas Signaling
Tatyana V. Masyuk et al.
HEPATOLOGY (2017)
Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism
Preeti Pathak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
TUDCA: An Agonist of the Bile Acid Receptor GPBAR1/TGR5 With Anti-Inflammatory Effects in Microglial Cells
Natalia Yanguas-Casas et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2017)
The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis
Michele Biagioli et al.
JOURNAL OF IMMUNOLOGY (2017)
Mechanisms of bile acid mediated inflammation in the liver
Man Li et al.
MOLECULAR ASPECTS OF MEDICINE (2017)
Ursolic acid activates the TGR5 receptor to enhance GLP-1 secretion in type 1-like diabetic rats
Shih-Hsiang Lo et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2017)
Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5
Angela Ladurner et al.
FRONTIERS IN PHARMACOLOGY (2017)
Clinical relevance of the bile acid receptor TGR5 in metabolism
F. Samuel van Nierop et al.
LANCET DIABETES & ENDOCRINOLOGY (2017)
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis
Adriana Carino et al.
SCIENTIFIC REPORTS (2017)
Herbal medicine Yinchenhaotang protects against α-naphthylisothiocyanate-induced cholestasis in rats
Jingyu Yan et al.
SCIENTIFIC REPORTS (2017)
Modulating bile acid pathways and TGR5 receptors for treating liver and GI diseases
Harmeet Malhi et al.
CURRENT OPINION IN PHARMACOLOGY (2017)
Glycyrrhizic acid increases glucagon like peptide-1 secretion via TGR5 activation in type 1-like diabetic rats
Lin-Yu Wang et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Bile acids and intestinal microbiota in autoimmune cholestatic liver diseases
You Li et al.
AUTOIMMUNITY REVIEWS (2017)
Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response
Shi-Ying Cai et al.
JCI INSIGHT (2017)
Tauroursodeoxycholic acid in the treatment of patients with amyotrophic lateral sclerosis
A. E. Elia et al.
EUROPEAN JOURNAL OF NEUROLOGY (2016)
TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro
Maria Reich et al.
GUT (2016)
Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis
James H. Tabibian et al.
HEPATOLOGY (2016)
Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism
Annika Wahlstrom et al.
CELL METABOLISM (2016)
Alterations and correlations of the gut microbiome, metabolism and immunity in patients with primary biliary cirrhosis
Long-Xian Lv et al.
ENVIRONMENTAL MICROBIOLOGY (2016)
Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome
Chuansheng Guo et al.
IMMUNITY (2016)
Activation of Transmembrane Bile Acid Receptor TGR5 Modulates Pancreatic Islet Cells to Promote Glucose Homeostasis
Divya P. Kumar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis
Anna Baghdasaryan et al.
JOURNAL OF HEPATOLOGY (2016)
Immunology in the liver - from homeostasis to disease
Felix Heymann et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2016)
Naturally-occurring TGR5 agonists modulating glucagon-like peptide-1 biosynthesis and secretion
Laila Jafri et al.
PEPTIDES (2016)
Development of betulinic acid as an agonist of TGR5 receptor using a new in vitro assay
Shih-Hsiang Lo et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2016)
Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis
Zizhen Gong et al.
ONCOTARGET (2016)
TGR5, Not Only a Metabolic Regulator
Cong Guo et al.
FRONTIERS IN PHYSIOLOGY (2016)
Dietary obacunone supplementation stimulates muscle hypertrophy, and suppresses hyperglycemia and obesity through the TGR5 and PPARγ pathway
Taro Horiba et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Large dose means significant effect - dose and effect relationship of Chi-Dan-Tui-Huang decoction on alpha-naphthylisothiocyanate-induced cholestatic hepatitis in rats
Yanling Zhao et al.
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2015)
Mutational mapping of the transmembrane binding site of the G-protein coupled receptor TGR5 and binding mode prediction of TGR5 agonists
Christoph G. W. Gertzen et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Fibrates and cholestasis
Nisanne S. Ghonem et al.
HEPATOLOGY (2015)
Novel Therapeutic GPCRs for Psychiatric Disorders
Hidetoshi Komatsu
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Paeoniflorin ameliorates ANIT-induced cholestasis by activating Nrf2 through an PI3K/Akt-dependent pathway in rats
Zhe Chen et al.
PHYTOTHERAPY RESEARCH (2015)
Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling
Sabrina Cipriani et al.
PLOS ONE (2015)
TGR5 and Immunometabolism: Insights from Physiology and Pharmacology
Alessia Perino et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2015)
Paeonia lactiflora Pall. protects against ANIT-induced cholestasis by activating Nrf2 via PI3K/Akt signaling pathway
Xiao Ma et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2015)
Bile acid signaling and biliary functions
Hannah Jones et al.
ACTA PHARMACEUTICA SINICA B (2015)
The Mucosa-associated Microbiota of PSC Patients is Characterized by Low Diversity and Low Abundance of Uncultured Clostridiales II
Noortje G. Rossen et al.
JOURNAL OF CROHNS & COLITIS (2015)
Novel Small Molecule Agonist of TGR5 Possesses Anti-Diabetic Effects but Causes Gallbladder Filling in Mice
Daniel A. Briere et al.
PLOS ONE (2015)
4-Benzofuranyloxynicotinamide derivatives are novel potent and orally available TGR5 agonists
Qingan Zou et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
The Bile Acid Receptor TGR5 Activates the TRPA1 Channel to Induce Itch in Mice
TinaMarie Lieu et al.
GASTROENTEROLOGY (2014)
Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades
Alan F. Hofmann et al.
JOURNAL OF LIPID RESEARCH (2014)
Discovery of Trifluoromethyl(pyrimidin-2-yl)azetidine-2-carboxamides as Potent, Orally Bioavailable TGR5 (GPBAR1) Agonists: Structure-Activity Relationships, Lead Optimization, and Chronic In Vivo Efficacy
Dean P. Phillips et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Exploitation of Cholane Scaffold for the Discovery of Potent and Selective Farnesoid X Receptor (FXR) and G-Protein Coupled Bile Acid Receptor 1 (GP-BAR1) Ligands
Carmen Festa et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Shaping macrophages function and innate immunity by bile acids: Mechanisms and implication in cholestatic liver diseases
Yvon Calmus et al.
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2014)
Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
A. David Rodrigues et al.
DRUG METABOLISM AND DISPOSITION (2014)
Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling
Anatoliy I. Masyuk et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2013)
Systemic bile acid sensing by G protein-coupled bile acid receptor 1 (GPBAR1) promotes PYY and GLP-1 release
C. Ullmer et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Pleiotropic Roles of Bile Acids in Metabolism
Thomas Q. de Aguiar Vallim et al.
CELL METABOLISM (2013)
β-catenin regulates innate and adaptive immunity in mouse liver ischemia-reperfusion injury
Bibo Ke et al.
HEPATOLOGY (2013)
The Receptor TGR5 Protects the Liver From Bile Acid Overload During Liver Regeneration in Mice
Noemie Pean et al.
HEPATOLOGY (2013)
TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease
Kazuaki Yoneno et al.
IMMUNOLOGY (2013)
Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages
Katrin Haselow et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2013)
TRC210258, a novel TGR5 agonist, reduces glycemic and dyslipidemic cardiovascular risk in animal models of diabesity
Shitalkumar Zambad et al.
Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2013)
A biliary HCO3- umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes
Simon Hohenester et al.
HEPATOLOGY (2012)
Bile acids induce monocyte differentiation toward interleukin-12 hypo-producing dendritic cells via a TGR5-dependent pathway
Riko Ichikawa et al.
IMMUNOLOGY (2012)
Design, Synthesis, and Antidiabetic Activity of 4-Phenoxynicotinamide and 4-Phenoxypyrimidine-5-carboxamide Derivatives as Potent and Orally Efficacious TGR5 Agonists
Hongliang Duan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Perspective: TGR5 (Gpbar-1) in liver physiology and disease
Verena Keitel et al.
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2012)
Bile Acids Induce Inflammatory Genes in Hepatocytes A Novel Mechanism of Inflammation during Obstructive Cholestasis
Katryn Allen et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
Beckley K. Davis et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 29 (2011)
Anti-obesity and anti-hyperglycemic effects of the dietary citrus limonoid nomilin in mice fed a high-fat diet
Eri Ono et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading
Thijs W. H. Pols et al.
CELL METABOLISM (2011)
TGR5 in the Biliary Tree
Verena Keitel et al.
DIGESTIVE DISEASES (2011)
The G-Protein-Coupled Bile Acid Receptor, Gpbar1 (TGR5), Negatively Regulates Hepatic Inflammatory Response Through Antagonizing Nuclear Factor Kappa Light-Chain Enhancer of Activated B Cells (NF-κB) in Mice
Yan-Dong Wang et al.
HEPATOLOGY (2011)
Dual Farnesoid X Receptor/TGR5 Agonist INT-767 Reduces Liver Injury in the Mdr2-/- (Abcb4-/-) Mouse Cholangiopathy Model by Promoting Biliary HCO3- Output
Anna Baghdasaryan et al.
HEPATOLOGY (2011)
TGR5 as a Therapeutic Target for Treating Obesity
Min Zhong
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2010)
Genome-Wide Association Analysis in Primary Sclerosing Cholangitis
Tom H. Karlsen et al.
GASTROENTEROLOGY (2010)
The Binary HCO3- Umbrella: A Unifying Hypothesis on Pathogenetic and Therapeutic Aspects of Fibrosing Cholangiopathies
Ulrich Beuers et al.
HEPATOLOGY (2010)
Structure-Activity Relationship Study of Betulinic Acid, A Novel and Selective TGR5 Agonist, and Its Synthetic Derivatives: Potential Impact in Diabetes
Cedric Genet et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Functional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 Agonist
Giovanni Rizzo et al.
MOLECULAR PHARMACOLOGY (2010)
TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis
Charles Thomas et al.
CELL METABOLISM (2009)
The cAMP Effectors Epac and Protein Kinase A (PKA) Are Involved in the Hepatic Cystogenesis of an Animal Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Jesus M. Banales et al.
HEPATOLOGY (2009)
The Membrane-Bound Bile Acid Receptor TGR5 Is Localized in the Epithelium of Human Gallbladders
Verena Keitel et al.
HEPATOLOGY (2009)
Cyclic Adenosine Monophosphate Suppresses the Transcription of Proinflammatory Cytokines via the Phosphorylated c-Fos Protein
Keiko Koga et al.
IMMUNITY (2009)
Discovery of 6α-Ethyl-23(S)-methylcholic Acid (S-EMCA, INT-777) as a Potent and Selective Agonist for the TGR5 Receptor, a Novel Target for Diabesity
Roberto Pellicciari et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Suppression of LPS-Induced TNF-α Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105
Estelle A. Wall et al.
SCIENCE SIGNALING (2009)
The Nuclear Factor NF-κB Pathway in Inflammation
Toby Lawrence
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)
Expression and function of the bile acid receptor TGR5 in Kupffer cells
Verena Keitel et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Novel potent and selective bile acid derivatives as TGR5 agonists: Biological screening, structure-activity relationships, and molecular modeling studies
Hiroyuki Sato et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Targeting bile-acid signalling for metabolic diseases
Charles Thomas et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea
Hiroyuki Sato et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile
Noritaka Minagawa et al.
GASTROENTEROLOGY (2007)
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice
Takaharu Maruyama et al.
JOURNAL OF ENDOCRINOLOGY (2006)
Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1
S Katsuma et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
cAMP stimulates the secretory and proliferative capacity of the rat intrahepatic biliary epithelium through changes in the PKA/Src/MEK/ERK1/2 pathway
H Francis et al.
JOURNAL OF HEPATOLOGY (2004)
Dual role of PKA in phenotypic modulation of vascular smooth muscle cells by extracellular ATP
DK Hogarth et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
The cholangiopathies: Disorders of biliary epithelia
KN Lazaridis et al.
GASTROENTEROLOGY (2004)
A G protein-coupled receptor responsive to bile acids
Y Kawamata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
6α-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity
R Pellicciari et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
The pathobiology of biliary epithelia
G Alpini et al.
HEPATOLOGY (2002)