Journal
CATALYSTS
Volume 11, Issue 12, Pages -Publisher
MDPI
DOI: 10.3390/catal11121436
Keywords
gold; silver; dihydroquinazolinone; tandem reaction; cascade reaction
Categories
Ask authors/readers for more resources
The gold-catalyzed cascade process for the synthesis of dihydroquinazolinone scaffolds exhibits good yields, high regioselectivity, and broad substrate scope. It can also be applied to the synthesis of tetracyclic dihydroquinazolinones and seven-membered ring-fused dihydroquinazolinones.
A gold-catalyzed cascade process for the synthesis of dihydroquinazolinone scaffolds was developed. A series of gold catalysts were screened for this tandem transformation, and the (PPh3)AuCl/AgOTf catalyst combination was found to be the best catalyst system. This method is characterized by good yields, high regioselectivity, and broad substrate scope. This method is also applicable to the synthesis of tetracyclic dihydroquinazolinones and seven-membered ring-fused dihydroquinazolinones.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available