4.5 Article

Advances in the Development of Trifluoromethoxylation Reagents

Journal

SYMMETRY-BASEL
Volume 13, Issue 12, Pages -

Publisher

MDPI
DOI: 10.3390/sym13122380

Keywords

pharmaceutical drugs; agrochemicals; trifluoromethoxylation; trifluoromethylation; fluorination; reagents

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This review briefly discusses traditional methods for synthesizing CF3-O-containing compounds, as well as critically evaluates known trifluoromethoxylating reagents, focusing on their preparation, synthetic generality, and limitations.
This review provides a short summary of the traditional methods for synthesis of CF3-O-containing compounds, followed by a critical overview of known trifluoromethoxylating reagents, focusing on their preparation, synthetic generality and limitations.

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