Journal
CATALYSTS
Volume 11, Issue 10, Pages -Publisher
MDPI
DOI: 10.3390/catal11101222
Keywords
lipase; immobilization; support; protocol; biocatalysis; co-immobilization; biocatalyst; enzyme; novel techniques
Categories
Funding
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) [311062/2019-9]
- [001]
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The market for industrial enzymes is growing rapidly, with lipases being the most widely used industrial biocatalysts. However, challenges such as low stability and complex solutions require new materials and technologies to improve their performance.
The market for industrial enzymes has witnessed constant growth, which is currently around 7% a year, projected to reach $10.5 billion in 2024. Lipases are hydrolase enzymes naturally responsible for triglyceride hydrolysis. They are the most expansively used industrial biocatalysts, with wide application in a broad range of industries. However, these biocatalytic processes are usually limited by the low stability of the enzyme, the half-life time, and the processes required to solve these problems are complex and lack application feasibility at the industrial scale. Emerging technologies create new materials for enzyme carriers and sophisticate the well-known immobilization principles to produce more robust, eco-friendlier, and cheaper biocatalysts. Therefore, this review discusses the trending studies and industrial applications of the materials and protocols for lipase immobilization, analyzing their advantages and disadvantages. Finally, it summarizes the current challenges and potential alternatives for lipases at the industrial level.
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