Journal
ADVANCED MATERIALS INTERFACES
Volume 9, Issue 9, Pages -Publisher
WILEY
DOI: 10.1002/admi.202101872
Keywords
antimicrobial; array; layered double hydroxide; surface disinfection
Funding
- Institute of Bioengineering and Bioimaging
- Institute of Materials Research and Engineering, Science and Engineering Research Council
- Agency for Science, Technology and Research
- National Research Foundation
- Prime Minister's Office, Singapore under its NRF Competitive Research Program [NRF-CRP19-2017-02]
- Biomedical Research Council
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Vertically aligned layered double hydroxide (V-LDH) arrays with good topology have been grown on various substrates using a hydrolysis method. The V-LDH surface has enhanced antibacterial properties and biocompatibility, making it potentially useful in a wide range of applications.
Vertically aligned layered double hydroxide (V-LDH) array has been growing on various substrates by a simple solution hydrolysis method. The surface shows good topology with LDH edges extending upward, which can potentially rupture the attached bacteria cells and kill them. V-LDH after calcination shows remarkable enhanced antibacterial properties. Not only do the edges become thinner and sharper, the surface also becomes highly hydrophilic. It is found that surface potential of V-LDH does not change its antibacterial property. However, the hydrophilicity significantly enhances antibacterial properties. In vitro and in vivo studies demonstrate that the V-LDH surface has good biocompatibility. The V-LDH antibacterial coating has potentially broad applications due to its good antibacterial properties and biocompatibility.
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